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Index > Protein center > AMN(Gene name) > Human
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  • AMN (Gene name),
  • Protein amnionless (Protein name ),  AMNLS_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AMN(UNQ513/PRO1028);
    Protein name:
    Protein amnionless;
    Alternative:

    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CUBN/cubilin.
    Function:
    Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    453
    Sequence:
    50:
    MGVLGRVLLW | LQLCALTQAV | SKLWVPNTDF | DVAANWSQNR | TPCAGGAVEF | 
    100:
    PADKMVSVLV | QEGHAVSDML | LPLDGELVLA | SGAGFGVSDV | GSHLDCGAGE | 
    150:
    PAVFRDSDRF | SWHDPHLWRS | GDEAPGLFFV | DAERVPCRHD | DVFFPPSASF | 
    200:
    RVGLGPGASP | VRVRSISALG | RTFTRDEDLA | VFLASRAGRL | RFHGPGALSV | 
    250:
    GPEDCADPSG | CVCGNAEAQP | WICAALLQPL | GGRCPQAACH | SALRPQGQCC | 
    300:
    DLCGAVVLLT | HGPAFDLERY | RARILDTFLG | LPQYHGLQVA | VSKVPRSSRL | 
    350:
    READTEIQVV | LVENGPETGG | AGRLARALLA | DVAENGEALG | VLEATMRESG | 
    400:
    AHVWGSSAAG | LAGGVAAAVL | LALLVLLVAP | PLLRRAGRLR | WRRHEAAAPA | 
    450:
    GAPLGFRNPV | FDVTASEELP | LPRRLSLVPK | AAADSTSHSY | FVNPLFAGAE | 
    453:
    AEA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    KEGG:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein amnionless
    ELISA Kit for Human Protein amnionless
    ELISA Kit for Human Protein amnionless
    CLIA Kit for Human Protein amnionless
    CLIA Kit for Human Protein amnionless
    CLIA Kit for Human Protein amnionless
    Polyclonal Antibody for Human Protein amnionless
    Polyclonal Antibody for Human Protein amnionless
    Polyclonal Antibody for Human Protein amnionless
    Monoclonal Antibody for Human Protein amnionless
    Monoclonal Antibody for Human Protein amnionless
    Monoclonal Antibody for Human Protein amnionless
    Protein for Human Protein amnionless
    Protein for Human Protein amnionless
    Protein for Human Protein amnionless

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain."
      Kalantry S. , Manning S. , Haub O. , Tomihara-Newberger C. , Lee H.-G. , Fangman J. , Disteche C.M. , Manova K. , Lacy E.
      Nat. Genet.27:412-416(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-230
    4. 4.
      "Amnionless, essential for mouse gastrulation, is mutated in recessive hereditary megaloblastic anemia."
      Tanner S.M. , Aminoff M. , Wright F.A. , Liyanarachchi S. , Kuronen M. , Saarinen A. , Massika O. , Mandel H. , Broch H. , de la Chapelle A.
      Nat. Genet.33:426-429(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 300-323 AND 393-453;TISSUE SPECIFICITY;VARIANT RH-MGA1 ILE-41
    5. 5.
      "The functional cobalamin (vitamin B12)-intrinsic factor receptor is a novel complex of cubilin and amnionless."
      Fyfe J.C. , Madsen M. , Hoejrup P. , Christensen E.I. , Tanner S.M. , de la Chapelle A. , He Q. , Moestrup S.K.
      Blood103:1573-1579(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY;INTERACTION WITH CUBN;TISSUE SPECIFICITY
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RH-MGA1
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