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Index > Protein center > Aktip(Gene name) > Mouse
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  • Aktip (Gene name),
  • AKT-interacting protein (Protein name ),  AKTIP_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Aktip(Fif;Ft1;Fts);
    Protein name:
    AKT-interacting protein;
    Alternative:
    Fused toes protein;FT1;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Component of the FTS/Hook/FHIP complex (FHF complex), composed of AKTIP/FTS, FAM160A2, and one or more members of the Hook family of proteins HOOK1, HOOK2, and HOOK3. May interact directly with HOOK1, HOOK2 and HOOK3. The FHF complex associates with the homotypic vesicular sorting complex (the HOPS complex). Also interacts with AKT1.
    Function:
    Component of the FTS/Hook/FHIP complex (FHF complex). The FHF complex may function to promote vesicle trafficking and/or fusion via the homotypic vesicular protein sorting complex (the HOPS complex). Regulates apoptosis by enhancing phosphorylation and activation of AKT1. Increases release of TNFSF6 via the AKT1/GSK3B/NFATC1 signaling cascade.
    Subcellular Location:
    Cytoplasm Cell membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    292
    Sequence:
    50:
    MNPLWSMSAG | SVRKRAEGEE | KTLAGDVKTS | PPRSAPKKQL | PSIPKNALPI | 
    100:
    AKPTSPAPAA | QSTNGTHASY | GPFYLEYSLL | AEFTLVVKQK | LPGVYVQPSY | 
    150:
    RSALVWFGVI | FIRHGLYQDG | VFKFTVYIPD | NYPDGDCPRL | LFDIPVFHPL | 
    200:
    VDPTSGELDV | KRAFAKWRRN | HNHIWQVLMY | ARRVFYKIDT | TSPLNPEAAV | 
    250:
    LYEKDIQLFK | SKVVDSVKVC | TARLFDQPKI | EDPYAISFSP | WNPSVHDEAR | 
    292:
    EKMLTQKKPD | EQHNKSVHVA | GLSWVKPGSV | QPFSKEEKTV | AT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    String:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse AKT-interacting protein
    Cat.:
    E14178h
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    Packing:
    96T
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    ELISA Kit for Mouse AKT-interacting protein
    Cat.:
    E14178m
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Mouse AKT-interacting protein
    Cat.:
    E14178r
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    Packing:
    96T
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    ELISA Kit for Mouse AKT-interacting protein
    Cat.:
    E14178c
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AKT-interacting protein
    Cat.:
    U14178h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AKT-interacting protein
    Cat.:
    U14178m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AKT-interacting protein
    Cat.:
    U14178r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse AKT-interacting protein
    Cat.:
    U14178c
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse AKT-interacting protein
    Cat.:
    P14178Rb-m
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse AKT-interacting protein
    Cat.:
    P14178Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse AKT-interacting protein
    Cat.:
    P14178Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse AKT-interacting protein
    Monoclonal Antibody for Mouse AKT-interacting protein
    Monoclonal Antibody for Mouse AKT-interacting protein
    Monoclonal Antibody for Mouse AKT-interacting protein
    Monoclonal Antibody for Mouse AKT-interacting protein
    Protein for Mouse AKT-interacting protein
    Protein for Mouse AKT-interacting protein
    Protein for Mouse AKT-interacting protein
    Protein for Mouse AKT-interacting protein

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    References
    1. 1.
      "Ft1, a novel gene related to ubiquitin conjugating enzymes, is deleted in the Fused toes mouse mutation."
      Lesche R. , Peetz A. , van der Hoeven F. , Ruether U.
      Mamm. Genome8:879-883(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
      strain: C57BL/6.
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Amnion.
      tissue: Visual cortex.
    3. 3.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Mammary tumor.
    5. 5.
      "Programmed cell death is affected in the novel mouse mutant Fused toes (Ft)."
      van der Hoeven F. , Schimmang T. , Volkmann A. , Mattei M.-G. , Kyewski B. , Ruether U.
      Development120:2601-2607(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISEASE
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