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Index > Protein center > FDX1(Gene name) > Human
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  • FDX1 (Gene name),
  • Adrenodoxin, mitochondrial (Protein name ),  ADX_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    FDX1(ADX);
    Protein name:
    Adrenodoxin, mitochondrial;
    Alternative:
    Ferredoxin-1;Adrenal ferredoxin;Hepatoredoxin;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Participates in the synthesis of thyroid hormones. Transfers electrons from adrenodoxin reductase to the cholesterol side chain cleavage cytochrome P450.
    Subcellular Location:
    Mitochondrion matrix
    Protein Attributes:
    Sequence length:
    184
    Sequence:
    50:
    MAAAGGARLL | RAASAVLGGP | AGRWLHHAGS | RAGSSGLLRN | RGPGGSAEAS | 
    100:
    RSLSVSARAR | SSSEDKITVH | FINRDGETLT | TKGKVGDSLL | DVVVENNLDI | 
    150:
    DGFGACEGTL | ACSTCHLIFE | DHIYEKLDAI | TDEENDMLDL | AYGLTDRSRL | 
    184:
    GCQICLTKSM | DNMTVRVPET | VADARQSIDV | GKTS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    UniGene:
    KEGG:
    String:
    Pfam:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Adrenodoxin, mitochondrial
    ELISA Kit for Human Adrenodoxin, mitochondrial
    ELISA Kit for Human Adrenodoxin, mitochondrial
    ELISA Kit for Human Adrenodoxin, mitochondrial
    ELISA Kit for Human Adrenodoxin, mitochondrial
    ELISA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    CLIA Kit for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Polyclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Monoclonal Antibody for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial
    Protein for Human Adrenodoxin, mitochondrial

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    References
    1. 1.
      "Cloning and structure of the human adrenodoxin gene."
      Chang C.-Y. , Wu D.-A. , Lai C.-C. , Miller W.L. , Chung B.-C.
      DNA7:609-615(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    2. 2.
      "Human adrenodoxin: cloning of three cDNAs and cycloheximide enhancement in JEG-3 cells."
      Picado-Leonard J. , Voutilainen R. , Kao L.-C. , Chung B.-C. , Strauss J.F. III , Miller W.L.
      J. Biol. Chem.263:3240-3244(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Molecular cloning and sequence analysis of human placental ferredoxin."
      Mittal S. , Zhu Y.-Z. , Vickery L.E.
      Arch. Biochem. Biophys.264:383-391(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    4. 4.
      "Structure, sequence, chromosomal location, and evolution of the human ferredoxin gene family."
      Chang C.-Y. , Wu D.-A. , Mohandas T.K. , Chung B.-C.
      DNA Cell Biol.9:205-212(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    5. 5.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    6. 6.
      NHLBI resequencing and genotyping service (RS&G)
      Submitted (2007-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
      tissue: Placenta.
    8. 8.
      "Electrochemical behaviour of human adrenodoxin on a pyrolytic graphite electrode."
      Johnson D. , Norman S. , Tuckey R.C. , Martin L.L.
      Bioelectrochemistry59:41-47(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CYCLIC VOLTAMMETRY
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis."
      Sheftel A.D. , Stehling O. , Pierik A.J. , Elsasser H.P. , Muhlenhoff U. , Webert H. , Hobler A. , Hannemann F. , Bernhardt R. , Lill R.
      Proc. Natl. Acad. Sci. U.S.A.107:11775-11780(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    12. 12.
      "1H NMR spectra of vertebrate [2Fe-2S] ferredoxins. Hyperfine resonances suggest different electron delocalization patterns from plant ferredoxins."
      Skjeldal L. , Markley J.L. , Coghlan V.M. , Vickery L.E.
      Biochemistry30:9078-9083(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR
    13. 13.
      "Crystal structure of human ferredoxin-1 (FDX1) in complex with iron-sulfur cluster."
      Structural genomics consortium (SGC)
      Submitted (2010-11) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.54 ANGSTROMS) OF 61-184 IN COMPLEX WITH IRON-SULFUR CLUSTER;COFACTOR
    14. 14.
      "Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system."
      Strushkevich N. , MacKenzie F. , Cherkesova T. , Grabovec I. , Usanov S. , Park H.W.
      Proc. Natl. Acad. Sci. U.S.A.108:10139-10143(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 62-175 IN COMPLEX WITH IRON-SULFUR CLUSTER AND CYP11A1;FUNCTION;COFACTOR;INTERACTION WITH CYP11A1
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