Gene name:
Ahrr (Kiaa1234) ;
Protein name:
Aryl hydrocarbon receptor repressor (AhR repressor;AhRR) ;
Alternative:
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with ARNT, ANKRA2, HDAC4 and HDAC5.
Function:
Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Subcellular Location:
Cytoplasm
Nucleus
Predominantly in the nuclear compartment. First cytoplasmic, translocates into the nuclear compartment upon interaction with ARNT in the cytoplasmic compartment.
Protein Attributes:
50:
MMIPSGECTY | AGRKRRKPIQ | KRRLTMGAEK | SNPSKRHRDR | LNTELDHLAS |
100:
LLPFSPDIIS | KLDKLSVLRL | SVSYLRVKSF | FQALQETCVW | SAPALSPEEH |
150:
SYRGFPVQEG | RLLLESLNGF | ALVVSAEGMI | FYASATIVDY | LGFHQTDVMH |
200:
QNIYDYIHVD | DRQDFCRQLH | WAMDPPQVVF | GQSPHADTDN | TVLGKLLRAQ |
250:
EGGKGLPSEY | SAFLTRCFIC | RVRCLLDSTS | GFLTMQFQGK | LKFLFGQKKK |
300:
TPSGTALPPR | LSLFCIVAPV | LPSVTEMKMK | STFLKAKHRA | DIVVTMDSRA |
350:
KAVTSLCESE | LHPKLNYLAG | KSNGENGISL | FRGQTDRSHW | ARALARSSCL |
400:
CLRGGPDLLD | PKGTSGDREE | EDQKHILRRS | PGAWGQREMH | KYSYGLETPV |
450:
HLRHLNWSTE | QRSQESTTKL | TRQPSKNEPS | TCLVPHGSCV | PYPGSQGMLS |
500:
ASNMASFRDS | LDHPTGAYCS | QMNRPLSDIH | QGQVDPSTCH | ISQGSLGSRI |
550:
PLTGMQRFTA | RGFSTEDAKL | PSLPVTIGTP | CNPVLSLDVP | IKMENESGSQ |
600:
DIVEASTTSC | LWLGTSDMAR | GHLVGFPARM | HLKTEPDYRQ | QACTPHLGHG |
650:
MLGTNPYSRD | TVGSCREHAP | LYSAHCTCLD | PEPPHHLFMC | SHSESQHPSL |
700:
DQDCRAPIVK | REPLDSPSWA | APGQVTVPRM | FPKSASKTVI | PSKGSDGIFL |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Mouse AhR repressor
ELISA Kit for Mouse AhR repressor
ELISA Kit for Mouse AhR repressor
CLIA Kit for Mouse AhR repressor
CLIA Kit for Mouse AhR repressor
CLIA Kit for Mouse AhR repressor
Polyclonal Antibody for Mouse AhR repressor
Polyclonal Antibody for Mouse AhR repressor
Polyclonal Antibody for Mouse AhR repressor
Monoclonal Antibody for Mouse AhR repressor
Monoclonal Antibody for Mouse AhR repressor
Monoclonal Antibody for Mouse AhR repressor
Protein for Mouse AhR repressor
Protein for Mouse AhR repressor
Protein for Mouse AhR repressor
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH ARNT;SUBCELLULAR LOCATION;INDUCTION
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C57BL/6 .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain :
C57BL/6J .
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[
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
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DNA Res.11:205-218(2004)
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PubMed ]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 92-701 (ISOFORM 3)
tissue :
Fetal brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH ANKRA2; HDAC4 AND HDAC5