CHRM2 ELISA Kit for Pig(Sus scrofa) | EIAab.comCHRM2 ELISA Kit for Pig(Sus scrofa)

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Index > Protein center > CHRM2(Gene name) > Pig

CHRM2 (Gene name),

Muscarinic acetylcholine receptor M2 (Protein name ), ACM2_PIG from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

CHRM2;

Protein name:

Muscarinic acetylcholine receptor M2;

Alternative:

Organism:

Pig (Sus scrofa).

General Annotation

Sub Unit:

Interacts with ARRB1 and ARRB2. Interacts with GNB2L1/RACK1; the interaction regulates CHRM2 internalization.

Function:

The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.

Subcellular Location:

Cell membrane Multi-pass membrane protein Cell junction synapse postsynaptic cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

466

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

466:

FKHLLMCHYK | NIGATR

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Ssc.16247

Pfam:

PF00001

KEGG:

ssc:397498

Uniprot:

P06199

FOR

ELISA Kit for Pig Muscarinic acetylcholine receptor M2

CLIA Kit for Pig Muscarinic acetylcholine receptor M2

Polyclonal Antibody for Pig Muscarinic acetylcholine receptor M2

Monoclonal Antibody for Pig Muscarinic acetylcholine receptor M2

Protein for Pig Muscarinic acetylcholine receptor M2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Primary structure of porcine cardiac muscarinic acetylcholine receptor deduced from the cDNA sequence."
Kubo T. , Maeda A. , Sugimoto K. , Akiba I. , Mikami A. , Takahashi H. , Haga T. , Haga K. , Ichiyama A. , Kangawa K. , Matsuo H. , Hirose T. , Numa S.
FEBS Lett.209:367-372(1986) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
2.

"Primary structure and biochemical properties of an M2 muscarinic receptor."
Peralta E.G. , Winslow J.W. , Peterson G.L. , Smith D.H. , Ashkenazi A. , Ramachandran J. , Schimerlik M.I. , Capon D.J.
Science236:600-606(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];PARTIAL PROTEIN SEQUENCE;SUBCELLULAR LOCATION
3.

"Synergistic regulation of m2 muscarinic acetylcholine receptor desensitization and sequestration by G protein-coupled receptor kinase-2 and beta-arrestin-1."
Schlador M.L. , Nathanson N.M.
J. Biol. Chem.272:18882-18890(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION;FUNCTION;SUBCELLULAR LOCATION
4.

"RACK1 associates with muscarinic receptors and regulates M(2) receptor trafficking."
Reiner C.L. , McCullar J.S. , Kow R.L. , Le J.H. , Goodlett D.R. , Nathanson N.M.
PLoS ONE5:E13517-E13517(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GNB2L1;SUBCELLULAR LOCATION

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