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Index > Protein center > AMACR(Gene name) > Human
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  • AMACR (Gene name),
  • Alpha-methylacyl-CoA racemase (Protein name ),  AMACR_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    AMACR;
    Protein name:
    Alpha-methylacyl-CoA racemase;
    Alternative:
    2-methylacyl-CoA racemase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Racemization of 2-methyl-branched fatty acid CoA esters. Responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers.
    Subcellular Location:
    Peroxisome Mitochondrion
    Protein Attributes:
    Sequence length:
    382
    Sequence:
    50:
    MALQGISVVE | LSGLAPGPFC | AMVLADFGAR | VVRVDRPGSR | YDVSRLGRGK | 
    100:
    RSLVLDLKQP | RGAAVLRRLC | KRSDVLLEPF | RRGVMEKLQL | GPEILQRENP | 
    150:
    RLIYARLSGF | GQSGSFCRLA | GHDINYLALS | GVLSKIGRSG | ENPYAPLNLL | 
    200:
    ADFAGGGLMC | ALGIIMALFD | RTRTGKGQVI | DANMVEGTAY | LSSFLWKTQK | 
    250:
    LSLWEAPRGQ | NMLDGGAPFY | TTYRTADGEF | MAVGAIEPQF | YELLIKGLGL | 
    300:
    KSDELPNQMS | MDDWPEMKKK | FADVFAEKTK | AEWCQIFDGT | DACVTPVLTF | 
    350:
    EEVVHHDHNK | ERGSFITSEE | QDVSPRPAPL | LLNTPAIPSF | KRDPFIGEHT | 
    382:
    EEILEEFGFS | REEIYQLNSD | KIIESNKVKA | SL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    Pfam:
    SMR:
    UniGene:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    E0993h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
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    ELISA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    E0993m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    E0993r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    U0993m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    U0993h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Alpha-methylacyl-CoA racemase
    Cat.:
    U0993r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Cat.:
    P0993Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Cat.:
    P0993Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Cat.:
    P0993Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Monoclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Monoclonal Antibody for Human Alpha-methylacyl-CoA racemase
    Protein for Human Alpha-methylacyl-CoA racemase
    Protein for Human Alpha-methylacyl-CoA racemase
    Protein for Human Alpha-methylacyl-CoA racemase

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Citations
    References
    1. 1.
      "Mitochondrial and peroxisomal targeting of 2-methylacyl-CoA racemase in humans."
      Amery L. , Fransen M. , De Nys K. , Mannaerts G.P. , Van Veldhoven P.P.
      J. Lipid Res.41:1752-1759(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS ASP-175; SER-201; THR-261 AND LYS-277;SUBCELLULAR LOCATION;MICROBODY TARGETING
    2. 2.
      "Mutations in the gene encoding peroxisomal alpha-methylacyl-CoA racemase cause adult-onset sensory motor neuropathy."
      Ferdinandusse S. , Denis S. , Clayton P.T. , Graham A. , Rees J.E. , Allen J.T. , McLean B.N. , Brown A.Y. , Vreken P. , Waterham H.R. , Wanders R.J.A.
      Nat. Genet.24:188-191(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT AMACRD PRO-52;VARIANT CBAS4 PRO-107;VARIANTS SER-201 AND LYS-277;CHARACTERIZATION OF VARIANT AMACRD PRO-52;CHARACTERIZATION OF VARIANT CBAS4 PRO-107
    3. 3.
      "A variant of the alpha-methyl-acyl-CoA racemase gene created by a deletion in exon 5 and its expression in prostate cancer."
      Mubiru J.N. , Valente A.J. , Troyer D.A.
      Prostate65:117-123(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4);VARIANTS SER-201 AND LYS-277
      tissue: Prostate cancer.
    4. 4.
      "Human alpha-methylacyl-CoA racemase cDNA sequence."
      Albers C. , Schmitz W. , Conzelmann E.
      Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANTS MET-9; ASP-175; SER-201; THR-261 AND LYS-277
    5. 5.
      "Expression of alpha-methylacyl-CoA racemase spliced variants in normal and malignant prostate tissue."
      Ouyang B. , Leung Y.-K. , Wang V. , Chung E. , Levin L. , Bracken B. , Cheng L. , Ho S.-M.
      Submitted (2008-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);VARIANT MET-9
    6. 6.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT MET-9
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Salivary gland.
    8. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA];VARIANT MET-9
    9. 10.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);VARIANT MET-9
      tissue: Kidney.
    10. 11.
      "Purification and characterization of an alpha-methylacyl-CoA racemase from human liver."
      Schmitz W. , Albers C. , Fingerhut R. , Conzelmann E.
      Eur. J. Biochem.231:815-822(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
      tissue: Liver.
    11. 12.
      "Liver disease caused by failure to racemize trihydroxycholestanoic acid: gene mutation and effect of bile acid therapy."
      Setchell K.D.R. , Heubi J.E. , Bove K.E. , O'Connell N.C. , Brewsaugh T. , Steinberg S.J. , Moser A. , Squires R.H. Jr.
      Gastroenterology124:217-232(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CBAS4 PRO-52
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