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Index > Protein center > Eif2c3(Gene name) > Mouse
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  • Eif2c3 (Gene name),
  • Protein argonaute-3 (Protein name ),  AGO3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    Eif2c3(Ago3);
    Protein name:
    Protein argonaute-3(Argonaute3;mAgo3);
    Alternative:
    Piwi/argonaute family protein meIF2C3(eIF-2C 3);Eukaryotic translation initiation factor 2C 3(eIF-2C 3;eIF2C 3);Piwi/argonaute family protein meIF2C3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with EIF4B, IMP8, PRMT5 and TNRC6B.
    Function:
    Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs.
    Subcellular Location:
    Cytoplasm P-body
    Protein Attributes:
    Sequence length:
    860
    Sequence:
    50:
    MEIGSAGPIG | AQPLFIVPRR | PGYGTMGKPI | KLLANCFQVE | IPKIDVYLYE | 
    100:
    VDIKPDKCPR | RVNREVVDSM | VQHFKVTIFG | DRRPVYDGKR | SLYTANPLPV | 
    150:
    ATTGVDLDVT | LPGEGGKDRP | FKVSVKFVSR | VSWHLLHEAL | AGGTLPEPLE | 
    200:
    LDKPVSTNPV | HAVDVVLRHL | PSMKYTPVGR | SFFSAPEGYD | HPLGGGREVW | 
    250:
    FGFHQSVRPA | MWKMMLNIDV | SATAFYKAQP | VIQFMCEVLD | IHNIDEQPRP | 
    300:
    LTDSHRVKFT | KEIKGLKVEV | THCGTMRRKY | RVCNVTRRPA | SHQTFPLQLE | 
    350:
    NGQTVERTVA | QYFREKYTLQ | LKYPHLPCLQ | VGQEQKHTYL | PLEVCNIVAG | 
    400:
    QRCIKKLTDN | QTSTMIKATA | RSAPDRQEEI | SRLVRSANYE | TDPFVQEFQF | 
    450:
    KVRDEMAHVT | GRVLPAPMLQ | YGGRNRTVAT | PSHGVWDMRG | KQFHTGVEIK | 
    500:
    MWAIACFATQ | RQCREEILKG | FTDQLRKISK | DAGMPIQGQP | CFCKYAQGAD | 
    550:
    SVEPMFRHLK | NTYSGLQLII | VILPGKTPVY | AEVKRVGDTL | LGMATQCVQV | 
    600:
    KNVIKTSPQT | LSNLCLKINV | KLGGINNILV | PHQRPSVFQQ | PVIFLGADVT | 
    650:
    HPPAGDGKKP | SIAAVVGSMD | AHPSRYCATV | RVQRPRQEII | QDLASMVREL | 
    700:
    LIQFYKSTRF | KPTRIIFYRD | GVSEGQFRQV | LYYELLAIRE | ACISLEKDYQ | 
    750:
    PGITYIVVQK | RHHTRLFCAD | RTERVGRSGN | IPAGTTVDTD | ITHPYEFDFY | 
    800:
    LCSHAGIQGT | SRPSHYHVLW | DDNFFTADEL | QLLTYQLCHT | YVRCTRSVSI | 
    850:
    PAPAYYAHLV | AFRARYHLVD | KEHDSAEGSH | VSGQSNGRDP | QALAKAVQIH | 
    860:
    QDTLRTMYFA | 
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Argonaute3
    ELISA Kit for Mouse Argonaute3
    ELISA Kit for Mouse Argonaute3
    ELISA Kit for Mouse Argonaute3
    CLIA Kit for Mouse Argonaute3
    CLIA Kit for Mouse Argonaute3
    CLIA Kit for Mouse Argonaute3
    CLIA Kit for Mouse Argonaute3
    Polyclonal Antibody for Mouse Argonaute3
    Polyclonal Antibody for Mouse Argonaute3
    Polyclonal Antibody for Mouse Argonaute3
    Polyclonal Antibody for Mouse Argonaute3
    Monoclonal Antibody for Mouse Argonaute3
    Monoclonal Antibody for Mouse Argonaute3
    Monoclonal Antibody for Mouse Argonaute3
    Monoclonal Antibody for Mouse Argonaute3
    Protein for Mouse Argonaute3
    Protein for Mouse Argonaute3
    Protein for Mouse Argonaute3
    Protein for Mouse Argonaute3

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors."
      Doi N. , Zenno S. , Ueda R. , Ohki-Hamazaki H. , Ui-Tei K. , Saigo K.
      Curr. Biol.13:41-46(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: NOD.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    6. 6.
      "Essential and overlapping functions for mammalian Argonautes in microRNA silencing."
      Su H. , Trombly M.I. , Chen J. , Wang X.
      Genes Dev.23:304-317(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
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