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Index > Protein center > ANKRD11(Gene name) > Human
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  • ANKRD11 (Gene name),
  • Ankyrin repeat domain-containing protein 11 (Protein name ),  ANR11_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ANKRD11(ANCO1);
    Protein name:
    Ankyrin repeat domain-containing protein 11;
    Alternative:
    Ankyrin repeat-containing cofactor 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the PAS region of the p160 coactivators.
    Function:
    May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    2663
    Sequence:
    50:
    MPKGGCPKAP | QQEELPLSSD | MVEKQTGKKD | KDKVSLTKTP | KLERGDGGKE | 
    100:
    VRERASKRKL | PFTAGANGEQ | KDSDTEKQGP | ERKRIKKEPV | TRKAGLLFGM | 
    150:
    GLSGIRAGYP | LSERQQVALL | MQMTAEESAN | SPVDTTPKHP | SQSTVCQKGT | 
    200:
    PNSASKTKDK | VNKRNERGET | RLHRAAIRGD | ARRIKELISE | GADVNVKDFA | 
    250:
    GWTALHEACN | RGYYDVAKQL | LAAGAEVNTK | GLDDDTPLHD | AANNGHYKVV | 
    300:
    KLLLRYGGNP | QQSNRKGETP | LKVANSPTMV | NLLLGKGTYT | SSEESSTESS | 
    350:
    EEEDAPSFAP | SSSVDGNNTD | SEFEKGLKHK | AKNPEPQKAT | APVKDEYEFD | 
    400:
    EDDEQDRVPP | VDDKHLLKKD | YRKETKSNSF | ISIPKMEVKS | YTKNNTIAPK | 
    450:
    KASHRILSDT | SDEEDASVTV | GTGEKLRLSA | HTILPGSKTR | EPSNAKQQKE | 
    500:
    KNKVKKKRKK | ETKGREVRFG | KRSDKFCSSE | SESESSESGE | DDRDSLGSSG | 
    550:
    CLKGSPLVLK | DPSLFSSLSA | SSTSSHGSSA | AQKQNPSHTD | QHTKHWRTDN | 
    600:
    WKTISSPAWS | EVSSLSDSTR | TRLTSESDYS | SEGSSVESLK | PVRKRQEHRK | 
    650:
    RASLSEKKSP | FLSSAEGAVP | KLDKEGKVVK | KHKTKHKHKN | KEKGQCSISQ | 
    700:
    ELKLKSFTYE | YEDSKQKSDK | AILLENDLST | ENKLKVLKHD | RDHFKKEEKL | 
    750:
    SKMKLEEKEW | LFKDEKSLKR | IKDTNKDISR | SFREEKDRSN | KAEKERSLKE | 
    800:
    KSPKEEKLRL | YKEERKKKSK | DRPSKLEKKN | DLKEDKISKE | KEKIFKEDKE | 
    850:
    KLKKEKVYRE | DSAFDEYCNK | NQFLENEDTK | FSLSDDQRDR | WFSDLSDSSF | 
    900:
    DFKGEDSWDS | PVTDYRDMKS | DSVAKLILET | VKEDSKERRR | DSRAREKRDY | 
    950:
    REPFFRKKDR | DYLDKNSEKR | KEQTEKHKSV | PGYLSEKDKK | RRESAEAGRD | 
    1000:
    RKDALESCKE | RRDGRAKPEE | AHREELKECG | CESGFKDKSD | GDFGKGLEPW | 
    1050:
    ERHHPAREKE | KKDGPDKERK | EKTKPERYKE | KSSDKDKSEK | SILEKCQKDK | 
    1100:
    EFDKCFKEKK | DTKEKHKDTH | GKDKERKASL | DQGKEKKEKA | FPGIISEDFS | 
    1150:
    EKKDDKKGKE | KSWYIADIFT | DESEDDRDSC | MGSGFKMGEA | SDLPRTDGLQ | 
    1200:
    EKEEGREAYA | SDRHRKSSDK | QHPERQKDKE | PRDRRKDRGA | ADAGRDKKEK | 
    1250:
    VFEKHKEKKD | KESTEKYKDR | KDRASVDSTQ | DKKNKQKLPE | KAEKKHAAED | 
    1300:
    KAKSKHKEKS | DKEHSKERKS | SRSADAEKSL | LEKLEEEALH | EYREDSNDKI | 
    1350:
    SEVSSDSFTD | RGQEPGLTAF | LEVSFTEPPG | DDKPRESACL | PEKLKEKERH | 
    1400:
    RHSSSSSKKS | HDRERAKKEK | AEKKEKGEDY | KEGGSRKDSG | QYEKDFLEAD | 
    1450:
    AYGVSYNMKA | DIEDELDKTI | ELFSTEKKDK | NDSEREPSKK | IEKELKPYGS | 
    1500:
    SAINILKEKK | KREKHREKWR | DEKERHRDRH | ADGLLRHHRD | ELLRHHRDEQ | 
    1550:
    KPATRDKDSP | PRVLKDKSRD | EGPRLGDAKL | KEKFKDGAEK | EKGDPVKMSN | 
    1600:
    GNDKVAPSKD | PGKKDARPRE | KLLGDGDLMM | TSFERMLSQK | DLEIEERHKR | 
    1650:
    HKERMKQMEK | LRHRSGDPKL | KEKAKPADDG | RKKGLDIPAK | KPPGLDPPFK | 
    1700:
    DKKLKESTPI | PPAAENKLHP | ASGADSKDWL | AGPHMKEVLP | ASPRPDQSRP | 
    1750:
    TGVPTPTSVL | SCPSYEEVMH | TPRTPSCSAD | DYADLVFDCA | DSQHSTPVPT | 
    1800:
    APTSACSPSF | FDRFSVASSG | LSENASQAPA | RPLSTNLYRS | VSVDIRRTPE | 
    1850:
    EEFSVGDKLF | RQQSVPAASS | YDSPMPPSME | DRAPLPPVPA | EKFACLSPGY | 
    1900:
