AGT ELISA Kit for Human(Homo sapiens) | EIAab.comAGT ELISA Kit for Human(Homo sapiens)

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AGT (Gene name),

Angiotensinogen (Protein name ), ANGT_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Citations (2)

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Gene name:

AGT(SERPINA8);

Protein name:

Angiotensinogen;

Alternative:

Serpin A8;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

During pregnancy, exists as a disulfide-linked 2:2 heterotetramer with the proform of PRG2 and as a complex (probably a 2:2:2 heterohexamer) with pro-PRG2 and C3dg.

Function:

Angiotensin 1-7 is a ligand for the G-protein coupled receptor MAS1 (By similarity). Has vasodilator and antidiuretic effects (By similarity). Has an antithrombotic effect that involves MAS1-mediated release of nitric oxide from platelets.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

485

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

485:

VLEVTLNRPF | LFAVYDQSAT | ALHFLGRVAN | PLSTA

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

STRING:

9606.ENSP00000355627

String:

P01019

KEGG:

hsa:183

MIM:

106150

Pfam:

PF00079

UniGene:

Hs.19383

SMR:

P01019

Uniprot:

P01019

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ELISA Kit for Human Angiotensinogen

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E0797h

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96T

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ELISA Kit for Human Angiotensinogen

Cat.:

E0797m

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96T

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ELISA Kit for Human Angiotensinogen

Cat.:

E0797r

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ELISA Kit for Human Angiotensinogen

MSDS:

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ELISA Kit for Human Angiotensinogen

MSDS:

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CLIA Kit for Human Angiotensinogen

MSDS:

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CLIA Kit for Human Angiotensinogen

MSDS:

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CLIA Kit for Human Angiotensinogen

Cat.:

U0797r

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96T

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CLIA Kit for Human Angiotensinogen

Cat.:

U0797m

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

Please sign in first.

CLIA Kit for Human Angiotensinogen

Cat.:

U0797h

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96T

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Polyclonal Antibody for Human Angiotensinogen

Cat.:

P0797Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Angiotensinogen

Cat.:

P0797Rb-m

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40ug/0.2ml

Polyclonal Antibody for Human Angiotensinogen

Cat.:

P0797Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Angiotensinogen

Monoclonal Antibody for Human Angiotensinogen

Protein for Human Angiotensinogen

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Citations

[1].

"Plasma kallikrein-bradykinin pathway promotes circulatory nitric oxide metabolite availability during hypoxia"

Padhy G, Gangwar A, Sharma M, et al.

From:Nitric Oxide

[2].

"Plasma Proteomics of Ladakhi Natives Reveal Functional Regulation Between Renin–Angiotensin System and eNOS–cGMP Pathway"

Padhy G, Gangwar A, Sharma M, et al.

From:High Altitude Medicine & Biology

References

1.

"Primary structure of human preangiotensinogen deduced from the cloned cDNA sequence."
Kageyama R. , Ohkubo H. , Nakanishi S.
Biochemistry23:3603-3609(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Structure of human angiotensinogen gene."
Gaillard I. , Clauser E. , Corvol P.
DNA8:87-99(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
3.

"Structure and expression of the human angiotensinogen gene. Identification of a unique and highly active promoter."
Fukamizu A. , Takahashi S. , Seo M.S. , Tada M. , Tanimoto K. , Uehara S. , Murakami K.
J. Biol. Chem.265:7576-7582(1990) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
4.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT SER-335
tissue: Brain.
5.

"Molecular cloning of human angiotensinogen cDNA and evidence for the presence of its mRNA in rat heart."
Kunapuli S.P. , Kumar A.
Circ. Res.60:786-790(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-338
6.

"Tissue specific hormonal regulation of the rat angiotensinogen gene expression."
Kunapuli S.P. , Benedict C.R. , Kumar A.
Arch. Biochem. Biophys.254:642-646(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 32-184
7.

"The amino terminal amino acid sequence of human angiotensinogen."
Tewksbury D.A. , Dart R.A. , Travis J.
Biochem. Biophys. Res. Commun.99:1311-1315(1981) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 34-58
8.

"Identification of angiotensinogen and complement C3dg as novel proteins binding the proform of eosinophil major basic protein in human pregnancy serum and plasma."
Oxvig C. , Haaning J. , Kristensen L. , Wagner J.M. , Rubin I. , Stigbrand T. , Gleich G.J. , Sottrup-Jensen L.
J. Biol. Chem.270:13645-13651(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 34-45;SUBUNIT
tissue: Serum.
9.

"Enzymatic degradation and electrophoresis of human angiotensin I."
Arakawa K. , Minohara A. , Yamada J. , Nakamura M.
Biochim. Biophys. Acta168:106-112(1968) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 34-43
10.

"Processing of rat and human angiotensinogen precursors by microsomal membranes."
Campbell D.J. , Bouhnik J. , Coezy E. , Menard J. , Corvol P.
Mol. Cell. Endocrinol.43:31-40(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-47; ASN-170; ASN-304 AND ASN-328
11.

"Angiotensin III: (DES-Aspartic Acid-1)-Angiotensin II. Evidence and speculation for its role as an important agonist in the renin -angiotensin system."
Goodfriend T.L. , Peach M.J.
Circ. Res.36:38-48(1975) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ANGIOTENSIN-3
12.

