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Index > Protein center > ACCN1(Gene name) > Human
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  • ACCN1 (Gene name),
  • Amiloride-sensitive cation channel 1, neuronal (Protein name ),  ACCN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ACCN1(ACCN;BNAC1;MDEG);
    Protein name:
    Amiloride-sensitive cation channel 1, neuronal;
    Alternative:
    Amiloride-sensitive brain sodium channel;Acid-sensing ion channel 2(ASIC2);Brain sodium channel 1(BNC1;BNaC1);Amiloride-sensitive cation channel neuronal 1;Mammalian degenerin homolog;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with STOM (By similarity). Interacts with PRKCABP and ACCN3.
    Function:
    Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.
    Protein Attributes:
    Sequence length:
    512
    Sequence:
    50:
    MDLKESPSEG | SLQPSSIQIF | ANTSTLHGIR | HIFVYGPLTI | RRVLWAVAFV | 
    100:
    GSLGLLLVES | SERVSYYFSY | QHVTKVDEVV | AQSLVFPAVT | LCNLNGFRFS | 
    150:
    RLTTNDLYHA | GELLALLDVN | LQIPDPHLAD | PSVLEALRQK | ANFKHYKPKQ | 
    200:
    FSMLEFLHRV | GHDLKDMMLY | CKFKGQECGH | QDFTTVFTKY | GKCYMFNSGE | 
    250:
    DGKPLLTTVK | GGTGNGLEIM | LDIQQDEYLP | IWGETEETTF | EAGVKVQIHS | 
    300:
    QSEPPFIQEL | GFGVAPGFQT | FVATQEQRLT | YLPPPWGECR | SSEMGLDFFP | 
    350:
    VYSITACRID | CETRYIVENC | NCRMVHMPGD | APFCTPEQHK | ECAEPALGLL | 
    400:
    AEKDSNYCLC | RTPCNLTRYN | KELSMVKIPS | KTSAKYLEKK | FNKSEKYISE | 
    450:
    NILVLDIFFE | ALNYETIEQK | KAYEVAALLG | DIGGQMGLFI | GASILTILEL | 
    500:
    FDYIYELIKE | KLLDLLGKEE | DEGSHDENVS | TCDTMPNHSE | TISHTVNVPL | 
    512:
    QTTLGTLEEI | AC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    KEGG:
    String:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    ELISA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    ELISA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    CLIA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    CLIA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    CLIA Kit for Human Amiloride-sensitive cation channel 1, neuronal
    Polyclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Polyclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Polyclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Monoclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Monoclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Monoclonal Antibody for Human Amiloride-sensitive cation channel 1, neuronal
    Protein for Human Amiloride-sensitive cation channel 1, neuronal
    Protein for Human Amiloride-sensitive cation channel 1, neuronal
    Protein for Human Amiloride-sensitive cation channel 1, neuronal

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