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Index > Protein center > Amph(Gene name) > Rat
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  • Amph (Gene name),
  • Amphiphysin (Protein name ),  AMPH_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Amph(Amph1);
    Protein name:
    Amphiphysin;
    Alternative:

    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Heterodimer with BIN1. Binds SH3GLB1 (By similarity). Binds AP2A2. Interacts with AP2B1.
    Function:
    May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton.
    Subcellular Location:
    Cytoplasmic vesicle secretory vesicle synaptic vesicle membrane Peripheral membrane protein Cytoplasmic side Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    683
    Sequence:
    50:
    MADIKTGIFA | KNVQKRLNRA | QEKVLQKLGK | ADETKDEQFE | EYVQNFKRQE | 
    100:
    AEGTRLQREL | RGYLAAIKGM | QEASMKLTES | LHEVYEPDWY | GREDVKMVGE | 
    150:
    KCDVLWEDFH | QKLVDGSLLT | LDTYLGQFPD | IKNRIAKRSR | KLVDYDSARH | 
    200:
    HLEALQSSKR | KDESRISKAE | EEFQKAQKVF | EEFNVDLQEE | LPSLWSRRVG | 
    250:
    FYVNTFKNVS | SLEAKFHKEI | AVLCHKLYEV | MTKLGDQHAD | KAFSIQGAPS | 
    300:
    DSGPLRIAKT | PSPPEEASPL | PSPTASPNHT | LAPASPAPVR | PRSPSQTRKG | 
    350:
    PPVPPLPKVT | PTKELQQENI | INFFEDNFVP | EINVTTPSQN | EVLEVKKEET | 
    400:
    LLDLDFDPFK | PDVTPAGSAA | ATHSPMSQTL | PWDLWTTSTD | LVQPASGGSF | 
    450:
    NDFTQPQDTS | LFTMQTDQNM | AETEQALPTE | PQAEEPPTTA | AAPTAGLDLG | 
    500:
    LEMEEPKEEA | AIPPGTDAGE | TVGTEGSTGE | EAEAEKAALP | AGEGESPEGA | 
    550:
    KIDVESTELA | SSESPQAAEL | EAGAPQEKVI | PSVVIEPASN | HEGEEHQETT | 
    600:
    TGTETREATE | DVAPQGPAGE | KQELATEPTP | LDSQAATPAP | AGAVDASLSA | 
    650:
    GDAAQELPPG | FLYKVETLHD | FEAANSDELT | LQRGDVVLVV | PSDSEADQDA | 
    683:
    GWLVGVKESD | WLQYRDLATY | KGLFPENFTR | HLE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    Pfam:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Amphiphysin
    ELISA Kit for Rat Amphiphysin
    ELISA Kit for Rat Amphiphysin
    ELISA Kit for Rat Amphiphysin
    CLIA Kit for Rat Amphiphysin
    CLIA Kit for Rat Amphiphysin
    CLIA Kit for Rat Amphiphysin
    CLIA Kit for Rat Amphiphysin
    Polyclonal Antibody for Rat Amphiphysin
    Polyclonal Antibody for Rat Amphiphysin
    Polyclonal Antibody for Rat Amphiphysin
    Polyclonal Antibody for Rat Amphiphysin
    Monoclonal Antibody for Rat Amphiphysin
    Monoclonal Antibody for Rat Amphiphysin
    Monoclonal Antibody for Rat Amphiphysin
    Monoclonal Antibody for Rat Amphiphysin
    Protein for Rat Amphiphysin
    Protein for Rat Amphiphysin
    Protein for Rat Amphiphysin
    Protein for Rat Amphiphysin

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Amphiphysin heterodimers: potential role in clathrin-mediated endocytosis."
      Wigge P. , Koehler K. , Vallis Y. , Doyle C. , Owen D. , Hunt S.P. , McMahon H.T.
      Mol. Biol. Cell8:2003-2015(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: Sprague-Dawley.
      tissue: Brain cortex.
    2. 2.
      Lubec G. , Chen W.-Q.
      Submitted (2007-04) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 198-207; 242-256 AND 615-633;IDENTIFICATION BY MASS SPECTROMETRY
      strain: Sprague-Dawley.
      tissue: Hippocampus.
    3. 3.
      "A structural explanation for the binding of multiple ligands by the alpha-adaptin appendage domain."
      Owen D.J. , Vallis Y. , Noble M.E.M. , Hunter J.B. , Dafforn T.R. , Evans P.R. , McMahon H.T.
      Cell97:805-815(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AP2A2
    4. 4.
      "Crystal structure of the alpha appendage of AP-2 reveals a recruitment platform for clathrin-coat assembly."
      Traub L.M. , Downs M.A. , Westrich J.L. , Fremont D.H.
      Proc. Natl. Acad. Sci. U.S.A.96:8907-8912(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AP2A2
    5. 5.
      "Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly."
      Edeling M.A. , Mishra S.K. , Keyel P.A. , Steinhauser A.L. , Collins B.M. , Roth R. , Heuser J.E. , Owen D.J. , Traub L.M.
      Dev. Cell10:329-342(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AP2B1
    6. 6.
      "Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly."
      Schmid E.M. , Ford M.G.J. , Burtey A. , Praefcke G.J.K. , Peak-Chew S.-Y. , Mills I.G. , Benmerah A. , McMahon H.T.
      PLoS Biol.4:E262-E262(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH AP2B1
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