"The renin-angiotensin-aldosterone system: a specific target for hypertension management."
Weir M.R. , Dzau V.J.
Am. J. Hypertens.12:205S-213S(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION OF ANGIOTENSIN-2
13.

"A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1-9."
Donoghue M. , Hsieh F. , Baronas E. , Godbout K. , Gosselin M. , Stagliano N. , Donovan M. , Woolf B. , Robison K. , Jeyaseelan R. , Breitbart R.E. , Acton S.
Circ. Res.87:E1-E9(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE BY ACE AND ACE2
14.

"Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase."
Vickers C. , Hales P. , Kaushik V. , Dick L. , Gavin J. , Tang J. , Godbout K. , Parsons T. , Baronas E. , Hsieh F. , Acton S. , Patane M.A. , Nichols A. , Tummino P.
J. Biol. Chem.277:14838-14843(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CLEAVAGE OF ANGIOTENSIN-1 AND ANGIOTENSIN-2 BY ACE2
15.

"Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism."
Rice G.I. , Thomas D.A. , Grant P.J. , Turner A.J. , Hooper N.M.
Biochem. J.383:45-51(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ANGIOTENSIN PEPTIDES METABOLISM
16.

"Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-47
tissue: Plasma.
17.

"Mass-spectrometric identification of a novel angiotensin peptide in human plasma."
Jankowski V. , Vanholder R. , van der Giet M. , Tolle M. , Karadogan S. , Gobom J. , Furkert J. , Oksche A. , Krause E. , Tran T.N. , Tepel M. , Schuchardt M. , Schluter H. , Wiedon A. , Beyermann M. , Bader M. , Todiras M. , Zidek W. , more...
Arterioscler. Thromb. Vasc. Biol.27:297-302(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DECARBOXYLATION AT ASP-34;FUNCTION;IDENTIFICATION BY MASS SPECTROMETRY
18.

"Renin-angiotensin system revisited."
Fyhrquist F. , Saijonmaa O.
J. Intern. Med.264:224-236(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON THE RENIN-ANGIOTENSIN SYSTEM
19.

"Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-47
tissue: Liver.
20.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"The octapeptide angiotensin II adopts a well-defined structure in a phospholipid environment."
Carpenter K.A. , Wilkes B.C. , Schiller P.W.
Eur. J. Biochem.251:448-453(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF ANGIOTENSIN-2
22.

"Comparison of the solution structures of angiotensin I & II. Implication for structure-function relationship."
Spyroulias G.A. , Nikolakopoulou P. , Tzakos A. , Gerothanassis I.P. , Magafa V. , Manessi-Zoupa E. , Cordopatis P.
Eur. J. Biochem.270:2163-2173(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 34-43;STRUCTURE BY NMR OF 34-41
23.

"A redox switch in angiotensinogen modulates angiotensin release."
Zhou A. , Carrell R.W. , Murphy M.P. , Wei Z. , Yan Y. , Stanley P.L. , Stein P.E. , Broughton Pipkin F. , Read R.J.
Nature468:108-111(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (4.33 ANGSTROMS) OF 34-485 IN COMPLEX WITH RENIN;DISULFIDE BOND
24.

"Molecular basis of human hypertension: role of angiotensinogen."
Jeunemaitre X. , Soubrier F. , Kotelevtsev Y.V. , Lifton R.P. , Williams C.S. , Charru A. , Hunt S.C. , Hopkins P.N. , Williams R.R. , Lalouel J.-M. , Corvol P.
Cell71:169-180(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS MET-207; THR-268 AND CYS-281
25.

"A molecular variant of angiotensinogen associated with preeclampsia."
Ward K. , Hata A. , Jeunemaitre X. , Helin C. , Nelson L. , Namikawa C. , Farrington P.F. , Ogasawara M. , Suzumori K. , Tomoda S. , Berrebi S. , Sasaki M. , Corvol P. , Lifton R.P. , Lalouel J.-M.
Nat. Genet.4:59-61(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT THR-268
26.

"Detection and characterization of new mutations in the human angiotensinogen gene (AGT)."
Hixson J.E. , Powers P.K.
Hum. Genet.96:110-112(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS ILE-242; ARG-244 AND CYS-281
27.

"A mutation of angiotensinogen in a patient with preeclampsia leads to altered kinetics of the renin-angiotensin system."
Inoue I. , Rohrwasser A. , Helin C. , Jeunemaitre X. , Crain P. , Bohlender J. , Lifton R.P. , Corvol P. , Ward K. , Lalouel J.-M.
J. Biol. Chem.270:11430-11436(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PHE-43
28.

"The natural mutation Y248C of human angiotensinogen leads to abnormal glycosylation and altered immunological recognition of the protein."
Gimenez-Roqueplo A.P. , Leconte I. , Cohen P. , Simon D. , Guyene T.T. , Celerier J. , Pau B. , Corvol P. , Clauser E. , Jeunemaitre X.
J. Biol. Chem.271:9838-9844(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANT CYS-281
29.

"Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis."
Gribouval O. , Gonzales M. , Neuhaus T. , Aziza J. , Bieth E. , Laurent N. , Bouton J.M. , Feuillet F. , Makni S. , Ben Amar H. , Laube G. , Delezoide A.-L. , Bouvier R. , Dijoud F. , Ollagnon-Roman E. , Roume J. , Joubert M. , Antignac C. , more...
Nat. Genet.37:964-968(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT RTD GLN-375

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