ACACB ELISA Kit for Human(Homo sapiens) | EIAab.comACACB ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > ACACB(Gene name) > Human

ACACB (Gene name),

Acetyl-CoA carboxylase 2 (Protein name ), ACACB_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

ACACB(ACC2;ACCB);

Protein name:

Acetyl-CoA carboxylase 2;

Alternative:

ACC-beta;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.

Function:

ACC-beta may be involved in the provision of malonyl-CoA or in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Subcellular Location:

Endomembrane system May associate with membranes.

Protein Attributes:

Sequence length:

2458

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

750:

800:

850:

900:

950:

1000:

1050:

1100:

1150:

1200:

1250:

1300:

1350:

1400:

1450:

1500:

1550:

1600:

1650:

1700:

1750:

1800:

1850:

1900:

1950:

2000:

2050:

2100:

2150:

2200:

2250:

2300:

2350:

2400:

2450:

2458:

TMDSPAST

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

Pfam:

PF08326

SMR:

O00763

MIM:

601557

KEGG:

hsa:32

STRING:

9606.ENSP00000367079

UniGene:

Hs.234898

String:

O00763

Uniprot:

O00763

FOR

ELISA Kit for Human Acetyl-CoA carboxylase 2

CLIA Kit for Human Acetyl-CoA carboxylase 2

Polyclonal Antibody for Human Acetyl-CoA carboxylase 2

Monoclonal Antibody for Human Acetyl-CoA carboxylase 2

Protein for Human Acetyl-CoA carboxylase 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms."
Abu-Elheiga L. , Almarza-Ortega D.B. , Baldini A. , Wakil S.J.
J. Biol. Chem.272:10669-10677(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
tissue: Liver.
2.

"Expression, purification, and characterization of human and rat acetyl coenzyme A carboxylase (ACC) isozymes."
Cheng D. , Chu C.-H. , Chen L. , Feder J.N. , Mintier G.A. , Wu Y. , Cook J.W. , Harpel M.R. , Locke G.A. , An Y. , Tamura J.K.
Protein Expr. Purif.51:11-21(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);COFACTOR;BIOPHYSICOCHEMICAL PROPERTIES;CATALYTIC ACTIVITY;ENZYME REGULATION;VARIANT ILE-2141
3.

"Corrected sequence for human acetyl-CoA carboxylase 2 obtained by alignment to human genomic DNA and PCR cloning from human skeletal muscle and heart cDNA."
Peng X.R. , Lindgren K. , Corneliussen B.
Submitted (2003-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT ILE-2141
tissue: Heart.
4.

"Alternative splicing in the human acetyl-CoA carboxylase 2 (ACC2) gene."
Mao J. , Wakil S.J.
Submitted (2003-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Heart.
5.

"The finished DNA sequence of human chromosome 12."
Scherer S.E. , Muzny D.M. , Buhay C.J. , Chen R. , Cree A. , Ding Y. , Dugan-Rocha S. , Gill R. , Gunaratne P. , Harris R.A. , Hawes A.C. , Hernandez J. , Hodgson A.V. , Hume J. , Jackson A. , Khan Z.M. , Kovar-Smith C. , Lewis L.R. , more...
Nature440:346-351(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.

"Identification of a second human acetyl-CoA carboxylase gene."
Widmer J. , Fassihi K.S. , Schlichter S.C. , Wheeler K.S. , Crute B.E. , King N. , Nutile-Mcmenemy N. , Noll W.W. , Daniel S. , Ha J. , Kim K.-H. , Witters L.A.
Biochem. J.316:915-922(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1324-2109
tissue: Adipose tissue.
7.

"The subcellular localization of acetyl-CoA carboxylase 2."
Abu-Elheiga L. , Brinkley W.R. , Zhong L. , Chirala S.S. , Woldegiorgis G. , Wakil S.J.
Proc. Natl. Acad. Sci. U.S.A.97:1444-1449(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
8.

"Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle."
Wojtaszewski J.F. , MacDonald C. , Nielsen J.N. , Hellsten Y. , Hardie D.G. , Kemp B.E. , Kiens B. , Richter E.A.
Am. J. Physiol.284:E813-E822(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-222 BY AMPK
9.

"A quantitative atlas of mitotic phosphorylation."
Dephoure N. , Zhou C. , Villen J. , Beausoleil S.A. , Bakalarski C.E. , Elledge S.J. , Gygi S.P.
Proc. Natl. Acad. Sci. U.S.A.105:10762-10767(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Cervix carcinoma.
10.

"ACC2 is expressed at high levels in human white adipose and has an isoform with a novel N-terminus."
Castle J.C. , Hara Y. , Raymond C.K. , Garrett-Engele P. , Ohwaki K. , Kan Z. , Kusunoki J. , Johnson J.M.
PLoS ONE4:E4369-E4369(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: BIOPHYSICOCHEMICAL PROPERTIES;ALTERNATIVE SPLICING (ISOFORM 3);TISSUE SPECIFICITY
11.

"Crystal structure of Spot 14, a modulator of fatty acid synthesis."
Colbert C.L. , Kim C.W. , Moon Y.A. , Henry L. , Palnitkar M. , McKean W.B. , Fitzgerald K. , Deisenhofer J. , Horton J.D. , Kwon H.J.
Proc. Natl. Acad. Sci. U.S.A.107:18820-18825(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CATALYTIC ACTIVITY;SUBUNIT;ENZYME REGULATION;INTERACTION WITH MID1IP1
12.

"Crystal structure of the biotin carboxylase domain of human acetyl-CoA carboxylase 2."
Cho Y.S. , Lee J.I. , Shin D. , Kim H.T. , Cheon Y.H. , Seo C.I. , Kim Y.E. , Hyun Y.L. , Lee Y.S. , Sugiyama K. , Park S.Y. , Ro S. , Cho J.M. , Lee T.G. , Heo Y.S.
Proteins70:268-272(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS) OF 217-775
13.

"Solution structure of RSGI RUH-053, an apo-biotin carboxy carrier protein from human transcarboxylase."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-10) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 885-971
14.

"Core signaling pathways in human pancreatic cancers revealed by global genomic analyses."
Jones S. , Zhang X. , Parsons D.W. , Lin J.C. , Leary R.J. , Angenendt P. , Mankoo P. , Carter H. , Kamiyama H. , Jimeno A. , Hong S.M. , Fu B. , Lin M.T. , Calhoun E.S. , Kamiyama M. , Walter K. , Nikolskaya T. , Nikolsky Y. , more...
Science321:1801-1806(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] LEU-193

Product Feedback Wall

* Email:
*Comments: