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Index > Protein center > PRMT3(Gene name) > Human
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  • PRMT3 (Gene name),
  • Protein arginine N-methyltransferase 3 (Protein name ),  ANM3_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PRMT3(HRMT1L3);
    Protein name:
    Protein arginine N-methyltransferase 3;
    Alternative:
    Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    May exist as a monomer or homodimer.
    Function:
    Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    531
    Sequence:
    50:
    MCSLASGATG | GRGAVENEED | LPELSDSGDE | AAWEDEDDAD | LPHGKQQTPC | 
    100:
    LFCNRLFTSA | EETFSHCKSE | HQFNIDSMVH | KHGLEFYGYI | KLINFIRLKN | 
    150:
    PTVEYMNSIY | NPVPWEKEEY | LKPVLEDDLL | LQFDVEDLYE | PVSVPFSYPN | 
    200:
    GLSENTSVVE | KLKHMEARAL | SAEAALARAR | EDLQKMKQFA | QDFVMHTDVR | 
    250:
    TCSSSTSVIA | DLQEDEDGVY | FSSYGHYGIH | EEMLKDKIRT | ESYRDFIYQN | 
    300:
    PHIFKDKVVL | DVGCGTGILS | MFAAKAGAKK | VLGVDQSEIL | YQAMDIIRLN | 
    350:
    KLEDTITLIK | GKIEEVHLPV | EKVDVIISEW | MGYFLLFESM | LDSVLYAKNK | 
    400:
    YLAKGGSVYP | DICTISLVAV | SDVNKHADRI | AFWDDVYGFK | MSCMKKAVIP | 
    450:
    EAVVEVLDPK | TLISEPCGIK | HIDCHTTSIS | DLEFSSDFTL | KITRTSMCTA | 
    500:
    IAGYFDIYFE | KNCHNRVVFS | TGPQSTKTHW | KQTVFLLEKP | FSVKAGEALK | 
    531:
    GKVTVHKSKK | DPRSLTVTLT | LNNSTQTYGL | Q
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    Pfam:
    UniGene:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Protein arginine N-methyltransferase 3
    ELISA Kit for Human Protein arginine N-methyltransferase 3
    ELISA Kit for Human Protein arginine N-methyltransferase 3
    CLIA Kit for Human Protein arginine N-methyltransferase 3
    CLIA Kit for Human Protein arginine N-methyltransferase 3
    CLIA Kit for Human Protein arginine N-methyltransferase 3
    Polyclonal Antibody for Human Protein arginine N-methyltransferase 3
    Polyclonal Antibody for Human Protein arginine N-methyltransferase 3
    Polyclonal Antibody for Human Protein arginine N-methyltransferase 3
    Monoclonal Antibody for Human Protein arginine N-methyltransferase 3
    Monoclonal Antibody for Human Protein arginine N-methyltransferase 3
    Monoclonal Antibody for Human Protein arginine N-methyltransferase 3
    Protein for Human Protein arginine N-methyltransferase 3
    Protein for Human Protein arginine N-methyltransferase 3
    Protein for Human Protein arginine N-methyltransferase 3

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ASN-508
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANT ASN-508
      tissue: Brain.
    4. 4.
      "PRMT 3, a type I protein arginine N-methyltransferase that differs from PRMT1 in its oligomerization, subcellular localization, substrate specificity, and regulation."
      Tang J. , Gary J.D. , Clarke S. , Herschman H.R.
      J. Biol. Chem.273:16935-16945(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 20-531 (ISOFORM 1);VARIANT ASN-508
    5. 5.
      "DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo."
      Singh V. , Miranda T.B. , Jiang W. , Frankel A. , Roemer M.E. , Robb V.A. , Gutmann D.H. , Herschman H.R. , Clarke S. , Newsham I.F.
      Oncogene23:7761-7771(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH EPB41L3
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S. , Helbig A.O. , Slijper M. , Krijgsveld J. , Heck A.J. , Mohammed S.
      Anal. Chem.81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT CYS-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
    8. 8.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25 AND SER-27;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    9. 9.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25 AND SER-27;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    11. 11.
      "Tyrosine 87 is vital for the activity of human protein arginine methyltransferase 3 (PRMT3)."
      Handrkova H. , Petrak J. , Halada P. , Pospisilova D. , Cmejla R.
      Biochim. Biophys. Acta1814:277-282(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT SER-25 AND SER-27;MUTAGENESIS OF TYR-87;ABSENCE OF PHOSPHORYLATION AT TYR-87;INTERACTION WITH RPS2
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-25 AND SER-27;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
      Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
      Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT CYS-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT CYS-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    15. 15.
      "The crystal structure of human HMT1 HNRNP methyltransferase-like 3 in complex with SAH."
      Structural genomics consortium (SGC)
      Submitted (2006-03) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 211-531 IN COMPLEX WITH S-ADENOSYL-L-HOMOCYSTEINE
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