Protein name:
RNA demethylase ALKBH5 ;
Alternative:
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 5 ;Alkylated DNA repair protein alkB homolog 5 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A) RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes. Requires molecular oxygen, alpha-ketoglutarate and iron. Demethylation of m6A mRNA affects mRNA processing and export and is required for spermatogenesis.
Subcellular Location:
Nucleus speckle
Protein Attributes:
50:
MAAASGYTDL | REKLKSMTSR | DNYKAGSREA | AAAAAAAVAA | AAAAAAAAEP |
100:
YPVSGTTKRK | YQEDSDPERS | DYEEHQLQKE | EEARKVKSGI | RQIRLFSQDE |
150:
CSKIEARIDE | VVSRAEKGLY | NEHTVDRAPL | RNKYFFGEGY | TYGAQLQKRG |
200:
PGQERLYPPG | DVDEIPEWVH | QLVIQKLVEH | RVIPEGFVNS | AVINDYQPGG |
250:
CIVSHVDPIH | IFERPIVSVS | FFSDSALCFG | CKFQFKPIRV | SEPVLSLPVR |
300:
RGSVTVLSGY | AADEITHCIR | PQDIKERRAV | IILRKTRLDA | PRLETKSLSS |
350:
STLPPSYASD | RLSGNTRDPA | LKPKRSHRKA | DPDAAHRPRI | LEMDKEENRR |
395:
SVLLPTHRRR | GSFSSENYWR | KSYESSEDCP | EAASSPTRKV | KMRRH
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Human
Mouse
ELISA Kit for Rat RNA demethylase ALKBH5
ELISA Kit for Rat RNA demethylase ALKBH5
ELISA Kit for Rat RNA demethylase ALKBH5
ELISA Kit for Rat RNA demethylase ALKBH5
CLIA Kit for Rat RNA demethylase ALKBH5
CLIA Kit for Rat RNA demethylase ALKBH5
CLIA Kit for Rat RNA demethylase ALKBH5
CLIA Kit for Rat RNA demethylase ALKBH5
Polyclonal Antibody for Rat RNA demethylase ALKBH5
Polyclonal Antibody for Rat RNA demethylase ALKBH5
Polyclonal Antibody for Rat RNA demethylase ALKBH5
Polyclonal Antibody for Rat RNA demethylase ALKBH5
Monoclonal Antibody for Rat RNA demethylase ALKBH5
Monoclonal Antibody for Rat RNA demethylase ALKBH5
Monoclonal Antibody for Rat RNA demethylase ALKBH5
Monoclonal Antibody for Rat RNA demethylase ALKBH5
Protein for Rat RNA demethylase ALKBH5
Protein for Rat RNA demethylase ALKBH5
Protein for Rat RNA demethylase ALKBH5
Protein for Rat RNA demethylase ALKBH5
R&D Technical Data
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Precision
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Recovery
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Linearity
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more...
Nature428:493-521(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .