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Index > Protein center > AEBP1(Gene name) > Human
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  • AEBP1 (Gene name),
  • Adipocyte enhancer-binding protein 1 (Protein name ),  AEBP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    AEBP1(ACLP);
    Protein name:
    Adipocyte enhancer-binding protein 1(AE-binding protein 1);
    Alternative:
    Aortic carboxypeptidase-like protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with GNG5, NFKBIA, MAPK1, MAPK3 and PTEN (By similarity). May interact with calmodulin (By similarity). Binds to DNA in vitro.
    Function:
    May positively regulate MAP-kinase activity in adipocytes, leading to enhanced adipocyte proliferation and reduced adipocyte differentiation (By similarity). May also positively regulate NF-kappa-B activity in macrophages by promoting the phosphorylation and subsequent degradation of I-kappa-B-alpha (NFKBIA), leading to enhanced macrophage inflammatory responsiveness (By similarity). Can act as a transcriptional repressor.
    Subcellular Location:
    Isoform 2 Cytoplasm Nucleus
    Protein Attributes:
    Sequence length:
    1158
    Sequence:
    50:
    MAAVRGAPLL | SCLLALLALC | PGGRPQTVLT | DDEIEEFLEG | FLSELEPEPR | 
    100:
    EDDVEAPPPP | EPTPRVRKAQ | AGGKPGKRPG | TAAEVPPEKT | KDKGKKGKKD | 
    150:
    KGPKVPKESL | EGSPRPPKKG | KEKPPKATKK | PKEKPPKATK | KPKEKPPKAT | 
    200:
    KKPKEKPPKA | TKKPPSGKRP | PILAPSETLE | WPLPPPPSPG | PEELPQEGGA | 
    250:
    PLSNNWQNPG | EETHVEAREH | QPEPEEETEQ | PTLDYNDQIE | REDYEDFEYI | 
    300:
    RRQKQPRPPP | SRRRRPERVW | PEPPEEKAPA | PAPEERIEPP | VKPLLPPLPP | 
    350:
    DYGDGYVIPN | YDDMDYYFGP | PPPQKPDAER | QTDEEKEELK | KPKKEDSSPK | 
    400:
    EETDKWAVEK | GKDHKEPRKG | EELEEEWTPT | EKVKCPPIGM | ESHRIEDNQI | 
    450:
    RASSMLRHGL | GAQRGRLNMQ | TGATEDDYYD | GAWCAEDDAR | TQWIEVDTRR | 
    500:
    TTRFTGVITQ | GRDSSIHDDF | VTTFFVGFSN | DSQTWVMYTN | GYEEMTFHGN | 
    550:
    VDKDTPVLSE | LPEPVVARFI | RIYPLTWNGS | LCMRLEVLGC | SVAPVYSYYA | 
    600:
    QNEVVATDDL | DFRHHSYKDM | RQLMKVVNEE | CPTITRTYSL | GKSSRGLKIY | 
    650:
    AMEISDNPGE | HELGEPEFRY | TAGIHGNEVL | GRELLLLLMQ | YLCREYRDGN | 
    700:
    PRVRSLVQDT | RIHLVPSLNP | DGYEVAAQMG | SEFGNWALGL | WTEEGFDIFE | 
    750:
    DFPDLNSVLW | GAEERKWVPY | RVPNNNLPIP | ERYLSPDATV | STEVRAIIAW | 
    800:
    MEKNPFVLGA | NLNGGERLVS | YPYDMARTPT | QEQLLAAAMA | AARGEDEDEV | 
    850:
    SEAQETPDHA | IFRWLAISFA | SAHLTLTEPY | RGGCQAQDYT | GGMGIVNGAK | 
    900:
    WNPRTGTIND | FSYLHTNCLE | LSFYLGCDKF | PHESELPREW | ENNKEALLTF | 
    950:
    MEQVHRGIKG | VVTDEQGIPI | ANATISVSGI | NHGVKTASGG | DYWRILNPGE | 
    1000:
    YRVTAHAEGY | TPSAKTCNVD | YDIGATQCNF | ILARSNWKRI | REIMAMNGNR | 
    1050:
    PIPHIDPSRP | MTPQQRRLQQ | RRLQHRLRLR | AQMRLRRLNA | TTTLGPHTVP | 
    1100:
    PTLPPAPATT | LSTTIEPWGL | IPPTTAGWEE | SETETYTEVV | TEFGTEVEPE | 
    1150:
    FGTKVEPEFE | TQLEPEFETQ | LEPEFEEEEE | EEKEEEIATG | QAFPFTTVET | 
    1158:
    YTVNFGDF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human AE-binding protein 1
    Cat.:
    E7716h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human AE-binding protein 1
    Cat.:
    E7716r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human AE-binding protein 1
    Cat.:
    E7716m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AE-binding protein 1
    Cat.:
    U7716m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human AE-binding protein 1
    Cat.:
    U7716r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human AE-binding protein 1
    Cat.:
    U7716h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human AE-binding protein 1
    Cat.:
    P7716Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AE-binding protein 1
    Cat.:
    P7716Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human AE-binding protein 1
    Cat.:
    P7716Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human AE-binding protein 1
    Monoclonal Antibody for Human AE-binding protein 1
    Monoclonal Antibody for Human AE-binding protein 1
    Protein for Human AE-binding protein 1
    Protein for Human AE-binding protein 1
    Protein for Human AE-binding protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Aortic carboxypeptidase-like protein, a novel protein with discoidin and carboxypeptidase-like domains, is up-regulated during vascular smooth muscle cell differentiation."
      Layne M.D. , Endege W.O. , Jain M.K. , Yet S.-F. , Hsieh C.-M. , Chin M.T. , Perrella M.A. , Blanar M.A. , Haber E. , Lee M.-E.
      J. Biol. Chem.273:15654-15660(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Aortic smooth muscle.
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    3. 3.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT GLU-1133
      tissue: Aortic endothelium.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    6. 7.
      "A cDNA cloning of human AEBP1 from primary cultured osteoblasts and its expression in a differentiating osteoblastic cell line."
      Ohno I. , Hashimoto J. , Shimizu K. , Takaoka K. , Ochi T. , Matsubara K. , Okubo K.
      Biochem. Biophys. Res. Commun.228:411-414(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 314-1158 (ISOFORM 1);TISSUE SPECIFICITY
      tissue: Cancellous bone.
    7. 8.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-528 AND ASN-922
      tissue: Liver.
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