Gene name:
CHRNB4 (ACRB4) ;
Protein name:
Neuronal acetylcholine receptor subunit beta-4 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
Neuronal AChR is composed of two different types of subunits: alpha and beta. Beta-4 subunit can be combined to alpha-2, alpha-3 or alpha-4 to give rise to functional receptors. Interacts with RIC3; which is required for proper folding and assembly.
Function:
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
Subcellular Location:
Cell junction
synapse
postsynaptic cell membrane
Multi-pass membrane protein
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MRSALPLVLF | SLVALCGRGD | CRVANAEEKL | MDDLLNKTRY | NNLIRPATSS |
100:
SQLISIQLQL | SLAQLISVNE | REQIMTTNIW | LKQEWTDYRL | AWNSSRYEGV |
150:
NILRIPANRV | WLPDIVLYNN | ADGSYEVSLY | TNVVVRSNGS | VMWLPPAICK |
200:
SACKIEVKHF | PFDQQNCTLK | FRSWTYDHTE | IDMVLKMPTA | SMDDFTPSGE |
250:
WDIVALPGRR | TVNPQDPSYV | DVTYDFIIKR | KPLFYTINLI | IPCVLITSLA |
300:
ILVFYLPSDC | GEKMTLCISV | LLALTVFLLL | ISKIVPPTSL | NVPLIGKYLM |
350:
FTMVLVTFSI | VTSVCVLNVH | HRSPSTHTMA | PWVKRCFLHK | LPTFLFIKRP |
400:
RQQPSRAPQS | SLARLTKSEA | TTTTTLAMGP | TSSSNLYGNS | MYFVNPGLAA |
450:
PKSPVASDSA | GIPRDFRLRS | SGRFRQDVQE | ALEGVSFIAQ | HMKSDDLDQS |
496:
VIEDWKYVAM | VVDRLFLWVF | VVVCVLGTVG | LFLPPLFQTH | TPSEEP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Mouse
Chicken
Bovine
ELISA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
ELISA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
ELISA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
ELISA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
ELISA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
CLIA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
CLIA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
CLIA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
CLIA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
CLIA Kit for Bovine Neuronal acetylcholine receptor subunit beta-4
Polyclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Polyclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Polyclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Polyclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Polyclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Monoclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Monoclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Monoclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Monoclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Monoclonal Antibody for Bovine Neuronal acetylcholine receptor subunit beta-4
Protein for Bovine Neuronal acetylcholine receptor subunit beta-4
Protein for Bovine Neuronal acetylcholine receptor subunit beta-4
Protein for Bovine Neuronal acetylcholine receptor subunit beta-4
Protein for Bovine Neuronal acetylcholine receptor subunit beta-4
Protein for Bovine Neuronal acetylcholine receptor subunit beta-4
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Neuronal nicotinic acetylcholine receptors on bovine chromaffin cells: cloning, expression, and genomic organization of receptor subunits."
Campos-Caro A.
,
Smillie F.I.
,
Dominguez del Toro E.
,
Rovira J.C.
,
Vicente-Agullo F.
,
Chapuli J.
,
Juiz J.M.
,
Sala S.
,
Sala F.
,
Ballesta J.J.
,
Criado M.
J. Neurochem.68:488-497(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Adrenal medulla .