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Index > Protein center > ACSL1(Gene name) > Human
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  • ACSL1 (Gene name),
  • Long-chain-fatty-acid--CoA ligase 1 (Protein name ),  ACSL1_HUMAN from NCBI database.
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  • General Annotation
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  • Gene name:
    ACSL1(FACL1;FACL2;LACS;LACS1;LACS2);
    Protein name:
    Long-chain-fatty-acid--CoA ligase 1;
    Alternative:
    Long-chain acyl-CoA synthetase 1(LACS 1);Acyl-CoA synthetase 1(ACS1);Long-chain fatty acid-CoA ligase 2;Long-chain acyl-CoA synthetase 2(LACS 2);Palmitoyl-CoA ligase 2;Palmitoyl-CoA ligase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially uses palmitoleate, oleate and linoleate.
    Subcellular Location:
    Mitochondrion outer membrane Single-pass type III membrane protein Peroxisome membrane Single-pass type III membrane protein Microsome membrane Single-pass type III membrane protein Endoplasmic reticulum membrane Single-pass type III membrane protein
    Protein Attributes:
    Sequence length:
    698
    Sequence:
    50:
    MQAHELFRYF | RMPELVDFRQ | YVRTLPTNTL | MGFGAFAALT | TFWYATRPKP | 
    100:
    LKPPCDLSMQ | SVEVAGSGGA | RRSALLDSDE | PLVYFYDDVT | TLYEGFQRGI | 
    150:
    QVSNNGPCLG | SRKPDQPYEW | LSYKQVAELS | ECIGSALIQK | GFKTAPDQFI | 
    200:
    GIFAQNRPEW | VIIEQGCFAY | SMVIVPLYDT | LGNEAITYIV | NKAELSLVFV | 
    250:
    DKPEKAKLLL | EGVENKLIPG | LKIIVVMDAY | GSELVERGQR | CGVEVTSMKA | 
    300:
    MEDLGRANRR | KPKPPAPEDL | AVICFTSGTT | GNPKGAMVTH | RNIVSDCSAF | 
    350:
    VKATENTVNP | CPDDTLISFL | PLAHMFERVV | ECVMLCHGAK | IGFFQGDIRL | 
    400:
    LMDDLKVLQP | TVFPVVPRLL | NRMFDRIFGQ | ANTTLKRWLL | DFASKRKEAE | 
    450:
    LRSGIIRNNS | LWDRLIFHKV | QSSLGGRVRL | MVTGAAPVSA | TVLTFLRAAL | 
    500:
    GCQFYEGYGQ | TECTAGCCLT | MPGDWTAGHV | GAPMPCNLIK | LVDVEEMNYM | 
    550:
    AAEGEGEVCV | KGPNVFQGYL | KDPAKTAEAL | DKDGWLHTGD | IGKWLPNGTL | 
    600:
    KIIDRKKHIF | KLAQGEYIAP | EKIENIYMRS | EPVAQVFVHG | ESLQAFLIAI | 
    650:
    VVPDVETLCS | WAQKRGFEGS | FEELCRNKDV | KKAILEDMVR | LGKDSGLKPF | 
    698:
    EQVKGITLHP | ELFSIDNGLL | TPTMKAKRPE | LRNYFRSQID | DLYSTIKV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    String:
    SMR:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    E15275h
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    E15275r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    E15275m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    U15275h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    U15275r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    U15275m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    P15275Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    P15275Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Cat.:
    P15275Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Monoclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Monoclonal Antibody for Human Long-chain-fatty-acid--CoA ligase 1
    Protein for Human Long-chain-fatty-acid--CoA ligase 1
    Protein for Human Long-chain-fatty-acid--CoA ligase 1
    Protein for Human Long-chain-fatty-acid--CoA ligase 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Human long-chain acyl-CoA synthetase: structure and chromosomal location."
      Abe T. , Fujino T. , Fukuyama R. , Minoshima S. , Shimizu N. , Toh H. , Suzuki H. , Yamamoto T.
      J. Biochem.111:123-128(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Liver.
    2. 2.
      "Molecular cloning and sequencing of human palmitoyl-CoA ligase and its tissue specific expression."
      Ghosh B. , Barbosa E. , Singh I.
      Mol. Cell. Biochem.151:77-81(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 395-698 (ISOFORM 2)
    4. 4.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    7. 7.
      Bienvenut W.V.
      Submitted (2005-06) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-8; 12-19; 341-349; 377-386; 562-572; 633-640 AND 655-675;ACETYLATION AT MET-1;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: B-cell lymphoma.
    8. 8.
      "Identification and molecular characterization of acyl-CoA synthetase in human red cells and erythroid precursor."
      Malhotra K.T. , Malhotra K. , Lubin B.H. , Kuypers F.A.
      Biochem. J.344:135-143(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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