Eif2c1 ELISA Kit for Mouse(Mus musculus) | EIAab.comEif2c1 ELISA Kit for Mouse(Mus musculus) | EIAab.com

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Eif2c1 (Gene name),

Protein argonaute-1 (Protein name ), AGO1_MOUSE from NCBI database.

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General Annotation

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Antigen Annotation

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3D

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Predicted Eptitope

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Vaild Sequence

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Related Databases

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Gene name:

Eif2c1(Ago1);

Protein name:

Protein argonaute-1(Argonaute1;mAgo1);

Alternative:

Piwi/argonaute family protein meIF2C1(eIF-2C 1);Eukaryotic translation initiation factor 2C 1(eIF-2C 1;eIF2C 1);Piwi/argonaute family protein meIF2C1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Interacts with DDB1, DDX5, DDX6, DHX30, DHX36, DDX47, DICER1, EIF2C2/AGO2, ELAVL1, HNRNPF, IGF2BP1, ILF3, IMP8, MATR3, MOV10, PABPC1, PRMT5, RBM4, SART3, TNRC6B, UPF1 and YBX1. Associates with polysomes and messenger ribonucleoproteins (mNRPs).

Function:

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. May also be required for transcriptional gene silencing (TGS) of promoter regions which are complementary to bound short antigene RNAs (agRNAs).

Subcellular Location:

Cytoplasm P-body

Protein Attributes:

Sequence length:

857

Sequence:

50:

MEAGPSGAAA | GAYLPPLQQV | FQAPRRPGIG | TVGKPIKLLA | NYFEVDIPKI |

100:

DVYHYEVDIK | PDKCPRRVNR | EVVEYMVQHF | KPQIFGDRKP | VYDGKKNIYT |

150:

VTALPIGNER | VDFEVTIPGE | GKDRIFKVSI | KWLAIVSWRM | LHEALVSGQI |

200:

PVPLESVQAL | DVAMRHLASM | RYTPVGRSFF | SPPEGYYHPL | GGGREVWFGF |

250:

HQSVRPAMWK | MMLNIDVSAT | AFYKAQPVIE | FMCEVLDIRN | IDEQPKPLTD |

300:

SQRVRFTKEI | KGLKVEVTHC | GQMKRKYRVC | NVTRRPASHQ | TFPLQLESGQ |

350:

TVECTVAQYF | KQKYNLQLKY | PHLPCLQVGQ | EQKHTYLPLE | VCNIVAGQRC |

400:

IKKLTDNQTS | TMIKATARSA | PDRQEEISRL | MKNASYNLDP | YIQEFGIKVK |

450:

DDMTEVTGRV | LPAPILQYGG | RNRAIATPNQ | GVWDMRGKQF | YNGIEIKVWA |

500:

IACFAPQKQC | REEVLKNFTD | QLRKISKDAG | MPIQGQPCFC | KYAQGADSVE |

550:

PMFRHLKNTY | SGLQLIIVIL | PGKTPVYAEV | KRVGDTLLGM | ATQCVQVKNV |

600:

VKTSPQTLSN | LCLKINVKLG | GINNILVPHQ | RSAVFQQPVI | FLGADVTHPP |

650:

AGDGKKPSIT | AVVGSMDAHP | SRYCATVRVQ | RPRQEIIEDL | SYMVRELLIQ |

700:

FYKSTRFKPT | RIIFYRDGVP | EGQLPQILHY | ELLAIRDACI | KLEKDYQPGI |

750:

TYIVVQKRHH | TRLFCADKNE | RIGKSGNIPA | GTTVDTNITH | PFEFDFYLCS |

800:

HAGIQGTSRP | SHYYVLWDDN | RFTADELQIL | TYQLCHTYVR | CTRSVSIPAP |

850:

AYYARLVAFR | ARYHLVDKEH | DSGEGSHISG | QSNGRDPQAL | AKAVQVHQDT |

857:

LRTMYFA

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

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Related Databases

SMR:

UniGene:

Pfam:

KEGG:

STRING:

10090.ENSMUSP00000095498

String:

Uniprot:

FOR

ELISA Kit for Mouse Argonaute1

ELISA Kit for Mouse Argonaute1

CLIA Kit for Mouse Argonaute1

CLIA Kit for Mouse Argonaute1

Polyclonal Antibody for Mouse Argonaute1

Polyclonal Antibody for Mouse Argonaute1

Monoclonal Antibody for Mouse Argonaute1

Monoclonal Antibody for Mouse Argonaute1

Protein for Mouse Argonaute1

Protein for Mouse Argonaute1

R&D Technical Data

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Precision

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Recovery

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

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Linearity

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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors."
Doi N. , Zenno S. , Ueda R. , Ohki-Hamazaki H. , Ui-Tei K. , Saigo K.
Curr. Biol.13:41-46(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.

"Essential and overlapping functions for mammalian Argonautes in microRNA silencing."
Su H. , Trombly M.I. , Chen J. , Wang X.
Genes Dev.23:304-317(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION

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