Protein name:
Adseverin ;
Alternative:
Scinderin ;Gelsolin-like protein ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Ca(2+)-dependent actin filament-severing protein that is presumed to have a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane. In vitro, also has barbed end capping and nucleating activities in the presence of Ca(2+). Regulates chondrocyte proliferation and differentiation. MAP kinases p38 and ERK1/2 mediate the adseverin-induced accelerated differentiation of non-hypertrophic chondrocytes (By similarity). Isoform 2 fails to nucleate actin polymerization, although it severs and caps actin filaments in a Ca(2+)-dependent manner.
Subcellular Location:
Cytoplasm
cytoskeleton
Protein Attributes:
50:
MAQELQHPEF | ARAGQQAGLQ | VWRVEKLELV | PVPQGAYGDF | YVGDAYLVLH |
100:
TTKSSRGFSY | RLHFWLGKEC | SQDESTAAAI | FTVQMDDYLG | GKPVQSRELQ |
150:
GYESTDFVGY | FKGGLKYKAG | GVASGLNHVL | TNDLTAKRLL | HVKGRRVVRA |
200:
TEVPLSWESF | NKGDCFIIDL | GTEIYQWCGS | SCNKYERLKA | SQVAIGIRDN |
250:
ERKGRSQLIV | VEEGSEPSEL | MKVLGRKPEL | PDGDNDDDVV | ADISNRKMAK |
300:
LYMVSDASGS | MKVTLVAEEN | PFSMGMLLSE | ECFILDHGAA | KQIFVWKGKN |
350:
ANPQERKTAM | KTAEEFLQKM | KYSTNTQIQV | LPEGGETPIF | KQFFKDWKDK |
400:
DQSDGFGKVY | ITEKVAQIKQ | IPFDASKLHS | SPQMAAQHNM | VDDGSGGVEI |
450:
WRVENSGRVQ | IDPSSYGEFY | GGDCYIILYT | YPRGQIIYTW | QGANATRDEL |
500:
TMSAFLTVQL | DRSLGGQAVQ | VRVSQGKEPA | HLLSLFKDKP | LIIYKNGTSK |
550:
KEGQAPAPPT | RLFQVRRNLA | SITRIVEVDV | DANSLNSNDT | FVLKLPRNNG |
600:
FIWIGKGASQ | EEEKGAEYVA | DVLKCKASRI | QEGKEPEEFW | NSLGGRGDYQ |
650:
TSPLLETRAE | DHPPRLYGCS | NKTGRFIIEE | VPGEFTQDDL | AEDDVMLLDA |
700:
WEQIFIWIGK | DANEVEKKES | VKSAKMYLET | DPSGRDKRTP | IVIIKQGHEP |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Chicken
Mouse
Bovine
ELISA Kit for Mouse Adseverin
ELISA Kit for Mouse Adseverin
ELISA Kit for Mouse Adseverin
ELISA Kit for Mouse Adseverin
ELISA Kit for Mouse Adseverin
CLIA Kit for Mouse Adseverin
CLIA Kit for Mouse Adseverin
CLIA Kit for Mouse Adseverin
CLIA Kit for Mouse Adseverin
CLIA Kit for Mouse Adseverin
Polyclonal Antibody for Mouse Adseverin
Polyclonal Antibody for Mouse Adseverin
Polyclonal Antibody for Mouse Adseverin
Polyclonal Antibody for Mouse Adseverin
Polyclonal Antibody for Mouse Adseverin
Monoclonal Antibody for Mouse Adseverin
Monoclonal Antibody for Mouse Adseverin
Monoclonal Antibody for Mouse Adseverin
Monoclonal Antibody for Mouse Adseverin
Monoclonal Antibody for Mouse Adseverin
Protein for Mouse Adseverin
Protein for Mouse Adseverin
Protein for Mouse Adseverin
Protein for Mouse Adseverin
Protein for Mouse Adseverin
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];ALTERNATIVE SPLICING
strain :
C57BL/6 .
tissue :
Lymph node .
2.
"The transcriptional landscape of the mammalian genome."
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Ovary .
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Kidney .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-102 AND TYR-599;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .