Acd ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAcd ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Acd(Gene name) > Rat

Acd (Gene name),

Adrenocortical dysplasia protein homolog (Protein name ), ACD_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Acd;

Protein name:

Adrenocortical dysplasia protein homolog;

Alternative:

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Component of the shelterin complex (telosome) composed of TERF1, TERF2, TINF2, TERF2IP ACD and POT1. Forms heterodimers with POT1. Identified in a complex with POT1 and single-stranded telomeric DNA. Interacts with STN1/OBFC1 and TINF2.

Function:

Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomer elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis.

Subcellular Location:

Nucleus Chromosome telomere

Protein Attributes:

Sequence length:

417

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

417:

LVAWALNIVM | ESELPQV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

10116.ENSRNOP00000056334

UniGene:

Rn.8611

SMR:

Q4FZR5

KEGG:

rno:307798

String:

Q4FZR5

Pfam:

PF11509

Uniprot:

Q4FZR5

FOR

ELISA Kit for Rat Adrenocortical dysplasia protein homolog

CLIA Kit for Rat Adrenocortical dysplasia protein homolog

Polyclonal Antibody for Rat Adrenocortical dysplasia protein homolog

Monoclonal Antibody for Rat Adrenocortical dysplasia protein homolog

Protein for Rat Adrenocortical dysplasia protein homolog

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Thymus.

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