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Index > Protein center > Akap12(Gene name) > Rat
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  • Akap12 (Gene name),
  • A-kinase anchor protein 12 (Protein name ),  AKA12_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Akap12;
    Protein name:
    A-kinase anchor protein 12(AKAP-12);
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Binds to dimeric RII-alpha regulatory subunit of PKC.
    Function:
    Anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) and protein kinase C (PKC).
    Subcellular Location:
    Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    1687
    Sequence:
    50:
    MGAGSSTEQR | SPEQPAGSDT | PSELVLSGHG | PAAEASGAAG | DPADADPATK | 
    100:
    LPQKNGQLST | VNGVAEQGDV | HVQEENQEGQ | EEEVVDEDVG | QRESEDVREK | 
    150:
    DRVEEMAANS | TAVEDITKDG | QEETSEIIEQ | IPASESNVEE | MVQPAESQAN | 
    200:
    DVGFKKVFKF | VGFKFTVKKD | KNEKSDTVQL | LTVKKDEGEG | AEASVGAGDH | 
    250:
    QEPSVETAVG | ESASKESELK | QSTEKQEGTL | KQEQSSTEIP | LQAESDQAAE | 
    300:
    EEAKDEGEEK | QEKEPTKSPE | SPSSPVSSET | TSSFKKFFTH | GWAGWRKKTS | 
    350:
    FKKSKEDDLE | TAEKRKEQEA | EKVDEEEKEK | TEPASEEQEP | AEDTDQARLS | 
    400:
    ADYEKVELPL | EDQVGDLEAS | SEEKCAPLAT | EVFDEKMEAH | QEVVAEVHVS | 
    450:
    TVEKTEEEQG | GGGEAEGGVV | VEGTGESLPP | EKLAEPQEVP | QEAEPAEELM | 
    500:
    KSREMCVSGG | DHTQLTDLSP | EEKTLPKHPE | GIVSEVEMLS | SQERIKVQGS | 
    550:
    PLKKLFSSSG | LKKLSGKKQK | GKRGGGGDEE | PGEYQHIHTE | SPESADEQKG | 
    600:
    ESSASSPEEP | EETTCLEKGP | LEAPQDGEAE | EGTTSDGEKK | REGITPWASF | 
    650:
    KKMVTPKKRV | RRPSESDKEE | ELEKVKSATL | SSTDSTVSEM | QDEVKTVGEE | 
    700:
    QKPEEPKRRV | DTSVSWEALI | CVGSSKKRAR | KASSSDDEGG | PRTLGGDSHR | 
    750:
    AEEASKDKEA | GTDAVPASTQ | EQDQAQGSSS | PEPAGSPSEG | EGVSTWESFK | 
    800:
    RLVTPRKKSK | SKLEEKAEDS | SVEQLSTEIE | PSREESWVSI | KKFIPGRRKK | 
    850:
    RADGKQEQAT | VEDSGPVEIN | EDDPDVPAVV | PLSEYDAVER | EKMEAQGNAE | 
    900:
    LPQLLGAVYV | SEELSKTLVH | TVSVAVIDGT | RAVTSVEERS | PSWISASVTE | 
    950:
    PLEHTAGEAM | PPVEEVTEKD | IIAEETPVLT | QTLPEGKDAH | DDMVTSEVDF | 
    1000:
    TSEAVTATET | SEALRTEEVT | EASGAEETTD | MVSAVSQLTD | SPDTTEEATP | 
    1050:
    VQEVEGGVLD | TEEEERQTQA | ILQAVADKVK | EESQVPATQT | VQRTGSKALE | 
    1100:
    KVEEVEEDSE | VLASEKEKDV | MPKGPVQEAG | AEHLAQGSET | GQATPESLEV | 
    1150:
    PEVTADVDHV | ATCQVIKLQQ | LMEQAVAPES | SETLTDSETN | GSTPLADSDT | 
    1200:
    ADGTQQDETI | DSQDSKATAA | VRQSQVTEEE | AATAQKEEPS | TLPNNVPAQE | 
    1250:
    EHGEEPGRDV | LEPTQQELAA | AAVPVLAKTE | VGQEGEVDWL | DGEKVKEEQE | 
    1300:
    VFVHSGPNSQ | KAADVTYDSE | VMGVAGCQEK | ESTEVQSLSL | EEGEMETDVE | 
    1350:
    KEKRETKPEQ | VSEEGEQETA | APEHEGTYGK | PVLTLDMPSS | ERGKALGSLG | 
    1400:
    GSPSLPDQDK | AGCIEVQVQS | LDTTVTQTAE | AVEKVIETVV | ISETGESPEC | 
    1450:
    VGAHLLPAEK | SSATGGHWTL | QHAEDTVPLG | PESQAESIPI | IVTPAPESTL | 
    1500:
    HPDLQGEISA | SQRERSEEED | KPDAGPDADG | KESTAIEKVL | KAEPEILELE | 
    1550:
    SKSNKIVLNV | IQTAVDQFAR | TETAPETHAY | DSQTQVPAMQ | ADSQGAQQML | 
    1600:
    DKNESCQDET | PSAAAQRGLA | SPDRSGGMGS | ASEMLAALAV | ESAGVKVSIE | 
    1650:
    KLPPQPKDQK | EHAADGPQLQ | SLAQAEASAS | GNLTKESPDT | NGPKLTEEGD | 
    1687:
    APKVEVQEEE | MSTKSVKENK | AQAEEDLQEP | KGDLAES
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat AKAP-12
    ELISA Kit for Rat AKAP-12
    ELISA Kit for Rat AKAP-12
    CLIA Kit for Rat AKAP-12
    CLIA Kit for Rat AKAP-12
    CLIA Kit for Rat AKAP-12
    Polyclonal Antibody for Rat AKAP-12
    Polyclonal Antibody for Rat AKAP-12
    Polyclonal Antibody for Rat AKAP-12
    Monoclonal Antibody for Rat AKAP-12
    Monoclonal Antibody for Rat AKAP-12
    Monoclonal Antibody for Rat AKAP-12
    Protein for Rat AKAP-12
    Protein for Rat AKAP-12
    Protein for Rat AKAP-12

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of a major protein kinase C-binding protein and substrate in rat embryo fibroblasts. Decreased expression in transformed cells."
      Chapline C. , Mousseau B. , Ramsay K. , Duddy S. , Li Y. , Kiley S.C. , Jaken S.
      J. Biol. Chem.271:6417-6422(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PHOSPHORYLATION
    2. 2.
      "Multiple promoters direct expression of three AKAP12 isoforms with distinct subcellular and tissue distribution profiles."
      Streb J.W. , Kitchen C.M. , Gelman I.H. , Miano J.M.
      J. Biol. Chem.279:56014-56023(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3)
    3. 3.
      "Cross-species sequence analysis reveals multiple charged residue-rich domains that regulate nuclear/cytoplasmic partitioning and membrane localization of a kinase anchoring protein 12 (SSeCKS/Gravin)."
      Streb J.W. , Miano J.M.
      J. Biol. Chem.280:28007-28014(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
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