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Index > Protein center > Akap12(Gene name) > Mouse
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  • Akap12 (Gene name),
  • A-kinase anchor protein 12 (Protein name ),  AKA12_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Akap12(Gag12;Ssecks);
    Protein name:
    A-kinase anchor protein 12(AKAP-12);
    Alternative:
    Src-suppressed C kinase substrate(SSeCKS);Germ cell lineage protein gercelin;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Binds to dimeric RII-alpha regulatory subunit of PKC.
    Function:
    Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    1684
    Sequence:
    50:
    MGAGSSTEQR | SPEQPAESDT | PSELELSGHG | PAAEASGAAG | DPADADPATK | 
    100:
    LPQKNGQLSA | VNGVAEQEDV | HVQEESQDGQ | EEEVTVEDVG | QRESEDVKEK | 
    150:
    DRAKEMAASS | TVVEDITKDE | QEETPEIIEQ | IPASESNVEE | MAQAAESQAN | 
    200:
    DVGFKKVFKF | VGFKFTVKKD | KNEKSDTVQL | LTVKKDEGEG | AEASVGAGDH | 
    250:
    QEPGVETVGE | SASKESELKQ | STEKQEGTLK | QAQSSTEIPL | QAESGQGTEE | 
    300:
    EAAKDGEENR | EKEPTKPLES | PTSPVSNETT | SSFKKFFTHG | WAGWRKKTSF | 
    350:
    KKPKEDDLET | SEKRKEQEAE | KVDEEEGEKT | EPAPAEEQEP | AEGTDQARLS | 
    400:
    ADYEKVELPL | EDQVGDLEAL | SEKCAPLATE | VFDEKTEAHQ | EVVAEVHVST | 
    450:
    VEKMTKGQGG | AEVEGDVVVE | GSGESLPPEK | LAETQEVPQE | AEPVEELMKT | 
    500:
    KEVCVSGGDH | TQLTDLSPEE | KMLPKHPEGI | VSEVEMLSSQ | ERIKVQGSPL | 
    550:
    KKLFSSSGLK | KLSGKKQKGK | RGGGGGDEEP | GEYQHIQTES | PESADEQKGE | 
    600:
    SSASSPEEPE | EIACLEKGPS | EAPQEAEAEE | GATSDGEKKR | EGITPWASFK | 
    650:
    KMVTPKKRVR | RPSESDKEEE | LDKVKSATLS | STESTASGMQ | DEVRAVGEEQ | 
    700:
    RSEEPKRRVD | TSVSWEALIC | VGSSKKRARK | ASSSDDEGGP | RTLGGDGHRA | 
    750:
    EEASKDKEAD | ALPASTQEQD | QAHGSSSPEP | AGSPSEGEGV | STWESFKRLV | 
    800:
    TPRKKSKSKL | EERAEDSGAE | QLASEIEPSR | EESWVSIKKF | IPGRRKKRAD | 
    850:
    GKQEQAAVED | SGPGEINEDD | PDVPAVVPLS | EYDAVEREKL | EAQRAQENVE | 
    900:
    LPQLKGAVYV | SEELSKTLVH | TVSVAVIDGT | RAVTSAEERS | PSWISASMTE | 
    950:
    PLEHAEGVAT | PPVGEVTEKD | ITAEATPALA | QTLPGGKDAH | DDIVTSEVDF | 
    1000:
    TSEAVTAAET | TEALRAEELT | EASGAEETTD | MVSAVSQLSD | SPDTTEEATP | 
    1050:
    VQEVEGGMLD | TEEQERQTQA | VLQAVADKVK | EDSQVPATQT | LQRAGPKALE | 
    1100:
    KVEEVEEDSE | VLATEKEKDV | VPEGPVQEAE | TEHLAQGSET | VQATPESLEV | 
    1150:
    PEVTEDVDRA | TTCQVIKHQQ | LMEQAVAPES | SETLTDSETN | GSTPLADSDT | 
    1200:
    PNGTQQDETV | DSQDSNAIAA | VKQSQVTEEE | AAAAQTEGPS | TPSSFPAQEE | 
    1250:
    HREKPGRDVL | EPTQALAAGA | VPILAKAEVG | QEGEAGQFDG | EKVKDGQCVK | 
    1300:
    ELEVPVHTGP | NSQKTADLTR | DSEVMEVARC | QETESNEEQS | ISPEKREMGT | 
    1350:
    DVEKEETETK | TEQASEEHEQ | ETAAPEHEGT | HPKPVLTADM | PHSERGKALG | 
    1400:
    SLEGSPSLPD | QDKADCIEVQ | VQSSDTPVTQ | TTEAVKKVEE | TVATSEMDES | 
    1450:
    LECAGAQSLP | AEKLSETGGY | GTLQHGEDTV | PQGPESQAES | IPIIVTPAPE | 
    1500:
    SILHSDLQRE | VSASQKQRSD | EDNKPDAGPD | AAGKESAARE | KILRAEPEIL | 
    1550:
    ELESKSNKIV | QSVIQTAVDQ | FARTETAPET | HASDLQNQVP | VMQADSQGAQ | 
    1600:
    QMLDKDESDL | QVSPQDGTLS | AVAQEGLAVS | DSSEGMSKAS | EMITTLAVES | 
    1650:
    ASVKESVEKL | PLQCKDEKEH | AADGPQHQSL | AKAEADASGN | LTKESPDTNG | 
