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Index > Protein center > IGFALS(Gene name) > Human
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  • IGFALS (Gene name),
  • Insulin-like growth factor-binding protein complex acid labile subunit (Protein name ),  ALS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    IGFALS(ALS);
    Protein name:
    Insulin-like growth factor-binding protein complex acid labile subunit(ALS);
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.
    Function:
    Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.
    Subcellular Location:
    Secreted extracellular space
    Protein Attributes:
    Sequence length:
    605
    Sequence:
    50:
    MALRKGGLAL | ALLLLSWVAL | GPRSLEGADP | GTPGEAEGPA | CPAACVCSYD | 
    100:
    DDADELSVFC | SSRNLTRLPD | GVPGGTQALW | LDGNNLSSVP | PAAFQNLSSL | 
    150:
    GFLNLQGGQL | GSLEPQALLG | LENLCHLHLE | RNQLRSLALG | TFAHTPALAS | 
    200:
    LGLSNNRLSR | LEDGLFEGLG | SLWDLNLGWN | SLAVLPDAAF | RGLGSLRELV | 
    250:
    LAGNRLAYLQ | PALFSGLAEL | RELDLSRNAL | RAIKANVFVQ | LPRLQKLYLD | 
    300:
    RNLIAAVAPG | AFLGLKALRW | LDLSHNRVAG | LLEDTFPGLL | GLRVLRLSHN | 
    350:
    AIASLRPRTF | KDLHFLEELQ | LGHNRIRQLA | ERSFEGLGQL | EVLTLDHNQL | 
    400:
    QEVKAGAFLG | LTNVAVMNLS | GNCLRNLPEQ | VFRGLGKLHS | LHLEGSCLGR | 
    450:
    IRPHTFTGLS | GLRRLFLKDN | GLVGIEEQSL | WGLAELLELD | LTSNQLTHLP | 
    500:
    HRLFQGLGKL | EYLLLSRNRL | AELPADALGP | LQRAFWLDVS | HNRLEALPNS | 
    550:
    LLAPLGRLRY | LSLRNNSLRT | FTPQPPGLER | LWLEGNPWDC | GCPLKALRDF | 
    600:
    ALQNPSAVPR | FVQAICEGDD | CQPPAYTYNN | ITCASPPEVV | GLDLRDLSEA | 
    605:
    HFAPC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    Pfam:
    SMR:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human ALS
    Cat.:
    E10593m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human ALS
    Cat.:
    E10593h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human ALS
    Cat.:
    E10593r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALS
    Cat.:
    U10593m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALS
    Cat.:
    U10593h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human ALS
    Cat.:
    U10593r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human ALS
    Cat.:
    P10593Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ALS
    Cat.:
    P10593Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human ALS
    Cat.:
    P10593Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human ALS
    Monoclonal Antibody for Human ALS
    Monoclonal Antibody for Human ALS
    Protein for Human ALS
    Protein for Human ALS
    Protein for Human ALS

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    Linearity
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    References
    1. 1.
      "Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex."
      Leong S.R. , Baxter R.C. , Camerato T. , Dai J. , Wood W.I.
      Mol. Endocrinol.6:870-876(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);PARTIAL PROTEIN SEQUENCE
      tissue: Liver.
    2. 2.
      "Conservation of a growth hormone-responsive promoter element in the human and mouse acid-labile subunit genes."
      Suwanichkul A. , Boisclair Y.R. , Olney R.C. , Durham S.K. , Powell D.R.
      Endocrinology141:833-838(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
      tissue: Thymus.
    4. 4.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "High molecular weight insulin-like growth factor binding protein complex. Purification and properties of the acid-labile subunit from human serum."
      Baxter R.C. , Martin J.L. , Beniac V.A.
      J. Biol. Chem.264:11843-11848(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 28-35
    6. 6.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-368 AND ASN-515
      tissue: Plasma.
    7. 7.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-368
      tissue: Liver.
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