    YSPDYGLPSP | KVDALHCPPA | AVVTVTPSPE | GVFSSLQAKP | SPSPRAELLV | 
    1950:
    PSLEGALPPD | LDTSEDQQAT | AAIIPPEPSY | LEPLDEGPFS | AVITEEPVEW | 
    2000:
    AHPSEQALAS | SLIGGTSENP | VSWPVGSDLL | LKSPQRFPES | PKRFCPADPL | 
    2050:
    HSAAPGPFSA | SEAPYPAPPA | SPAPYALPVA | EPGLEDVKDG | VDAVPAAIST | 
    2100:
    SEAAPYAPPS | GLESFFSNCK | SLPEAPLDVA | PEPACVAAVA | QVEALGPLEN | 
    2150:
    SFLDGSRGLS | HLGQVEPVPW | ADAFAGPEDD | LDLGPFSLPE | LPLQTKDAAD | 
    2200:
    GEAEPVEESL | APPEEMPPGA | PGVINGGDVS | TVVAEEPPAL | PPDQASTRLP | 
    2250:
    AELEPEPSGE | PKLDVALEAA | VEAETVPEER | ARGDPDSSVE | PAPVPPEQRP | 
    2300:
    LGSGDQGAEA | EGPPAASLCA | PDGPAPNTVA | QAQAADGAGP | EDDTEASRAA | 
    2350:
    APAEGPPGGI | QPEAAEPKPT | AEAPKAPRVE | EIPQRMTRNR | AQMLANQSKQ | 
    2400:
    GPPPSEKECA | PTPAPVTRAK | ARGSEDDDAQ | AQHPRKRRFQ | RSTQQLQQQL | 
    2450:
    NTSTQQTREV | IQQTLAAIVD | AIKLDAIEPY | HSDRANPYFE | YLQIRKKIEE | 
    2500:
    KRKILCCITP | QAPQCYAEYV | TYTGSYLLDG | KPLSKLHIPV | IAPPPSLAEP | 
    2550:
    LKELFRQQEA | VRGKLRLQHS | IEREKLIVSC | EQEILRVHCR | AARTIANQAV | 
    2600:
    PFSACTMLLD | SEVYNMPLES | QGDENKSVRD | RFNARQFISW | LQDVDDKYDR | 
    2650:
    MKTCLLMRQQ | HEAAALNAVQ | RMEWQLKVQE | LDPAGHKSLC | VNEVPSFYVP | 
    2663:
    MVDVNDDFVL | LPA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    MIM:
    SMR:
    String:
    Pfam:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ankyrin repeat domain-containing protein 11
    CLIA Kit for Human Ankyrin repeat domain-containing protein 11
    Polyclonal Antibody for Human Ankyrin repeat domain-containing protein 11
    Monoclonal Antibody for Human Ankyrin repeat domain-containing protein 11
    Protein for Human Ankyrin repeat domain-containing protein 11

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "ANKRD11 and ANKRD12 are novel 9kb genes encoding nuclear-located proteins with ankyrin domains."
      Powell J.A. , Settasatian C. , Lower K. , Callen D.F.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
    2. 2.
      "Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators."
      Zhang A. , Yeung P.L. , Li C.-W. , Tsai S.-C. , Dinh G.K. , Wu X. , Li H. , Chen J.D.
      J. Biol. Chem.279:33799-33805(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;INTERACTION WITH P160
    3. 3.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-451
      tissue: Pancreas.
    5. 5.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1509;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-408; THR-410; SER-411; SER-834; THR-1120; SER-1123; THR-1419; SER-1792; SER-1847 AND SER-1859;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    7. 7.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-408; THR-410 AND SER-411;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    8. 8.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-276; SER-408; THR-410; SER-411; SER-834 AND THR-1419;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Mutations in ANKRD11 cause KBG syndrome, characterized by intellectual disability, skeletal malformations, and macrodontia."
      Sirmaci A. , Spiliopoulos M. , Brancati F. , Powell E. , Duman D. , Abrams A. , Bademci G. , Agolini E. , Guo S. , Konuk B. , Kavaz A. , Blanton S. , Digilio M.C. , Dallapiccola B. , Young J. , Zuchner S. , Tekin M.
      Am. J. Hum. Genet.89:289-294(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN KBGS
    10. 10.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-408; THR-410; SER-411 AND SER-834;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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