Aspartoacylase-2 (Protein name
), ACY3_MOUSE from NCBI database.
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General Annotation
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Antigen Annotation
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3D
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Predicted Eptitope
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Vaild Sequence
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Gene name:
Acy3(Aspa2);
Protein name:
Aspartoacylase-2;
Alternative:
Aminoacylase III(AAIII);Acylase III;Hepatitis C virus core-binding protein 1(HCBP1);Aminoacylase-3(ACY-3);Hepatitis C virus core-binding protein 1(HCBP1);
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homotetramer.
Function:
Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
Subcellular Location:
Apical cell membrane
Peripheral membrane protein
Cytoplasm
Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm.
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Precision
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Recovery
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Linearity
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References
1.
"The mouse aspartoacylase-3 gene (ACY-3) generates two mRNA isoforms by alternative splicing of 5' untranslated region." Chen H.
,
Peng J.
,
Huang C.-H.
Submitted (2001-03) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
"Identification of a novel aspartoacylase homolog (ACY-3) in human and mouse kidneys." Huang C.-H.
,
Chen H.
,
Peng J.
,
Chen Y.
Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
"Cloning and sequence analysis of cDNA encoding hepatitis C virus core-binding protein 1 (HCBP1) from mouse." Li K.
,
Cheng J.
,
Zhang L.
,
Wang L.
,
Lu Y.
,
Wang G.
,
Liu Y.
Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBSTRATE SPECIFICITY
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: STRUCTURE BY ELECTRON MICROSCOPY (16 ANGSTROMS);SUBUNIT
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH SUBSTRATES;ZINC-BINDING SITES;SUBUNIT;COFACTOR;MUTAGENESIS OF ARG-63 AND TYR-287