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Index > Protein center > ADAM7(Gene name) > Human
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  • ADAM7 (Gene name),
  • Disintegrin and metalloproteinase domain-containing protein 7 (Protein name ),  ADAM7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ADAM7(GP83);
    Protein name:
    Disintegrin and metalloproteinase domain-containing protein 7(ADAM 7);
    Alternative:
    Sperm maturation-related glycoprotein GP-83;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May play an important role in male reproduction including sperm maturation and gonadotrope function. This is a non catalytic metalloprotease-like protein.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    754
    Sequence:
    50:
    MLPGCIFLMI | LLIPQVKEKF | ILGVEGQQLV | RPKKLPLIQK | RDTGHTHDDD | 
    100:
    ILKTYEEELL | YEIKLNRKTL | VLHLLRSREF | LGSNYSETFY | SMKGEAFTRH | 
    150:
    PQIMDHCFYQ | GSIVHEYDSA | ASISTCNGLR | GFFRINDQRY | LIEPVKYSDE | 
    200:
    GEHLVFKYNL | RVPYGANYSC | TELNFTRKTV | PGDNESEEDS | KIKGIHDEKY | 
    250:
    VELFIVADDT | VYRRNGHPHN | KLRNRIWGMV | NFVNMIYKTL | NIHVTLVGIE | 
    300:
    IWTHEDKIEL | YSNIETTLLR | FSFWQEKILK | TRKDFDHVVL | LSGKWLYSHV | 
    350:
    QGISYPGGMC | LPYYSTSIIK | DLLPDTNIIA | NRMAHQLGHN | LGMQHDEFPC | 
    400:
    TCPSGKCVMD | SDGSIPALKF | SKCSQNQYHQ | YLKDYKPTCM | LNIPFPYNFH | 
    450:
    DFQFCGNKKL | DEGEECDCGP | AQECTNPCCD | AHTCVLKPGF | TCAEGECCES | 
    500:
    CQIKKAGSIC | RPAKDECDFP | EMCTGHSPAC | PKDQFRVNGF | PCKNSEGYCF | 
    550:
    MGKCPTREDQ | CSELFDDEAI | ESHDICYKMN | TKGNKFGYCK | NKENRFLPCE | 
    600:
    EKDVRCGKIY | CTGGELSSLL | GEDKTYHLKD | PQKNATVKCK | TIFLYHDSTD | 
    650:
    IGLVASGTKC | GEGMVCNNGE | CLNMEKVYIS | TNCPSQCNEN | PVDGHGLQCH | 
    700:
    CEEGQAPVAC | EETLHVTNIT | ILVVVLVLVI | VGIGVLILLV | RYRKCIKLKQ | 
    750:
    VQSPPTETLG | VENKGYFGDE | QQIRTEPILP | EIHFLNKPAS | KDSRGIADPN | 
    754:
    QSAK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    MIM:
    UniGene:
    Pfam:
    String:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human ADAM 7
    ELISA Kit for Human ADAM 7
    ELISA Kit for Human ADAM 7
    CLIA Kit for Human ADAM 7
    CLIA Kit for Human ADAM 7
    CLIA Kit for Human ADAM 7
    Polyclonal Antibody for Human ADAM 7
    Polyclonal Antibody for Human ADAM 7
    Polyclonal Antibody for Human ADAM 7
    Monoclonal Antibody for Human ADAM 7
    Monoclonal Antibody for Human ADAM 7
    Monoclonal Antibody for Human ADAM 7
    Protein for Human ADAM 7
    Protein for Human ADAM 7
    Protein for Human ADAM 7

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    Precision
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    Linearity
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    References
    1. 1.
      "Expression of human ADAM7 (GP-83)."
      Lin Y.C. , Lee Y.M. , Sun G.H. , Liu H.W.
      Submitted (1999-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Epididymis.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Testis.
    3. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Testis.
    4. 5.
      "A ADAM-like cDNA sequence identified in cDNA library of human epididymis."
      Liu H.W. , Lin Y.C. , Sun G.H.
      Submitted (1998-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 167-754 (ISOFORM 1)
      tissue: Epididymis.
    5. 6.
      "Analysis of the disintegrin-metalloproteinases family reveals ADAM29 and ADAM7 are often mutated in melanoma."
      Wei X. , Moncada-Pazos A. , Cal S. , Soria-Valles C. , Gartner J. , Rudloff U. , Lin J.C. , Rosenberg S.A. , Lopez-Otin C. , Samuels Y.
      Hum. Mutat.32:E2148-E2175(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INVOLVEMENT IN CUTANEOUS MELANOMA;VARIANTS SER-14; CYS-31; SER-36; TYR-106; PRO-173; ALA-180; TYR-243; GLU-302; ILE-359; GLU-533; LEU-593; LYS-639 AND ASN-703;CHARACTERIZATION OF VARIANTS TYR-243; ILE-359; LYS-639 AND ASN-703
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