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Index > Protein center > Chrna3(Gene name) > Rat
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  • Chrna3 (Gene name),
  • Neuronal acetylcholine receptor subunit alpha-3 (Protein name ),  ACHA3_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Chrna3(Acra3);
    Protein name:
    Neuronal acetylcholine receptor subunit alpha-3;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Neuronal AChR is composed of two different types of subunits: alpha and beta. Alpha-3 subunit can be combined to beta-2 or beta-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly.
    Function:
    After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
    Subcellular Location:
    Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    499
    Sequence:
    50:
    MGVVLLPPPL | SMLMLVLMLL | PAASASEAEH | RLFQYLFEDY | NEIIRPVANV | 
    100:
    SHPVIIQFEV | SMSQLVKVDE | VNQIMETNLW | LKQIWNDYKL | KWKPSDYQGV | 
    150:
    EFMRVPAEKI | WKPDIVLYNN | ADGDFQVDDK | TKALLKYTGE | VTWIPPAIFK | 
    200:
    SSCKIDVTYF | PFDYQNCTMK | FGSWSYDKAK | IDLVLIGSSM | NLKDYWESGE | 
    250:
    WAIIKAPGYK | HEIKYNCCEE | IYQDITYSLY | IRRLPLFYTI | NLIIPCLLIS | 
    300:
    FLTVLVFYLP | SDCGEKVTLC | ISVLLSLTVF | LLVITETIPS | TSLVIPLIGE | 
    350:
    YLLFTMIFVT | LSIVITVFVL | NVHYRTPTTH | TMPTWVKAVF | LNLLPRVMFM | 
    400:
    TRPTSGEGDT | PKTRTFYGAE | LSNLNCFSRA | DSKSCKEGYP | CQDGTCGYCH | 
    450:
    HRRVKISNFS | ANLTRSSSSE | SVNAVLSLSA | LSPEIKEAIQ | SVKYIAENMK | 
    499:
    AQNVAKEIQD | DWKYVAMVID | RIFLWVFILV | CILGTAGLFL | QPLMARDDT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    ELISA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    CLIA Kit for Rat Neuronal acetylcholine receptor subunit alpha-3
    Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Polyclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Monoclonal Antibody for Rat Neuronal acetylcholine receptor subunit alpha-3
    Protein for Rat Neuronal acetylcholine receptor subunit alpha-3
    Protein for Rat Neuronal acetylcholine receptor subunit alpha-3
    Protein for Rat Neuronal acetylcholine receptor subunit alpha-3
    Protein for Rat Neuronal acetylcholine receptor subunit alpha-3
    Protein for Rat Neuronal acetylcholine receptor subunit alpha-3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation of a cDNA clone coding for a possible neural nicotinic acetylcholine receptor alpha-subunit."
      Boulter J. , Evans K. , Goldman D.J. , Martin G. , Treco D. , Heinemann S.F. , Patrick J.
      Nature319:368-374(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Functional expression of two neuronal nicotinic acetylcholine receptors from cDNA clones identifies a gene family."
      Boulter J. , Connolly J.G. , Deneris E.S. , Goldman D.J. , Heinemann S.F. , Patrick J.
      Proc. Natl. Acad. Sci. U.S.A.84:7763-7767(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Characterization of an acetylcholine receptor alpha 3 gene promoter and its activation by the POU domain factor SCIP/Tst-1."
      Yang X. , McDonough J. , Fyodorov D. , Morris M. , Wang F. , Deneris E.S.
      J. Biol. Chem.269:10252-10264(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-21
      tissue: Liver.
    4. 4.
      "Quantitative phosphoproteomics of vasopressin-sensitive renal cells: regulation of aquaporin-2 phosphorylation at two sites."
      Hoffert J.D. , Pisitkun T. , Wang G. , Shen R.-F. , Knepper M.A.
      Proc. Natl. Acad. Sci. U.S.A.103:7159-7164(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-407 AND SER-410;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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