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Index > Protein center > Acot13(Gene name) > Mouse
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  • Acot13 (Gene name),
  • Acyl-coenzyme A thioesterase 13 (Protein name ),  ACO13_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Acot13(Them2);
    Protein name:
    Acyl-coenzyme A thioesterase 13(Acyl-CoA thioesterase 13);
    Alternative:
    Thioesterase superfamily member 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotetramer. Interacts with PCTP.
    Function:
    Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates. Can also hydrolyze 3-hydroxyphenylacetyl-CoA (in vitro).
    Subcellular Location:
    Cytoplasm Mitochondrion
    Protein Attributes:
    Sequence length:
    140
    Sequence:
    50:
    MSSMTQNLRE | VMKVMFKVPG | FDRVLEKVTL | VSAAPEKLIC | EMKVEEQHTN | 
    100:
    KLGTLHGGLT | ATLVDSISTM | ALMCTERGAP | GVSVDMNITY | MSPAKIGEEI | 
    140:
    VITAHILKQG | KTLAFASVDL | TNKTTGKLIA | QGRHTKHLGN | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Acyl-CoA thioesterase 13
    ELISA Kit for Mouse Acyl-CoA thioesterase 13
    CLIA Kit for Mouse Acyl-CoA thioesterase 13
    CLIA Kit for Mouse Acyl-CoA thioesterase 13
    Polyclonal Antibody for Mouse Acyl-CoA thioesterase 13
    Polyclonal Antibody for Mouse Acyl-CoA thioesterase 13
    Monoclonal Antibody for Mouse Acyl-CoA thioesterase 13
    Monoclonal Antibody for Mouse Acyl-CoA thioesterase 13
    Protein for Mouse Acyl-CoA thioesterase 13
    Protein for Mouse Acyl-CoA thioesterase 13

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
      tissue: Stomach.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      "Human thioesterase superfamily member 2 (hTHEM2) is co-localized with beta-tubulin onto the microtubule."
      Cheng Z. , Bao S. , Shan X. , Xu H. , Gong W.
      Biochem. Biophys. Res. Commun.350:850-853(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    4. 4.
      "Interacting proteins dictate function of the minimal START domain phosphatidylcholine transfer protein/StarD2."
      Kanno K. , Wu M.K. , Agate D.S. , Fanelli B.J. , Wagle N. , Scapa E.F. , Ukomadu C. , Cohen D.E.
      J. Biol. Chem.282:30728-30736(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PCTP;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    5. 5.
      "Thioesterase superfamily member 2 (Them2)/acyl-CoA thioesterase 13 (Acot13): A homotetrameric hotdog fold thioesterase with selectivity for long chain fatty acyl-CoAs."
      Wei J. , Kang H.W. , Cohen D.E.
      Biochem. J.421:311-322(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES;ENZYME REGULATION;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    6. 6.
      "Thioesterase superfamily member 2/acyl-CoA thioesterase 13 (Them2/Acot13) regulates hepatic lipid and glucose metabolism."
      Kang H.W. , Niepel M.W. , Han S. , Kawano Y. , Cohen D.E.
      FASEB J.26:2209-2221(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE;TISSUE SPECIFICITY
    7. 7.
      "Thioesterase superfamily member 2/Acyl-CoA thioesterase 13 (Them2/Acot13) regulates adaptive thermogenesis in mice."
      Kang H.W. , Ozdemir C. , Kawano Y. , LeClair K.B. , Vernochet C. , Kahn C.R. , Hagen S.J. , Cohen D.E.
      J. Biol. Chem.288:33376-33386(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;DISRUPTION PHENOTYPE
    8. 8.
      "Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways."
      Rardin M.J. , Newman J.C. , Held J.M. , Cusack M.P. , Sorensen D.J. , Li B. , Schilling B. , Mooney S.D. , Kahn C.R. , Verdin E. , Gibson B.W.
      Proc. Natl. Acad. Sci. U.S.A.110:6601-6606(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-27; LYS-37; LYS-43; LYS-108 AND LYS-127;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    9. 9.
      "Crystal structure of thioesterase superfamily member 2 from Mus musculus."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2009-02) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.72 ANGSTROMS)
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