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Index > Protein center > Anapc2(Gene name) > Mouse
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  • Anapc2 (Gene name),
  • Anaphase-promoting complex subunit 2 (Protein name ),  ANC2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Anapc2;
    Protein name:
    Anaphase-promoting complex subunit 2(APC2);
    Alternative:
    Cyclosome subunit 2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    The APC/C is composed of at least 12 subunits (By similarity). Interacts with NEUROD2.
    Function:
    Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 drives presynaptic differentiation.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    837
    Sequence:
    50:
    MEAEGVAVAA | AAAAAAAAAT | IIASDDCDSR | PGQELLVAWN | TVSTGLVPPA | 
    100:
    ALGLASSRTS | GAVPPKEEEL | RAAVEVLRGH | GLHSVLEEWF | VEVLQNDLQG | 
    150:
    NIATEFWNAI | ALRENSVDEP | QCLGLLLDAF | GLLESRLDPY | LHSLELLEKW | 
    200:
    TRLGLLMGAG | AQGLREKVHT | MLRGVLFFST | PRTFQEMVQR | LYGRFLRVYM | 
    250:
    QSKRKGEGGT | DPELEGELDS | RYARRRYYRL | LQSPLCAGCG | SDKQQCWCRQ | 
    300:
    ALEQFNQLSQ | VLHRLSLLER | VCAEAVTTTL | HQVTRERMED | RCRGEYERSF | 
    350:
    LREFHKWIER | VVGWLGKVFL | QDNPTRPTSP | EAGNTLRRWR | CHVQRFFYRI | 
    400:
    YATLRIEELF | SIIRDFPDSR | PAIEDLKYCL | ERTDQRQQLL | VSLKVALETR | 
    450:
    LLHPGVNTCD | IITLYISAIK | ALRVLDPSMV | ILEVACEPIR | RYLRTREDTV | 
    500:
    RQIVAGLTGD | SDGTGDLAVE | LSKTDPACLE | TGQDSEDDSG | EPEDWVPDPV | 
    550:
    DADPVKSSSK | RRSSDIISLL | VSIYGSKDLF | INEYRSLLAD | RLLHQFSFSP | 
    600:
    EREIRNVELL | KLRFGEAPMH | FCEVMLKDMA | DSRRINANIR | EEDEKRPVEE | 
    650:
    QPPFGVYAVI | LSSEFWPPFK | DEKLEVPEDI | RAALDVYCKK | YEKLKAMRTL | 
    700:
    SWKHTLGLVT | MDVELADRTL | SVAVTPVQAV | VLLYFQNQAS | WTLEELSKVV | 
    750:
    KMPVALLRRR | MSVWLQQGVL | REEPPGTFSV | IEEERPQDRD | NMVLIDSDDE | 
    800:
    SDSGMASQAD | QKEEELLLFW | AYIQAMLTNL | ESLSLERIYS | MLRMFVMTGP | 
    837:
    ALAEIDLQEL | QGYLQKKVRD | QQLIYSAGVY | RLPKNSN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse APC2
    ELISA Kit for Mouse APC2
    CLIA Kit for Mouse APC2
    CLIA Kit for Mouse APC2
    Polyclonal Antibody for Mouse APC2
    Polyclonal Antibody for Mouse APC2
    Monoclonal Antibody for Mouse APC2
    Monoclonal Antibody for Mouse APC2
    Protein for Mouse APC2
    Protein for Mouse APC2

    R&D Technical Data
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      strain: NOD.
      tissue: Epididymis.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Quantitative time-resolved phosphoproteomic analysis of mast cell signaling."
      Cao L. , Yu K. , Banh C. , Nguyen V. , Ritz A. , Raphael B.J. , Kawakami Y. , Kawakami T. , Salomon A.R.
      J. Immunol.179:5864-5876(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-825;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Mast cell.
    5. 5.
      "A Cdc20-APC ubiquitin signaling pathway regulates presynaptic differentiation."
      Yang Y. , Kim A.H. , Yamada T. , Wu B. , Bilimoria P.M. , Ikeuchi Y. , de la Iglesia N. , Shen J. , Bonni A.
      Science326:575-578(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH NEUROD2
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