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Index > Protein center > ANPEP(Gene name) > Dog
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  • ANPEP (Gene name),
  • Aminopeptidase N (Protein name ),  AMPN_CANFA from NCBI database.
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  • General Annotation
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  • Gene name:
    ANPEP;
    Protein name:
    Aminopeptidase N(AP-N;cAPN);
    Alternative:
    Aminopeptidase M(AP-M);Alanyl aminopeptidase;Microsomal aminopeptidase;
    CD:
    CD13;
    Organism:
    Dog (Canis familiarisCanis lupus familiaris). 
    General Annotation
    Sub Unit:
    Homodimer (By similarity). Interacts with CCoV spike glycoprotein.
    Function:
    Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May be involved in the metabolism of regulatory peptides of diverse cell types and in the cleavage of peptides bound to major histocompatibility complex class II molecules of antigen presenting cells. May have a role in angiogenesis (By similarity). In case of canine coronavirus (CCoV), serves as a receptor for CCoV spike glycoprotein in a species-specific manner.
    Subcellular Location:
    Membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    191
    Sequence:
    50:
    DLSVIPVINR | AQVIHDTFDL | ASAQIVPVTL | ALNSTLFLNQ | ETEYMPWEAA | 
    100:
    LSSLSYFKLM | FDRSEVYGPM | KNYLRKQVTP | LFNHFEKITQ | NWTDHPQTLT | 
    150:
    EQYNEINAVS | TACTYGVPKC | KDLVSTLFAE | WRKNPQNNPI | YPNLRSTVYC | 
    191:
    NAIAQGGEEE | WNFVWEQFRN | TSLVNEADKL | RSALACSTQV | W
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Dog AP-N
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    ELISA Kit for Dog AP-N
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    ELISA Kit for Dog AP-N
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    ELISA Kit for Dog AP-N
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    ELISA Kit for Dog AP-N
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    ELISA Kit for Dog AP-N
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    E9154d
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    ELISA Kit for Dog AP-N
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    E9154b
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    CLIA Kit for Dog AP-N
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    U9154p
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    CLIA Kit for Dog AP-N
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    U9154h
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    CLIA Kit for Dog AP-N
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    U9154m
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    CLIA Kit for Dog AP-N
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    CLIA Kit for Dog AP-N
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    U9154d
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    96T
    CLIA Kit for Dog AP-N
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    U9154r
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    CLIA Kit for Dog AP-N
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    U9154b
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    CLIA Kit for Dog AP-N
    Cat.:
    U9154c
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Dog AP-N
    Polyclonal Antibody for Dog AP-N
    Polyclonal Antibody for Dog AP-N
    Polyclonal Antibody for Dog AP-N
    Cat.:
    P9154Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog AP-N
    Polyclonal Antibody for Dog AP-N
    Polyclonal Antibody for Dog AP-N
    Cat.:
    P9154Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Dog AP-N
    Cat.:
    P9154Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Monoclonal Antibody for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N
    Protein for Dog AP-N

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    References
    1. 1.
      "Interspecies aminopeptidase-N chimeras reveal species-specific receptor recognition by canine coronavirus, feline infectious peritonitis virus, and transmissible gastroenteritis virus."
      Benbacer L. , Kut E. , Besnardeau L. , Laude H. , Delmas B.
      J. Virol.71:734-737(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH CCOV SPIKE GLYCOPROTEIN;IDENTIFICATION OF RECEPTOR FUNCTIONAL DOMAINS FOR CCOV INFECTION
      tissue: Small intestine.
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