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Index > Protein center > AKAP7(Gene name) > Human
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  • AKAP7 (Gene name),
  • A-kinase anchor protein 7 isoforms alpha and beta (Protein name ),  AKA7A_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AKAP7(AKAP18;AKAP18);
    Protein name:
    A-kinase anchor protein 7 isoforms alpha and beta(AKAP-7 isoforms alpha and beta);
    Alternative:
    Protein kinase A-anchoring protein 7 isoforms alpha/beta(PRKA7 isoforms alpha/beta);A-kinase anchor protein 18 kDa(AKAP 18);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds cAMP-dependent protein kinase (PKA).
    Function:
    Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel.
    Subcellular Location:
    Isoform Beta Apical cell membrane Lipid-anchor Targeted predominantly to the apical membrane.
    Protein Attributes:
    Sequence length:
    104
    Sequence:
    50:
    MGQLCCFPFS | RDEGKISELE | SSSSAVLQRY | SKDIPSWSSG | EKNGGEPDDA | 
    100:
    ELVRLSKRLV | ENAVLKAVQQ | YLEETQNKNK | PGEGSSVKTE | AADQNGNDNE | 
    104:
    NNRK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    MIM:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    ELISA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    CLIA Kit for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Polyclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Monoclonal Antibody for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta
    Protein for Human AKAP-7 isoforms alpha and beta

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    Linearity
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    References
    1. 1.
      "A novel lipid-anchored A-kinase anchoring protein facilitates cAMP-responsive membrane events."
      Fraser I.D.C. , Tavalin S.J. , Lester L.B. , Langeberg L.K. , Westphal A.M. , Dean R.A. , Marrion N.V. , Scott J.D.
      EMBO J.17:2261-2272(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MYRISTOYLATION AT GLY-2;PALMITOYLATION AT CYS-5 AND CYS-6
      tissue: Brain.
    2. 2.
      "Alternative splicing regulates the subcellular localization of A-kinase anchoring protein 18 isoforms."
      Trotter K.W. , Fraser I.D.C. , Scott G.K. , Stutts M.J. , Scott J.D. , Milgram S.L.
      J. Cell Biol.147:1481-1492(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA);FUNCTION;SUBCELLULAR LOCATION
      tissue: Lung.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM BETA)
      tissue: Colon.
    4. 4.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA)
      tissue: Adrenal cortex.
      tissue: Hippocampus.
      tissue: Lung.
    7. 7.
      "The A-kinase anchoring protein 15 regulates feedback inhibition of the epithelial Na+ channel."
      Bengrine A. , Li J. , Awayda M.S.
      FASEB J.21:1189-1201(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH PRKCA;MUTAGENESIS OF 2-GLY--CYS-6
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