Gene name:
ANO1 (DOG1;ORAOV2;TAOS2;TMEM16A) ;
Protein name:
Anoctamin-1 ;
Alternative:
Oral cancer overexpressed protein 2 ;Discovered on gastrointestinal stromal tumors protein 1 ;Tumor-amplified and overexpressed sequence 2 ;Transmembrane protein 16A ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
Acts as a calcium-activated chloride channel. Required for normal tracheal development.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Cytoplasm
Protein Attributes:
50:
MRVNEKYSTL | PAEDRSVHII | NICAIEDIGY | LPSEGTLLNS | LSVDPDAECK |
100:
YGLYFRDGRR | KVDYILVYHH | KRPSGNRTLV | RRVQHSDTPS | GARSVKQDHP |
150:
LPGKGASLDA | GSGEPPMDYH | EDDKRFRREE | YEGNLLEAGL | ELERDEDTKI |
200:
HGVGFVKIHA | PWNVLCREAE | FLKLKMPTKK | MYHINETRGL | LKKINSVLQK |
250:
ITDPIQPKVA | EHRPQTMKRL | SYPFSREKQH | LFDLSDKDSF | FDSKTRSTIV |
300:
YEILKRTTCT | KAKYSMGITS | LLANGVYAAA | YPLHDGDYNG | ENVEFNDRKL |
350:
LYEEWARYGV | FYKYQPIDLV | RKYFGEKIGL | YFAWLGVYTQ | MLIPASIVGI |
400:
IVFLYGCATM | DENIPSMEMC | DQRHNITMCP | LCDKTCSYWK | MSSACATARA |
450:
SHLFDNPATV | FFSVFMALWA | ATFMEHWKRK | QMRLNYRWDL | TGFEEEEEAV |
500:
KDHPRAEYEA | RVLEKSLKKE | SRNKEKRRHI | PEESTNKWKQ | RVKTAMAGVK |
550:
LTDKVKLTWR | DRFPAYLTNL | VSIIFMIAVT | FAIVLGVIIY | RISMAAALAM |
600:
NSSPSVRSNI | RVTVTATAVI | INLVVIILLD | EVYGCIARWL | TKIEVPKTEK |
650:
SFEERLIFKA | FLLKFVNSYT | PIFYVAFFKG | RFVGRPGDYV | YIFRSFRMEE |
700:
CAPGGCLMEL | CIQLSIIMLG | KQLIQNNLFE | IGIPKMKKLI | RYLKLKQQSP |
750:
PDHEECVKRK | QRYEVDYNLE | PFAGLTPEYM | EMIIQFGFVT | LFVASFPLAP |
800:
LFALLNNIIE | IRLDAKKFVT | ELRRPVAVRA | KDIGIWYNIL | RGIGKLAVII |
850:
NAFVISFTSD | FIPRLVYLYM | YSKNGTMHGF | VNHTLSSFNV | SDFQNGTAPN |
900:
DPLDLGYEVQ | ICRYKDYREP | PWSENKYDIS | KDFWAVLAAR | LAFVIVFQNL |
950:
VMFMSDFVDW | VIPDIPKDIS | QQIHKEKVLM | VELFMREEQD | KQQLLETWME |
986:
KERQKDEPPC | NHHNTKACPD | SLGSPAPSHA | YHGGVL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Anoctamin-1
ELISA Kit for Human Anoctamin-1
CLIA Kit for Human Anoctamin-1
CLIA Kit for Human Anoctamin-1
Polyclonal Antibody for Human Anoctamin-1
Polyclonal Antibody for Human Anoctamin-1
Monoclonal Antibody for Human Anoctamin-1
Monoclonal Antibody for Human Anoctamin-1
Protein for Human Anoctamin-1
Protein for Human Anoctamin-1
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY
2.
"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T.
,
Suzuki Y.
,
Nishikawa T.
,
Otsuki T.
,
Sugiyama T.
,
Irie R.
,
Wakamatsu A.
,
Hayashi K.
,
Sato H.
,
Nagai K.
,
Kimura K.
,
Makita H.
,
Sekine M.
,
Obayashi M.
,
Nishi T.
,
Shibahara T.
,
Tanaka T.
,
Ishii S.
,
Yamamoto J.
,
Saito K.
,
Kawai Y.
,
Isono Y.
,
Nakamura Y.
,
Nagahari K.
,
Murakami K.
,
Yasuda T.
,
Iwayanagi T.
,
Wagatsuma M.
,
Shiratori A.
,
Sudo H.
,
Hosoiri T.
,
Kaku Y.
