ACAP1 ELISA Kit for Human(Homo sapiens) | EIAab.comACAP1 ELISA Kit for Human(Homo sapiens)

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ACAP1 (Gene name),

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1 (Protein name ), ACAP1_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

ACAP1(CENTB1;KIAA0050);

Protein name:

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1;

Alternative:

Centaurin-beta-1(Cnt-b1);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with GTP-bound ARF6. Interacts with third cytoplasmic loop of SLC2A4/GLUT4. Interacts with CLTC. Interacts with GULP1. Forms a complex with GDP-bound ARF6 and GULP1.

Function:

GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface.

Subcellular Location:

N/A

Protein Attributes:

Sequence length:

740

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

740:

EAAQGQAGDE | TYLDIFRDFS | LMASDDPEKL | SRRSHDLHTL |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

Q15027

MIM:

607763

STRING:

9606.ENSP00000158762

UniGene:

Hs.337242

Pfam:

PF00023

Pfam:

PF12796

String:

Q15027

KEGG:

hsa:9744

Uniprot:

Q15027

FOR

ELISA Kit for Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

CLIA Kit for Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

Polyclonal Antibody for Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

Monoclonal Antibody for Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

Protein for Human Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1."
Nomura N. , Nagase T. , Miyajima N. , Sazuka T. , Tanaka A. , Sato S. , Seki N. , Kawarabayasi Y. , Ishikawa K. , Tabata S.
DNA Res.1:223-229(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Bone marrow.
2.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-08) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Lymph.
4.

"ACAPs are arf6 GTPase-activating proteins that function in the cell periphery."
Jackson T.R. , Brown F.D. , Nie Z. , Miura K. , Foroni L. , Sun J. , Hsu V.W. , Donaldson J.G. , Randazzo P.A.
J. Cell Biol.151:627-638(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;ENZYME REGULATION;TISSUE SPECIFICITY;MUTAGENESIS OF ARG-448
5.

"Phosphorylation of ACAP1 by Akt regulates the stimulation-dependent recycling of integrin beta1 to control cell migration."
Li J. , Ballif B.A. , Powelka A.M. , Dai J. , Gygi S.P. , Hsu V.W.
Dev. Cell9:663-673(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;PHOSPHORYLATION AT SER-554;IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH ITGB1;SUBCELLULAR LOCATION;MUTAGENESIS OF SER-14; SER-29; SER-277; THR-289; SER-358; THR-389; THR-461; SER-554; SER-568; THR-711; TYR-712 AND SER-724
6.

"Nitroproteins from a human pituitary adenoma tissue discovered with a nitrotyrosine affinity column and tandem mass spectrometry."
Zhan X. , Desiderio D.M.
Anal. Biochem.354:279-289(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NITRATION [LARGE SCALE ANALYSIS] AT TYR-485;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Pituitary adenoma.
7.

"Cooperation of phosphoinositides and BAR domain proteins in endosomal tubulation."
Shinozaki-Narikawa N. , Kodama T. , Shibasaki Y.
Traffic7:1539-1550(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PHOSPHOLIPIDS;MUTAGENESIS OF LYS-274
8.

"Regulation of Arf6 and ACAP1 signaling by the PTB-domain-containing adaptor protein GULP."
Ma Z. , Nie Z. , Luo R. , Casanova J.E. , Ravichandran K.S.
Curr. Biol.17:722-727(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH GULP AND ARF6;MUTAGENESIS OF ARG-448
9.

"An ACAP1-containing clathrin coat complex for endocytic recycling."
Li J. , Peters P.J. , Bai M. , Dai J. , Bos E. , Kirchhausen T. , Kandror K.V. , Hsu V.W.
J. Cell Biol.178:453-464(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CLTC
10.

"Mechanistic insights into regulated cargo binding by ACAP1 protein."
Bai M. , Pang X. , Lou J. , Zhou Q. , Zhang K. , Ma J. , Li J. , Sun F. , Hsu V.W.
J. Biol. Chem.287:28675-28685(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.30 ANGSTROMS) OF 378-740 WILD TYPE AND MUTANT ASP-554 IN COMPLEX WITH ITGB1 PEPTIDE AND ZINC IONS;FUNCTION;INTERACTION WITH ITGB1;MUTAGENESIS OF SER-554
11.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ARG-114 AND GLN-129

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