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Index > Protein center > ADAM23(Gene name) > Human
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  • ADAM23 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 23 (Protein name ),  ADA23_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ADAM23(MDC3);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 23(ADAM 23);
    Alternative:
    Metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3(MDC-3);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Can bind to LGI1 and LGI4 (By similarity). Ligand for integrin alpha-V/beta-3.
    Function:
    May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.
    Subcellular Location:
    Isoform Gamma Secreted
    Protein Attributes:
    Sequence length:
    832
    Sequence:
    50:
    MKPPGSSSRQ | PPLAGCSLAG | ASCGPQRGPA | GSVPASAPAR | TPPCRLLLVL | 
    100:
    LLLPPLAASS | RPRAWGAAAP | SAPHWNETAE | KNLGVLADED | NTLQQNSSSN | 
    150:
    ISYSNAMQKE | ITLPSRLIYY | INQDSESPYH | VLDTKARHQQ | KHNKAVHLAQ | 
    200:
    ASFQIEAFGS | KFILDLILNN | GLLSSDYVEI | HYENGKPQYS | KGGEHCYYHG | 
    250:
    SIRGVKDSKV | ALSTCNGLHG | MFEDDTFVYM | IEPLELVHDE | KSTGRPHIIQ | 
    300:
    KTLAGQYSKQ | MKNLTMERGD | QWPFLSELQW | LKRRKRAVNP | SRGIFEEMKY | 
    350:
    LELMIVNDHK | TYKKHRSSHA | HTNNFAKSVV | NLVDSIYKEQ | LNTRVVLVAV | 
    400:
    ETWTEKDQID | ITTNPVQMLH | EFSKYRQRIK | QHADAVHLIS | RVTFHYKRSS | 
    450:
    LSYFGGVCSR | TRGVGVNEYG | LPMAVAQVLS | QSLAQNLGIQ | WEPSSRKPKC | 
    500:
    DCTESWGGCI | MEETGVSHSR | KFSKCSILEY | RDFLQRGGGA | CLFNRPTKLF | 
    550:
    EPTECGNGYV | EAGEECDCGF | HVECYGLCCK | KCSLSNGAHC | SDGPCCNNTS | 
    600:
    CLFQPRGYEC | RDAVNECDIT | EYCTGDSGQC | PPNLHKQDGY | ACNQNQGRCY | 
    650:
    NGECKTRDNQ | CQYIWGTKAA | GSDKFCYEKL | NTEGTEKGNC | GKDGDRWIQC | 
    700:
    SKHDVFCGFL | LCTNLTRAPR | IGQLQGEIIP | TSFYHQGRVI | DCSGAHVVLD | 
    750:
    DDTDVGYVED | GTPCGPSMMC | LDRKCLQIQA | LNMSSCPLDS | KGKVCSGHGV | 
    800:
    CSNEATCICD | FTWAGTDCSI | RDPVRNLHPP | KDEGPKGPSA | TNLIIGSIAG | 
    832:
    AILVAAIVLG | GTGWGFKNVK | KRRFDPTQQG | PI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    UniGene:
    Pfam:
    SMR:
    MIM:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADAM 23
    ELISA Kit for Human ADAM 23
    CLIA Kit for Human ADAM 23
    CLIA Kit for Human ADAM 23
    Polyclonal Antibody for Human ADAM 23
    Polyclonal Antibody for Human ADAM 23
    Monoclonal Antibody for Human ADAM 23
    Monoclonal Antibody for Human ADAM 23
    Protein for Human ADAM 23
    Protein for Human ADAM 23

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Metalloproteinase-like, disintegrin-like, cysteine-rich proteins MDC2 and MDC3: novel human cellular disintegrins highly expressed in the brain."
      Sagane K. , Ohya Y. , Hasegawa Y. , Tanaka I.
      Biochem. J.334:93-98(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA)
      tissue: Brain.
    2. 2.
      "ADAM 23/MDC3, a human disintegrin that promotes cell adhesion via interaction with the alpha v beta 3 integrin through an RGD-independent mechanism."
      Cal S. , Freije J.M.P. , Lopez J.M. , Takada Y. , Lopez-Otin C.
      Mol. Biol. Cell11:1457-1469(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA);INTERACTION WITH INTEGRIN ALPHA-V/BETA-3;MUTAGENESIS OF GLU-566
      tissue: Brain.
    3. 3.
      "Two novel isoforms of Adam23 expressed in the developmental process of mouse and human brains."
      Sun Y.P. , Deng K.J. , Wang F. , Zhang J. , Huang X. , Qiao S. , Zhao S.
      Gene325:171-178(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS ALPHA; BETA AND GAMMA);TISSUE SPECIFICITY
      tissue: Fetal brain.
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
      tissue: Brain.
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