    1684:
    PKLTEEGDAL | KEEMNKAQTE | EDDLQEPKGD | LTES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    KEGG:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse AKAP-12
    ELISA Kit for Mouse AKAP-12
    ELISA Kit for Mouse AKAP-12
    CLIA Kit for Mouse AKAP-12
    CLIA Kit for Mouse AKAP-12
    CLIA Kit for Mouse AKAP-12
    Polyclonal Antibody for Mouse AKAP-12
    Polyclonal Antibody for Mouse AKAP-12
    Polyclonal Antibody for Mouse AKAP-12
    Monoclonal Antibody for Mouse AKAP-12
    Monoclonal Antibody for Mouse AKAP-12
    Monoclonal Antibody for Mouse AKAP-12
    Protein for Mouse AKAP-12
    Protein for Mouse AKAP-12
    Protein for Mouse AKAP-12

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Gene trap insertion reveals two open reading frames in the mouse SSeCKS gene: the form predominantly detected in the nervous system is suppressed by the insertion while the other, specific of the testis, remains expressed."
      Camus A. , Mesbah K. , Rallu M. , Babinet C. , Barra J.
      Mech. Dev.105:79-91(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);TISSUE SPECIFICITY
      tissue: Testis.
    2. 2.
      "Induction of Src-suppressed C kinase substrate (SSeCKS) in vascular endothelial cells by bacterial lipopolysaccharide."
      Kitamura H. , Okita K. , Fujikura D. , Mori K. , Iwanaga T. , Saito M.
      J. Histochem. Cytochem.50:245-255(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      strain: BALB/c.
      tissue: Testis.
    3. 3.
      "Mouse testicular cell specific gene, GAG12."
      Nishina Y. , Motoda Y.
      Submitted (1999-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
      tissue: Testis.
    4. 4.
      "Molecular cloning and characterization of the mouse germ cell lineage protein cDNA, gercelin, encoding the cytoplasmic AKAP, Gercelin / SSeCKS and the potential germ cell-specific nuclear antigen, GENA."
      Tsuchida J. , Tanaka H. , Yomogida K. , Nozaki M. , Maeda N. , Matsui Y. , Nishimune Y.
      Submitted (2001-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Testis.
    5. 5.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-605 (ISOFORM 1)
      strain: C57BL/6J.
      tissue: Eye.
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 139-1684 (ISOFORMS 1/2)
      strain: FVB/N.
      tissue: Mammary tumor.
    7. 7.
      "Phosphoproteomic analysis of the developing mouse brain."
      Ballif B.A. , Villen J. , Beausoleil S.A. , Schwartz D. , Gygi S.P.
      Mol. Cell. Proteomics3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic brain.
    8. 8.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-467;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    9. 9.
      "A differential phosphoproteomic analysis of retinoic acid-treated P19 cells."
      Smith J.C. , Duchesne M.A. , Tozzi P. , Ethier M. , Figeys D.
      J. Proteome Res.6:3174-3186(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-682; SER-683 AND SER-684;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Teratocarcinoma.
    10. 10.
      "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
      Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-353;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic fibroblast.
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