Accn1 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAccn1 ELISA Kit for Rat(Rattus norvegicus)

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Accn1 (Gene name),

Amiloride-sensitive cation channel 1, neuronal (Protein name ), ACCN1_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Accn1(Asic2;Bnac1;Mdeg);

Protein name:

Amiloride-sensitive cation channel 1, neuronal;

Alternative:

Amiloride-sensitive brain sodium channel;Acid-sensing ion channel 2;Amiloride-sensitive cation channel neuronal 1;Amiloride-sensitive brain sodium channel 2;Mammalian degenerin homolog(MDEG);Brain sodium channel 1(BNC1;BNaC1);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Homotrimer or heterotrimer with other ASIC proteins (By similarity). Interacts with PRKCABP and STOM (By similarity). Interacts with ACCN2. Isoform 2 interacts with ACCN3.

Function:

Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Activation by an extracellular pH drop is followed by a rapid pH-independent inactivation. Heteromeric channel assembly seems to modulate channel properties.

Subcellular Location:

Cell membrane Multi-pass membrane protein Localized at the plasma membrane of neurons, in the soma and punctated peripheral processes.

Protein Attributes:

Sequence length:

512

Sequence:

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