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Index > Protein center > AEBP2(Gene name) > Human
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  • AEBP2 (Gene name),
  • Zinc finger protein AEBP2 (Protein name ),  AEBP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AEBP2;
    Protein name:
    Zinc finger protein AEBP2;
    Alternative:
    Adipocyte enhancer-binding protein 2(AE-binding protein 2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Self-associates. Interacts with EED, EZH2, RBBP4 and SUZ12. Component of the PRC2/EED-EZH1 complex, which includes EED, EZH1, SUZ12, RBBP4 and AEBP2 (By similarity). May also interact with RBBP7.
    Function:
    DNA-binding transcriptional repressor. May interact with and stimulate the activity of the PRC2 complex, which methylates 'Lys-9' and 'Lys-27' residues of histone H3.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    517
    Sequence:
    50:
    MAAAITDMAD | LEELSRLSPL | PPGSPGSAAR | GRAEPPEEEE | EEEEEEEEAE | 
    100:
    AEAVAALLLN | GGSGGGGGGG | GGGVGGGEAE | TMSEPSPESA | SQAGEDEDEE | 
    150:
    EDDEEEEDES | SSSGGGEEES | SAESLVGSSG | GSSSDETRSL | SPGAASSSSG | 
    200:
    DGDGKEGLEE | PKGPRGSQGG | GGGGSSSSSV | VSSGGDEGYG | TGGGGSSATS | 
    250:
    GGRRGSLEMS | SDGEPLSRMD | SEDSISSTIM | DVDSTISSGR | STPAMMNGQG | 
    300:
    STTSSSKNIA | YNCCWDQCQA | CFNSSPDLAD | HIRSIHVDGQ | RGGVFVCLWK | 
    350:
    GCKVYNTPST | SQSWLQRHML | THSGDKPFKC | VVGGCNASFA | SQGGLARHVP | 
    400:
    THFSQQNSSK | VSSQPKAKEE | SPSKAGMNKR | RKLKNKRRRS | LPRPHDFFDA | 
    450:
    QTLDAIRHRA | ICFNLSAHIE | SLGKGHSVVF | HSTVIAKRKE | DSGKIKLLLH | 
    500:
    WMPEDILPDV | WVNESERHQL | KTKVVHLSKL | PKDTALLLDP | NIYRTMPQKR | 
    517:
    LKRTLIRKVF | NLYLSKQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Zinc finger protein AEBP2
    ELISA Kit for Human Zinc finger protein AEBP2
    ELISA Kit for Human Zinc finger protein AEBP2
    CLIA Kit for Human Zinc finger protein AEBP2
    CLIA Kit for Human Zinc finger protein AEBP2
    CLIA Kit for Human Zinc finger protein AEBP2
    Polyclonal Antibody for Human Zinc finger protein AEBP2
    Polyclonal Antibody for Human Zinc finger protein AEBP2
    Polyclonal Antibody for Human Zinc finger protein AEBP2
    Monoclonal Antibody for Human Zinc finger protein AEBP2
    Monoclonal Antibody for Human Zinc finger protein AEBP2
    Monoclonal Antibody for Human Zinc finger protein AEBP2
    Protein for Human Zinc finger protein AEBP2
    Protein for Human Zinc finger protein AEBP2
    Protein for Human Zinc finger protein AEBP2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Teratocarcinoma.
      tissue: Uterus.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Eye.
      tissue: Uterus.
    4. 4.
      Totoki Y. , Toyoda A. , Takeda T. , Sakaki Y. , Tanaka A. , Yokoyama S. , Ohara O. , Nagase T. , Kikuno R.F.
      Submitted (2005-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 61-517 (ISOFORM 1)
      tissue: Brain.
    5. 5.
      "Role of histone H3 lysine 27 methylation in Polycomb-group silencing."
      Cao R. , Wang L. , Wang H. , Xia L. , Erdjument-Bromage H. , Tempst P. , Jones R.S. , Zhang Y.
      Science298:1039-1043(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH EED; EZH2; RBBP4; RBBP7 AND SUZ12
    6. 6.
      "SUZ12 is required for both the histone methyltransferase activity and the silencing function of the EED-EZH2 complex."
      Cao R. , Zhang Y.
      Mol. Cell15:57-67(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SELF-ASSOCIATION;INTERACTION WITH EED; EZH2; RBBP4 AND SUZ12
    7. 7.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18 AND SER-24;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206; SER-210 AND SER-211;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    11. 11.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    12. 12.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-18; SER-24 AND SER-390;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206 AND SER-390;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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