Actn2 ELISA Kit for Mouse(Mus musculus) | EIAab.comActn2 ELISA Kit for Mouse(Mus musculus)

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Actn2 (Gene name),

Alpha-actinin-2 (Protein name ), ACTN2_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Actn2;

Protein name:

Alpha-actinin-2;

Alternative:

F-actin cross-linking protein;Alpha-actinin skeletal muscle isoform 2;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer; antiparallel. Also forms heterodimers with ACTN3. Interacts with ADAM12, MYOZ1, MYOZ2 and MYOZ3. Interacts via its C-terminal region with the LDB3 PDZ domain. Interacts with XIRP2. Interacts with DST (via N-terminus).

Function:

F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein.

Subcellular Location:

Cytoplasm myofibril sarcomere Z line Colocalizes with MYOZ1 and FLNC at the Z-lines of skeletal muscle.

Protein Attributes:

Sequence length:

894

Sequence:

50:

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650:

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894:

RRELPPDQAQ | YCIKRMPPYS | GPGSVPGALD | YTAFSSALYG | ESDL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9JI91

Pfam:

PF00307

SMR:

Q9JI91

UniGene:

Mm.37638

KEGG:

mmu:11472

Uniprot:

Q9JI91

FOR

ELISA Kit for Mouse Alpha-actinin-2

CLIA Kit for Mouse Alpha-actinin-2

Polyclonal Antibody for Mouse Alpha-actinin-2

Monoclonal Antibody for Mouse Alpha-actinin-2

Protein for Mouse Alpha-actinin-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy."
Mills M. , Yang N. , Weinberger R. , Vander Woude D.L. , Beggs A.H. , Easteal S. , North K.N.
Hum. Mol. Genet.10:1335-1346(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Skeletal muscle.
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
4.

"Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha-actinin-2, is required for myoblast fusion."
Galliano M.-F. , Huet C. , Frygelius J. , Polgren A. , Wewer U.M. , Engvall E.
J. Biol. Chem.275:13933-13939(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ADAM12
5.

"BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin."
Steiner-Champliaud M.F. , Schneider Y. , Favre B. , Paulhe F. , Praetzel-Wunder S. , Faulkner G. , Konieczny P. , Raith M. , Wiche G. , Adebola A. , Liem R.K. , Langbein L. , Sonnenberg A. , Fontao L. , Borradori L.
Exp. Cell Res.316:297-313(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION

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