Gene name:
PRMT7 (RCJMB04_28e13) ;
Protein name:
Protein arginine N-methyltransferase 7 ;
Alternative:
2.1.1.126;[Myelin basic protein]-arginine N-methyltransferase PRMT7 ) ;2.1.1.125;Histone-arginine N-methyltransferase PRMT7 ) ;
Organism:
Chicken (Gallus gallus).
General Annotation
Function:
Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being recruited by CTCFL at the H19 imprinted control region (ICR) and methylating histone H4 to form H4R3me2s, possibly leading to recruit DNA methyltransferases at these sites. May also play a role in embryonic stem cell (ESC) pluripotency. Also able to mediate the arginine methylation of histone H2A and myelin basic protein (MBP) in vitro; the relevance of such results is however unclear in vivo.
Subcellular Location:
Cytoplasm
cytosol
Nucleus
Protein Attributes:
50:
MKTFCGRANP | TTGSLEWVEE | DEDYDYHQEI | ARSRYADMLH | DKDRNMKYYQ |
100:
GIRAAVSRVK | GRGEKAIVLD | IGTGTGLLSM | MAASAGADFC | YAVEVFKPMA |
150:
NAAVKIVEKN | GFGDKIKVIN | KHSTEVTVGP | DGDMQCRANI | LVTELFDTEL |
200:
IGEGALPTYE | HAHKYLVQEG | CEAVPHRATV | YVQLVESKRM | WSWNKLFPVH |
250:
VEAEDGEKII | VSPSEMENCP | GVPSVCDIQL | NQMPSSDFTI | LSDVVTMFSV |
300:
DFSKPVRSAS | TCYRAQLDPV | KSGKAQIVLS | WWDIDMDPSG | TINCTMAPYW |
350:
VKPMSAFQWR | DHWMQCVYFL | PKEEQVLQGE | KVHLTACRDE | YSVWYTLQKA |
400:
REEDESKADA | RVESPVCRCQ | AHLLWNRPRF | GELNDQNRTR | QYIKSLMSVL |
450:
RTDSVCLCIS | DGSLLPVLAH | YLGAEQVFTL | ENSAVSCSVM | KKFFKANHLE |
500:
DKIKIVEARP | ELLTSSHLEE | KKISVLVGEP | FFTTSLLPWH | NLYFWYARTA |
550:
VTEHLASDVT | VLPQSAALHM | MIVEFQDLWR | IRSPCGTCEG | FDVQTMDDMI |
600:
KNSLNFRESK | EAEPHPLWEY | PCKSLSNPQE | VLLFDFRKTV | PQHCLSTEGS |
650:
VNLLRKGKSH | GAVLWMEYHL | TADISVSTGL | MQISNEKGNC | EWNPHCKQAV |
689:
YFFSSVIESE | TLADVPTAVT | YAIKFDTKTG | EIAMDFKLL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Chicken
Human
Bovine
Rat
ELISA Kit for Chicken Protein arginine N-methyltransferase 7
ELISA Kit for Chicken Protein arginine N-methyltransferase 7
ELISA Kit for Chicken Protein arginine N-methyltransferase 7
ELISA Kit for Chicken Protein arginine N-methyltransferase 7
ELISA Kit for Chicken Protein arginine N-methyltransferase 7
CLIA Kit for Chicken Protein arginine N-methyltransferase 7
CLIA Kit for Chicken Protein arginine N-methyltransferase 7
CLIA Kit for Chicken Protein arginine N-methyltransferase 7
CLIA Kit for Chicken Protein arginine N-methyltransferase 7
CLIA Kit for Chicken Protein arginine N-methyltransferase 7
Polyclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Polyclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Polyclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Polyclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Polyclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Monoclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Monoclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Monoclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Monoclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Monoclonal Antibody for Chicken Protein arginine N-methyltransferase 7
Protein for Chicken Protein arginine N-methyltransferase 7
Protein for Chicken Protein arginine N-methyltransferase 7
Protein for Chicken Protein arginine N-methyltransferase 7
Protein for Chicken Protein arginine N-methyltransferase 7
Protein for Chicken Protein arginine N-methyltransferase 7
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis."
Caldwell R.B.
,
Kierzek A.M.
,
Arakawa H.
,
Bezzubov Y.
,
Zaim J.
,
Fiedler P.
,
Kutter S.
,
Blagodatski A.
,
Kostovska D.
,
Koter M.
,
Plachy J.
,
Carninci P.
,
Hayashizaki Y.
,
Buerstedde J.-M.
Genome Biol.6:R6.1-R6.9(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
CB .
tissue :
Bursa of Fabricius .