Protein name:
Disintegrin and metalloproteinase domain-containing protein 22 (ADAM 22) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with LGI1. Can bind to LGI4.
Function:
Probable ligand for integrin in the brain. This is a non catalytic metalloprotease-like protein. Involved in regulation of cell adhesion and spreading and in inhibition of cell proliferation (By similarity). Neuronal receptor for LGI1.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MQAAAAASFW | LLCVLGTCPL | ARCGRAGVAS | LKGLERGKEN | RFLERQSIIP |
100:
LRLIYRLGGE | DETQHNQLDT | RVRGDPGGPQ | LTHVDKASFR | VDAFGTSFVL |
150:
DVLLNHELLS | SGYVERQIEH | GGKVVENKGG | EHCYYQGQIR | GNPVSFVALS |
200:
TCHGLHGMFY | DGNHTYLIEP | EENEKSQESS | HCHSVYKSRQ | FEFPLDDLPS |
250:
EFQRVNITPP | QFILKPRLKR | RKRQLLRFPR | NVEEETKYIE | LMIVNDHLMF |
300:
KKHRLSVVYT | NTYAKSVVNM | ADVIYKDQLK | TRIVLVAMET | WAADNKFAIS |
350:
ENPLITLREF | MKYRRDFIKE | KADAVHLFSG | SQFESSRSGA | AYIGGICSLL |
400:
RGGGVNEFGK | TDLMAVTLAQ | SLAHNVGIIS | DKRKLASGEC | KCEDTWSGCI |
450:
MGDTGYYLPK | KFTQCNVEEY | HDFLNSGGGA | CLFNKPSKLL | DPPECGNGFI |
500:
ETGEECDCGT | PAECALEGAE | CCKKCTLTQD | SQCSDGLCCK | KCKFQPLGTV |
550:
CREAVNDCDI | REICSGNSSQ | CAPNVHKMDG | YSCDGTQGIC | FGGRCKTRDR |
600:
QCKYIWGQKV | TASDRYCYEK | LNIEGTEKGN | CGKDKDTWTQ | CNKRDVLCGY |
650:
LLCTNIGNIP | RLGELDGEIT | STLVVQQGRT | LNCSGAHVKL | EEDVDLGYVE |
700:
DGTPCGPQMM | CLEHRCLPVA | SFNFSTCSSS | KAGTVCSGNG | VCSNELKCVC |
750:
NRHWTGADCG | THFPHNDDAK | TGITLSGNGV | AGTNIIIGII | AGTILVLALI |
800:
LGITAWGYKN | YREQRQLPQG | DYVKKPGDGD | SFYSDFPPGG | STNSASSSKK |
850:
RSNGLSHSWS | ERIPDTKHIS | DICENGRPRS | NSWQGNMGGN | KKKIRGKRFR |
900:
PRSNSTETLS | PAKSPSSSTG | SIASSRKYPY | PMPPLPDEGK | TAGRQSARLW |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
ELISA Kit for Mouse ADAM 22
ELISA Kit for Mouse ADAM 22
CLIA Kit for Mouse ADAM 22
CLIA Kit for Mouse ADAM 22
Polyclonal Antibody for Mouse ADAM 22
Polyclonal Antibody for Mouse ADAM 22
Monoclonal Antibody for Mouse ADAM 22
Monoclonal Antibody for Mouse ADAM 22
Protein for Mouse ADAM 22
Protein for Mouse ADAM 22
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 17 AND 20)
tissue :
Brain .
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[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 619-904 (ISOFORM 2)
strain :
C57BL/6J .
tissue :
Embryo .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 709-904 (ISOFORMS 1; 2; 3; 4; 5; 6; 7; 8; 9; 10; 11; 12; 13; 14; 15; 16; 17; 18; 19; 20 AND 21);TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH LGI1;MUTAGENESIS OF ASP-509
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH LIGI1 AND LGI4
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[
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[
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH KCNA2; LGI1; DLG2 AND DLG4;SUBCELLULAR LOCATION;TISSUE SPECIFICITY