,
Kodaira H.
,
Kondo H.
,
Sugawara M.
,
Takahashi M.
,
Kanda K.
,
Yokoi T.
,
Furuya T.
,
Kikkawa E.
,
Omura Y.
,
Abe K.
,
Kamihara K.
,
Katsuta N.
,
Sato K.
,
Tanikawa M.
,
Yamazaki M.
,
Ninomiya K.
,
Ishibashi T.
,
Yamashita H.
,
Murakawa K.
,
Fujimori K.
,
Tanai H.
,
Kimata M.
,
Watanabe M.
,
Hiraoka S.
,
Chiba Y.
,
Ishida S.
,
Ono Y.
,
Takiguchi S.
,
Watanabe S.
,
Yosida M.
,
Hotuta T.
,
Kusano J.
,
Kanehori K.
,
Takahashi-Fujii A.
,
Hara H.
,
Tanase T.-O.
,
Nomura Y.
,
Togiya S.
,
Komai F.
,
Hara R.
,
Takeuchi K.
,
Arita M.
,
Imose N.
,
Musashino K.
,
Yuuki H.
,
Oshima A.
,
Sasaki N.
,
Aotsuka S.
,
Yoshikawa Y.
,
Matsunawa H.
,
Ichihara T.
,
Shiohata N.
,
Sano S.
,
Moriya S.
,
Momiyama H.
,
Satoh N.
,
Takami S.
,
Terashima Y.
,
Suzuki O.
,
Nakagawa S.
,
Senoh A.
,
Mizoguchi H.
,
Goto Y.
,
Shimizu F.
,
Wakebe H.
,
Hishigaki H.
,
Watanabe T.
,
Sugiyama A.
,
Takemoto M.
,
Kawakami B.
,
Yamazaki M.
,
Watanabe K.
,
Kumagai A.
,
Itakura S.
,
Fukuzumi Y.
,
Fujimori Y.
,
Komiyama M.
,
Tashiro H.
,
Tanigami A.
,
Fujiwara T.
,
Ono T.
,
Yamada K.
,
Fujii Y.
,
Ozaki K.
,
Hirao M.
,
Ohmori Y.
,
Kawabata A.
,
Hikiji T.
,
Kobatake N.
,
Inagaki H.
,
Ikema Y.
,
Okamoto S.
,
Okitani R.
,
Kawakami T.
,
Noguchi S.
,
Itoh T.
,
Shigeta K.
,
Senba T.
,
Matsumura K.
,
Nakajima Y.
,
Mizuno T.
,
Morinaga M.
,
Sasaki M.
,
Togashi T.
,
Oyama M.
,
Hata H.
,
Watanabe M.
,
Komatsu T.
,
Mizushima-Sugano J.
,
Satoh T.
,
Shirai Y.
,
Takahashi Y.
,
Nakagawa K.
,
Okumura K.
,
Nagase T.
,
Nomura N.
,
Kikuchi H.
,
Masuho Y.
,
Yamashita R.
,
Nakai K.
,
Yada T.
,
Nakamura Y.
,
Ohara O.
,
Isogai T.
,
Sugano S.
more...
Nat. Genet.36:40-45(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
tissue :
Testis .
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
tissue :
Testis .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION;TOPOLOGY
5.
"The novel marker, DOG1, is expressed ubiquitously in gastrointestinal stromal tumors irrespective of KIT or PDGFRA mutation status."
West R.B.
,
Corless C.L.
,
Chen X.
,
Rubin B.P.
,
Subramanian S.
,
Montgomery K.
,
Zhu S.
,
Ball C.A.
,
Nielsen T.O.
,
Patel R.
,
Goldblum J.R.
,
Brown P.O.
,
Heinrich M.C.
,
van de Rijn M.
Am. J. Pathol.165:107-113(2004)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION;TISSUE SPECIFICITY
6.
"Head and neck squamous cell carcinoma transcriptome analysis by comprehensive validated differential display."
Carles A.
,
Millon R.
,
Cromer A.
,
Ganguli G.
,
Lemaire F.
,
Young J.
,
Wasylyk C.
,
Muller D.
,
Schultz I.
,
Rabouel Y.
,
Dembele D.
,
Zhao C.
,
Marchal P.
,
Ducray C.
,
Bracco L.
,
Abecassis J.
,
Poch O.
,
Wasylyk B.
Oncogene25:1821-1831(2006)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH CFTR;ENZYME REGULATION
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBUNIT
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
14.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
15.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW;FUNCTION;SUBCELLULAR LOCATION
16.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
17.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION