Anp32a ELISA Kit for Mouse(Mus musculus) | EIAab.comAnp32a ELISA Kit for Mouse(Mus musculus)

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Anp32a (Gene name),

Acidic leucine-rich nuclear phosphoprotein 32 family member A (Protein name ), AN32A_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Anp32a(Anp32;Lanp);

Protein name:

Acidic leucine-rich nuclear phosphoprotein 32 family member A;

Alternative:

Leucine-rich acidic nuclear protein(LANP);Acidic nuclear phosphoprotein pp32;Potent heat-stable protein phosphatase 2A inhibitor I1PP2A;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Component of the SET complex, which also contains SET, APEX1, HMGB2 and NME1. Directly interacts with SET. Interacts with ATXN1/SCA1. Interacts with MAP1B. Interacts with ELAVL1. Part of the INHAT (inhibitor of histone acetyltransferases) complex (By similarity). Interacts with E4F1.

Function:

Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase-independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1-mediated transcriptional repression.

Subcellular Location:

Nucleus Cytoplasm Endoplasmic reticulum Shuttles between nucleus and cytoplasm. Translocates to the cytoplasm during the process of neuritogenesis.

Protein Attributes:

Sequence length:

247

Sequence:

50:

100:

150:

200:

247:

VSGEEEEDEE | GYNDGEVDDE | EDEEEAGEEE | GSQKRKREPD | DEGEEDD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.269088

KEGG:

mmu:11737

SMR:

O35381

String:

O35381

Uniprot:

O35381

FOR

ELISA Kit for Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member A

CLIA Kit for Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member A

Polyclonal Antibody for Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member A

Monoclonal Antibody for Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member A

Protein for Mouse Acidic leucine-rich nuclear phosphoprotein 32 family member A

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure of pp32, an acidic nuclear protein which inhibits oncogene-induced formation of transformed foci."
Chen T.-H. , Brody J.R. , Romantsev F.E. , Yu J.-G. , Kayler A.E. , Voneiff E. , Kuhajda F.P. , Pasternack G.R.
Mol. Biol. Cell7:2045-2056(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"The cerebellar leucine-rich acidic nuclear protein interacts with ataxin-1."
Matilla A. , Koshy B.T. , Cummings C.J. , Isobe T. , Orr H.T. , Zoghbi H.Y.
Nature389:974-978(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];INTERACTION WITH SCA1
tissue: Cerebellum.
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6.
tissue: Brain.
4.

"Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis."
Opal P. , Garcia J.J. , Propst F. , Matilla A. , Orr H.T. , Zoghbi H.Y.
J. Biol. Chem.278:34691-34699(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION;INTERACTION WITH MAP1B
5.

"Generation and characterization of LANP/pp32 null mice."
Opal P. , Garcia J.J. , McCall A.E. , Xu B. , Weeber E.J. , Sweatt J.D. , Orr H.T. , Zoghbi H.Y.
Mol. Cell. Biol.24:3140-3149(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DISRUPTION PHENOTYPE
6.

"The Anp32 family of proteins containing leucine-rich repeats."
Matilla A. , Radrizzani M.
Cerebellum4:7-18(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GENE FAMILY;NOMENCLATURE;TISSUE SPECIFICITY
7.

"The role of LANP and ataxin 1 in E4F-mediated transcriptional repression."
Cvetanovic M. , Rooney R.J. , Garcia J.J. , Toporovskaya N. , Zoghbi H.Y. , Opal P.
EMBO Rep.8:671-677(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH E4F1
8.

"Evolutionary divergence of enzymatic mechanisms for posttranslational polyglycylation."
Rogowski K. , Juge F. , van Dijk J. , Wloga D. , Strub J.-M. , Levilliers N. , Thomas D. , Bre M.-H. , Van Dorsselaer A. , Gaertig J. , Janke C.
Cell137:1076-1087(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCYLATION

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