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Index > Protein center > AKAP2(Gene name) > Human
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  • AKAP2 (Gene name),
  • A-kinase anchor protein 2 (Protein name ),  AKAP2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AKAP2(KIAA0920;PRKA2);
    Protein name:
    A-kinase anchor protein 2(AKAP-2);
    Alternative:
    Protein kinase A-anchoring protein 2(PRKA2);AKAP-KL;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds to regulatory subunit (RII) of protein kinase A. May be involved in establishing polarity in signaling systems or in integrating PKA-RII isoforms with downstream effectors to capture, amplify and focus diffuse, trans-cellular signals carried by cAMP.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    859
    Sequence:
    50:
    MEIEVSVAEC | KSVPGITSTP | HPMDHPSAFY | SPPHNGLLTD | HHESLDNDVA | 
    100:
    REIRYLDEVL | EANCCDSAVD | GTYNGTSSPE | PGAVVLVGGL | SPPVHEATQP | 
    150:
    EPTERTASRQ | APPHIELSNS | SPDPMAEAER | TNGHSPSQPR | DALGDSLQVP | 
    200:
    VSPSSTTSSR | CSSRDGEFTL | TTLKKEAKFE | LRAFHEDKKP | SKLFEDDEHE | 
    250:
    KEQYCIRKVR | PSEEMLELEK | ERRELIRSQA | VKKNPGIAAK | WWNPPQEKTI | 
    300:
    EEQLDEEHLE | SHKKYKERKE | RRAQQEQLLL | QKQLQQQQQQ | PPSQLCTAPA | 
    350:
    SSHERASMID | KAKEDIVTEQ | IDFSAARKQF | QLMENSRQAV | AKGQSTPRLF | 
    400:
    SIKPFYRPLG | SVNSDKPLTN | PRPPSVGGPP | EDSGASAAKG | QKSPGALETP | 
    450:
    SAAGSQGNTA | SQGKEGPYSE | PSKRGPLSKL | WAEDGEFTSA | RAVLTVVKDD | 
    500:
    DHGILDQFSR | SVNVSLTQEE | LDSGLDELSV | RSQDTTVLET | LSNDFSMDNI | 
    550:
    SDSGASNETT | NALQENSLAD | FSLPQTPQTD | NPSEGRGEGV | SKSFSDHGFY | 
    600:
    SPSSTLGDSP | LVDDPLEYQA | GLLVQNAIQQ | AIAEQVDKAV | SKTSRDGAEQ | 
    650:
    QGPEATVEEA | EAAAFGSEKP | QSMFEPPQVS | SPVQEKRDVL | PKILPAEDRA | 
    700:
    LRERGPPQPL | PAVQPSGPIN | MEETRPEGSY | FSKYSEAAEL | RSTASLLATQ | 
    750:
    ESDVMVGPFK | LRSRKQRTLS | MIEEEIRAAQ | EREEELKRQR | QVLQSTQSPR | 
    800:
    TKNAPSLPSR | TCYKTAPGKI | EKVKPPPSPT | TEGPSLQPDL | APEEAAGTQR | 
    850:
    PKNLMQTLME | DYETHKSKRR | ERMDDSSVLE | ATRVNRRKSA | LALRWEAGIY | 
    859:
    ANQEEEDNE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    MIM:
    String:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human AKAP-2
    ELISA Kit for Human AKAP-2
    ELISA Kit for Human AKAP-2
    CLIA Kit for Human AKAP-2
    CLIA Kit for Human AKAP-2
    CLIA Kit for Human AKAP-2
    Polyclonal Antibody for Human AKAP-2
    Polyclonal Antibody for Human AKAP-2
    Polyclonal Antibody for Human AKAP-2
    Monoclonal Antibody for Human AKAP-2
    Monoclonal Antibody for Human AKAP-2
    Monoclonal Antibody for Human AKAP-2
    Protein for Human AKAP-2
    Protein for Human AKAP-2
    Protein for Human AKAP-2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Homo sapiens AKAP-2 complete cDNA sequence."
      Schuetze N. , Reichel S. , Ruecker N. , Lechner A. , Eulert J. , Jakob F.
      Submitted (2000-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.6:63-70(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Brain.
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);VARIANT SER-561
      tissue: Placenta.
      tissue: Small intestine.
    4. 4.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 4 AND 5);VARIANT SER-561
      tissue: Brain.
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 539-859 (ISOFORMS 1/3/4)
      tissue: Brain.
    8. 8.
      "The paralemmin protein family: identification of paralemmin-2, an isoform differentially spliced to AKAP2/AKAP-KL, and of palmdelphin, a more distant cytosolic relative."
      Hu B. , Copeland N.G. , Gilbert D.J. , Jenkins N.A. , Kilimann M.W.
      Biochem. Biophys. Res. Commun.285:1369-1376(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 3)
      tissue: Muscle.
    9. 9.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-393;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-121; SER-152; SER-393; SER-631; SER-720 AND SER-748;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-152; SER-393; SER-461 AND SER-720;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    14. 14.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-152; SER-393 AND SER-748;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-152; SER-393; SER-720 AND SER-748;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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