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Index > Protein center > Acy3(Gene name) > Mouse
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  • Acy3 (Gene name),
  • Aspartoacylase-2 (Protein name ),  ACY3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Acy3(Aspa2);
    Protein name:
    Aspartoacylase-2;
    Alternative:
    Aminoacylase III(AAIII);Acylase III;Hepatitis C virus core-binding protein 1(HCBP1);Aminoacylase-3(ACY-3);Hepatitis C virus core-binding protein 1(HCBP1);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    Plays an important role in deacetylating mercapturic acids in kidney proximal tubules.
    Subcellular Location:
    Apical cell membrane Peripheral membrane protein Cytoplasm Predominantly localized in the apical membrane of cells in the S1 segment. In the proximal straight tubules (S2 and S3 segments) is expressed diffusely throughout the cytoplasm.
    Protein Attributes:
    Sequence length:
    318
    Sequence:
    50:
    MSSLPGSREP | LLRVAVTGGT | HGNEMCGVYL | ARYWLQNPGE | LQRPSFSAMP | 
    100:
    VLANPAATAA | CCRYLDRDLN | RSCTLTFLGS | TATPDDPYEV | KRARELNQLL | 
    150:
    GPKGTGQAFD | FTLDLHNTTA | NTGVCLISES | NISFNLHLCH | YLQRQNPGMP | 
    200:
    CRLFLYEPAG | TETFSVESIS | KNGICLEMGP | QPQGVLRADL | FSRMRALVAS | 
    250:
    ILDFIELFNQ | GMDLPAFEMD | IYRNLGSVDF | PRTADGDLAG | TVHPQLQDHD | 
    300:
    FEPLRPGEPI | FKLFSGEDVL | YEGDSIVYPV | FINEAAYYEK | HVAFLKSEKI | 
    318:
    RVTVPALLRL | TPRSTQTP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    Pfam:
    UniGene:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Aspartoacylase-2
    ELISA Kit for Mouse Aspartoacylase-2
    ELISA Kit for Mouse Aspartoacylase-2
    CLIA Kit for Mouse Aspartoacylase-2
    CLIA Kit for Mouse Aspartoacylase-2
    CLIA Kit for Mouse Aspartoacylase-2
    Polyclonal Antibody for Mouse Aspartoacylase-2
    Polyclonal Antibody for Mouse Aspartoacylase-2
    Polyclonal Antibody for Mouse Aspartoacylase-2
    Monoclonal Antibody for Mouse Aspartoacylase-2
    Monoclonal Antibody for Mouse Aspartoacylase-2
    Monoclonal Antibody for Mouse Aspartoacylase-2
    Protein for Mouse Aspartoacylase-2
    Protein for Mouse Aspartoacylase-2
    Protein for Mouse Aspartoacylase-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The mouse aspartoacylase-3 gene (ACY-3) generates two mRNA isoforms by alternative splicing of 5' untranslated region."
      Chen H. , Peng J. , Huang C.-H.
      Submitted (2001-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: BALB/c.
      tissue: Kidney.
    2. 2.
      "Identification of a novel aspartoacylase homolog (ACY-3) in human and mouse kidneys."
      Huang C.-H. , Chen H. , Peng J. , Chen Y.
      Submitted (2001-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
    3. 3.
      "Structural characterization, tissue distribution, and functional expression of murine aminoacylase III."
      Pushkin A. , Carpenito G. , Abuladze N. , Newman D. , Tsuprun V. , Ryazantsev S. , Motemoturu S. , Sassani P. , Solovieva N. , Dukkipati R. , Kurtz I.
      Am. J. Physiol.286:C848-C856(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;SUBUNIT;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
      strain: C57BL/6.
    4. 4.
      "Cloning and sequence analysis of cDNA encoding hepatitis C virus core-binding protein 1 (HCBP1) from mouse."
      Li K. , Cheng J. , Zhang L. , Wang L. , Lu Y. , Wang G. , Liu Y.
      Submitted (2001-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Kidney.
      tissue: Spleen.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Kidney.
    7. 7.
      "Specificity of aminoacylase III-mediated deacetylation of mercapturic acids."
      Newman D. , Abuladze N. , Scholz K. , Dekant W. , Tsuprun V. , Ryazantsev S. , Bondar G. , Sassani P. , Kurtz I. , Pushkin A.
      Drug Metab. Dispos.35:43-50(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBSTRATE SPECIFICITY
    8. 8.
      "Structural characterization of dimeric murine aminoacylase III."
      Ryazantsev S. , Abuladze N. , Newman D. , Bondar G. , Kurtz I. , Pushkin A.
      FEBS Lett.581:1898-1902(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY ELECTRON MICROSCOPY (16 ANGSTROMS);SUBUNIT
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) IN COMPLEX WITH SUBSTRATES;ZINC-BINDING SITES;SUBUNIT;COFACTOR;MUTAGENESIS OF ARG-63 AND TYR-287
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