Ank3 ELISA Kit for Mouse(Mus musculus) | EIAab.comAnk3 ELISA Kit for Mouse(Mus musculus)

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Ank3 (Gene name),

Ankyrin-3 (Protein name ), ANK3_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Ank3;

Protein name:

Ankyrin-3(ANK-3);

Alternative:

Ankyrin-G;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

May be a constituent of a neurofascin/NRCAM/ankyrin G complex. Interacts with RHBG (By similarity). Directly interacts with DMD and betaDAG1; this interaction does not interfere with DMD-binding and is required for DMD and betaDAG1 retention at costameres. Interacts (via N-terminal ANK repeats) with SCHIP1 isoform 7 (via C-terminus); this interaction is required for the localization at axon initial segments (AISs) and nodes of Ranvier (NRs).

Function:

Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments (By similarity). In skeletal muscle, required for costamere localization of DMD and betaDAG1.

Subcellular Location:

Cytoplasm Cytoskeleton Cell membrane Sarcolemma Cell junction Synapse Postsynaptic cell membrane Lysosome In skeletal muscle, localized at costameres and neuromuscular junctions. In bone marrow-derived macrophages, isoforms 2 and 3 are associated with lysosomes.

Protein Attributes:

Sequence length:

1961

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1961:

KEIRNVEKKT | H

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Mm.235960

SMR:

G5E8K5

KEGG:

mmu:11735

Pfam:

PF12796

Uniprot:

G5E8K5

FOR

ELISA Kit for Mouse ANK-3

CLIA Kit for Mouse ANK-3

Polyclonal Antibody for Mouse ANK-3

Monoclonal Antibody for Mouse ANK-3

Protein for Mouse ANK-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain."
Peters L.L. , John K.M. , Lu F.M. , Eicher E.M. , Higgins A. , Yialamas M. , Turtzo L.C. , Otsuka A.J. , Lux S.E.
J. Cell Biol.130:313-330(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 4 AND 6);TISSUE SPECIFICITY
strain: C57BL/6J.
tissue: Kidney.
2.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-1726 (ISOFORMS 4/5/6)
strain: C57BL/6J.
tissue: Urinary bladder.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: FVB/N.
tissue: Salivary gland.
6.

"Isoforms of ankyrin-3 that lack the NH2-terminal repeats associate with mouse macrophage lysosomes."
Hoock T.C. , Peters L.L. , Lux S.E.
J. Cell Biol.136:1059-1070(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 742-1961 (ISOFORMS 2 AND 3);SUBCELLULAR LOCATION;TISSUE SPECIFICITY
strain: C3H/HeJ.
tissue: Bone marrow macrophage.
7.

"An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan."
Ayalon G. , Davis J.Q. , Scotland P.B. , Bennett V.
Cell135:1189-1200(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH DMD;SUBCELLULAR LOCATION
8.

"Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments."
Martin P.M. , Carnaud M. , Garcia del Cano G. , Irondelle M. , Irinopoulou T. , Girault J.A. , Dargent B. , Goutebroze L.
J. Neurosci.28:6111-6117(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SCHIP1
9.

"Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C."
Maiweilidan Y. , Klauza I. , Kordeli E.
Exp. Cell Res.317:724-736(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE

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