Gene name:
AKR1C1(DDH;DDH1);
Protein name:
Aldo-keto reductase family 1 member C1;
Alternative:
Chlordecone reductase homolog HAKRC;1.1.1.149;20-alpha-hydroxysteroid dehydrogenase(20-alpha-HSD);High-affinity hepatic bile acid-binding protein(HBAB);Dihydrodiol dehydrogenase 1/2(DD1/DD2);1.3.1.20;Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase);1.1.1.112;Indanol dehydrogenase);
Organism:
Human (Homo sapiens).
General Annotation
Function:
Converts progesterone to its inactive form, 20-alpha-dihydroxyprogesterone (20-alpha-OHP). In the liver and intestine, may have a role in the transport of bile. May have a role in monitoring the intrahepatic bile acid concentration. Has a low bile-binding ability. May play a role in myelin formation.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MDSKYQCVKL | NDGHFMPVLG | FGTYAPAEVP | KSKALEATKL | AIEAGFRHID |
100:
SAHLYNNEEQ | VGLAIRSKIA | DGSVKREDIF | YTSKLWCNSH | RPELVRPALE |
150:
RSLKNLQLDY | VDLYLIHFPV | SVKPGEEVIP | KDENGKILFD | TVDLCATWEA |
200:
VEKCKDAGLA | KSIGVSNFNR | RQLEMILNKP | GLKYKPVCNQ | VECHPYFNQR |
250:
KLLDFCKSKD | IVLVAYSALG | SHREEPWVDP | NSPVLLEDPV | LCALAKKHKR |
300:
TPALIALRYQ | LQRGVVVLAK | SYNEQRIRQN | VQVFEFQLTS | EEMKAIDGLN |
323:
RNVRYLTLDI | FAGPPNYPFS | DEY
Vaild Sequence:
Related Databases
Uniprot:
