Acvr1c ELISA Kit for Rat(Rattus norvegicus) | EIAab.comAcvr1c ELISA Kit for Rat(Rattus norvegicus)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > Acvr1c(Gene name) > Rat

Acvr1c (Gene name),

Activin receptor type-1C (Protein name ), ACV1C_RAT from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

Acvr1c(Alk7);

Protein name:

Activin receptor type-1C;

Alternative:

Activin receptor-like kinase 7(ALK-7);Activin receptor type IC(ACTR-IC);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds the type 2 receptor protein ACVR2A.

Function:

Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.

Subcellular Location:

Membrane Single-pass type I membrane protein

Protein Attributes:

Sequence length:

493

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

493:

CEALRVMGRI | MRECWYANGA | ARLTALRVKK | TISQLCVKED | CKA

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

String:

P70539

KEGG:

rno:245921

UniGene:

Rn.10580

SMR:

P70539

Pfam:

PF01064

Uniprot:

P70539

FOR

ELISA Kit for Rat Activin receptor type-1C

CLIA Kit for Rat Activin receptor type-1C

Polyclonal Antibody for Rat Activin receptor type-1C

Monoclonal Antibody for Rat Activin receptor type-1C

Protein for Rat Activin receptor type-1C

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of a novel type I receptor serine/threonine kinase for the TGF beta superfamily from rat brain."
Tsuchida K. , Sawchenko P.E. , Nishikawa S. , Vale W.W.
Mol. Cell. Neurosci.7:467-478(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;MUTAGENESIS OF THR-194 AND LYS-222
strain: Sprague-Dawley.
tissue: Brain.
2.

"A novel type I receptor serine-threonine kinase predominantly expressed in the adult central nervous system."
Ryden M. , Imamura T. , Joernvall H. , Belluardo N. , Neveu I. , Trupp M. , Okadome T. , ten Dijke P. , Ibanez C.F.
J. Biol. Chem.271:30603-30609(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue: Brain.
3.

"Activin isoforms signal through type I receptor serine/threonine kinase ALK7."
Tsuchida K. , Nakatani M. , Yamakawa N. , Hashimoto O. , Hasegawa Y. , Sugino H.
Mol. Cell. Endocrinol.220:59-65(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 139-159;FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;INTERACTION WITH ACVR2A; ACTIVIN AB AND B
4.

"The MH1 domains of smad2 and smad3 are involved in the regulation of the ALK7 signals."
Watanabe R. , Yamada Y. , Ihara Y. , Someya Y. , Kubota A. , Kagimoto S. , Kuroe A. , Iwakura T. , Shen Z.-P. , Inada A. , Adachi T. , Ban N. , Miyawaki K. , Sunaga Y. , Tsuda K. , Seino Y.
Biochem. Biophys. Res. Commun.254:707-712(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY;MUTAGENESIS OF THR-194
5.

"The orphan receptor serine/threonine kinase ALK7 signals arrest of proliferation and morphological differentiation in a neuronal cell line."
Joernvall H. , Blokzijl A. , ten Dijke P. , Ibanez C.F.
J. Biol. Chem.276:5140-5146(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;TISSUE SPECIFICITY

Product Feedback Wall

* Email:
*Comments: