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Index > Protein center > ANO7(Gene name) > Human
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  • ANO7 (Gene name),
  • Anoctamin-7 (Protein name ),  ANO7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ANO7(NGEP;PCANAP5;TMEM16G);
    Protein name:
    Anoctamin-7;
    Alternative:
    IPCA-5;Dresden transmembrane protein of the prostate(D-TMPP);Prostate cancer-associated protein 5;New gene expressed in prostate;Transmembrane protein 16G;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May act as a calcium-activated chloride channel. May play a role in cell-cell interactions.
    Subcellular Location:
    Isoform 2 Cytoplasm cytosol
    Protein Attributes:
    Sequence length:
    933
    Sequence:
    50:
    MRMAATAWAG | LQGPPLPTLC | PAVRTGLYCR | DQAHAERWAM | TSETSSGSHC | 
    100:
    ARSRMLRRRA | QEEDSTVLID | VSPPEAEKRG | SYGSTAHASE | PGGQQAAACR | 
    150:
    AGSPAKPRIA | DFVLVWEEDL | KLDRQQDSAA | RDRTDMHRTW | RETFLDNLRA | 
    200:
    AGLCVDQQDV | QDGNTTVHYA | LLSASWAVLC | YYAEDLRLKL | PLQELPNQAS | 
    250:
    NWSAGLLAWL | GIPNVLLEVV | PDVPPEYYSC | RFRVNKLPRF | LGSDNQDTFF | 
    300:
    TSTKRHQILF | EILAKTPYGH | EKKNLLGIHQ | LLAEGVLSAA | FPLHDGPFKT | 
    350:
    PPEGPQAPRL | NQRQVLFQHW | ARWGKWNKYQ | PLDHVRRYFG | EKVALYFAWL | 
    400:
    GFYTGWLLPA | AVVGTLVFLV | GCFLVFSDIP | TQELCGSKDS | FEMCPLCLDC | 
    450:
    PFWLLSSACA | LAQAGRLFDH | GGTVFFSLFM | ALWAVLLLEY | WKRKSATLAY | 
    500:
    RWDCSDYEDT | EERPRPQFAA | SAPMTAPNPI | TGEDEPYFPE | RSRARRMLAG | 
    550:
    SVVIVVMVAV | VVMCLVSIIL | YRAIMAIVVS | RSGNTLLAAW | ASRIASLTGS | 
    600:
    VVNLVFILIL | SKIYVSLAHV | LTRWEMHRTQ | TKFEDAFTLK | VFIFQFVNFY | 
    650:
    SSPVYIAFFK | GRFVGYPGNY | HTLFGVRNEE | CAAGGCLIEL | AQELLVIMVG | 
    700:
    KQVINNMQEV | LIPKLKGWWQ | KFRLRSKKRK | AGASAGASQG | PWEDDYELVP | 
    750:
    CEGLFDEYLE | MVLQFGFVTI | FVAACPLAPL | FALLNNWVEI | RLDARKFVCE | 
    800:
    YRRPVAERAQ | DIGIWFHILA | GLTHLAVISN | AFLLAFSSDF | LPRAYYRWTR | 
    850:
    AHDLRGFLNF | TLARAPSSFA | AAHNRTCRYR | AFRDDDGHYS | QTYWNLLAIR | 
    900:
    LAFVIVFEHV | VFSVGRLLDL | LVPDIPESVE | IKVKREYYLA | KQALAENEVL | 
    933:
    FGTNGTKDEQ | PEGSELSSHW | TPFTVPKASQ | LQQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    MIM:
    Pfam:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human Anoctamin-7
    ELISA Kit for Human Anoctamin-7
    ELISA Kit for Human Anoctamin-7
    CLIA Kit for Human Anoctamin-7
    CLIA Kit for Human Anoctamin-7
    CLIA Kit for Human Anoctamin-7
    Polyclonal Antibody for Human Anoctamin-7
    Polyclonal Antibody for Human Anoctamin-7
    Polyclonal Antibody for Human Anoctamin-7
    Monoclonal Antibody for Human Anoctamin-7
    Monoclonal Antibody for Human Anoctamin-7
    Monoclonal Antibody for Human Anoctamin-7
    Protein for Human Anoctamin-7
    Protein for Human Anoctamin-7
    Protein for Human Anoctamin-7

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "NGEP, a gene encoding a membrane protein detected only in prostate cancer and normal prostate."
      Bera T.K. , Das S. , Maeda H. , Beers R. , Wolfgang C.D. , Kumar V. , Hahn Y. , Lee B. , Pastan I.
      Proc. Natl. Acad. Sci. U.S.A.101:3059-3064(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2);VARIANT LYS-912;TISSUE SPECIFICITY;SUBCELLULAR LOCATION;TOPOLOGY
    2. 2.
      "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W. , Graves T.A. , Fulton R.S. , Fulton L.A. , Pepin K.H. , Minx P. , Wagner-McPherson C. , Layman D. , Wylie K. , Sekhon M. , Becker M.C. , Fewell G.A. , Delehaunty K.D. , Miner T.L. , Nash W.E. , Kremitzki C. , Oddy L. , Du H. , more...
      Nature434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "Prediction of gene function by genome-scale expression analysis: prostate cancer-associated genes."
      Walker M.G. , Volkmuth W. , Sprinzak E. , Hodgson D. , Klingler T.
      Genome Res.9:1198-1203(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    4. 4.
      "Characterization of human TMEM16G gene in silico."
      Katoh M. , Katoh M.
      Int. J. Mol. Med.14:759-764(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION
    5. 5.
      "D-TMPP: a novel androgen-regulated gene preferentially expressed in prostate and prostate cancer that is the first characterized member of an eukaryotic gene family."
      Kiessling A. , Weigle B. , Fuessel S. , Ebner R. , Meye A. , Rieger M.A. , Schmitz M. , Temme A. , Bachmann M. , Wirth M.P. , Rieber E.P.
      Prostate64:387-400(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ALTERNATIVE SPLICING (ISOFORM 3);TISSUE SPECIFICITY;INDUCTION BY ANDROGEN
    6. 6.
      "NGEP, a prostate-specific plasma membrane protein that promotes the association of LNCaP cells."
      Das S. , Hahn Y. , Nagata S. , Willingham M.C. , Bera T.K. , Lee B. , Pastan I.
      Cancer Res.67:1594-1601(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    7. 7.
      "Topology of NGEP, a prostate-specific cell:cell junction protein widely expressed in many cancers of different grade level."
      Das S. , Hahn Y. , Walker D.A. , Nagata S. , Willingham M.C. , Peehl D.M. , Bera T.K. , Lee B. , Pastan I.
      Cancer Res.68:6306-6312(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION AT ASN-809 AND ASN-824;MEMBRANE TOPOLOGY
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    9. 9.
      "Physiological roles and diseases of Tmem16/Anoctamin proteins: are they all chloride channels?"
      Duran C. , Hartzell H.C.
      Acta Pharmacol. Sin.32:685-692(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    11. 11.
      "ANOs 3-7 in the anoctamin/Tmem16 Cl- channel family are intracellular proteins."
      Duran C. , Qu Z. , Osunkoya A.O. , Cui Y. , Hartzell H.C.
      Am. J. Physiol.302:C482-C493(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ABSENCE OF CALCIUM-ACTIVATED CHLORIDE CHANNEL ACTIVITY;SUBCELLULAR LOCATION
    12. 12.
      "The anoctamin (TMEM16) gene family: calcium-activated chloride channels come of age."
      Winpenny J.P. , Gray M.A.
      Exp. Physiol.97:175-176(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    13. 13.
      "The anoctamin family: TMEM16A and TMEM16B as calcium-activated chloride channels."
      Scudieri P. , Sondo E. , Ferrera L. , Galietta L.J.
      Exp. Physiol.97:177-183(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW;ABSENCE OF CALCIUM-ACTIVATED CHLORIDE CHANNEL ACTIVITY
    14. 14.
      "Anoctamins are a family of Ca2+ activated Cl- channels."
      Tian Y. , Schreiber R. , Kunzelmann K.
      J. Cell Sci.125:4991-4998(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
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