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Index > Protein center > ANKRD12(Gene name) > Human
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  • ANKRD12 (Gene name),
  • Ankyrin repeat domain-containing protein 12 (Protein name ),  ANR12_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    ANKRD12(ANCO2;KIAA0874);
    Protein name:
    Ankyrin repeat domain-containing protein 12;
    Alternative:
    GAC-1 protein;Ankyrin repeat-containing cofactor 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with the PAS region of the p160 coactivators.
    Function:
    May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    2062
    Sequence:
    50:
    MPKSGFTKPI | QSENSDSDSN | MVEKPYGRKS | KDKIASYSKT | PKIERSDVSK | 
    100:
    EMKEKSSMKR | KLPFTISPSR | NEERDSDTDS | DPGHTSENWG | ERLISSYRTY | 
    150:
    SEKEGPEKKK | TKKEAGNKKS | TPVSILFGYP | LSERKQMALL | MQMTARDNSP | 
    200:
    DSTPNHPSQT | TPAQKKTPSS | SSRQKDKVNK | RNERGETPLH | MAAIRGDVKQ | 
    250:
    VKELISLGAN | VNVKDFAGWT | PLHEACNVGY | YDVAKILIAA | GADVNTQGLD | 
    300:
    DDTPLHDSAS | SGHRDIVKLL | LRHGGNPFQA | NKHGERPVDV | AETEELELLL | 
    350:
    KREVPLSDDD | ESYTDSEEAQ | SVNPSSVDEN | IDSETEKDSL | ICESKQILPS | 
    400:
    KTPLPSALDE | YEFKDDDDEE | INKMIDDRHI | LRKEQRKENE | PEAEKTHLFA | 
    450:
    KQEKAFYPKS | FKSKKQKPSR | VLYSSTESSD | EEALQNKKIS | TSCSVIPETS | 
    500:
    NSDMQTKKEY | VVSGEHKQKG | KVKRKLKNQN | KNKENQELKQ | EKEGKENTRI | 
    550:
    TNLTVNTGLD | CSEKTREEGN | FRKSFSPKDD | TSLHLFHIST | GKSPKHSCGL | 
    600:
    SEKQSTPLKQ | EHTKTCLSPG | SSEMSLQPDL | VRYDNTESEF | LPESSSVKSC | 
    650:
    KHKEKSKHQK | DFHLEFGEKS | NAKIKDEDHS | PTFENSDCTL | KKMDKEGKTL | 
    700:
    KKHKLKHKER | EKEKHKKEIE | GEKEKYKTKD | SAKELQRSVE | FDREFWKENF | 
    750:
    FKSDETEDLF | LNMEHESLTL | EKKSKLEKNI | KDDKSTKEKH | VSKERNFKEE | 
    800:
    RDKIKKESEK | SFREEKIKDL | KEERENIPTD | KDSEFTSLGM | SAIEESIGLH | 
    850:
    LVEKEIDIEK | QEKHIKESKE | KPEKRSQIKE | KDIEKMERKT | FEKEKKIKHE | 
    900:
    HKSEKDKLDL | SECVDKIKEK | DKLYSHHTEK | CHKEGEKSKN | TAAIKKTDDR | 
    950:
    EKSREKMDRK | HDKEKPEKER | HLAESKEKHL | MEKKNKQSDN | SEYSKSEKGK | 
    1000:
    NKEKDRELDK | KEKSRDKESI | NITNSKHIQE | EKKSSIVDGN | KAQHEKPLSL | 
    1050:
    KEKTKDEPLK | TPDGKEKDKK | DKDIDRYKER | DKHKDKIQIN | SLLKLKSEAD | 
    1100:
    KPKPKSSPAS | KDTRPKEKRL | VNDDLMQTSF | ERMLSLKDLE | IEQWHKKHKE | 
    1150:
    KIKQKEKERL | RNRNCLELKI | KDKEKTKHTP | TESKNKELTR | SKSSEVTDAY | 
    1200:
    TKEKQPKDAV | SNRSQSVDTK | NVMTLGKSSF | VSDNSLNRSP | RSENEKPGLS | 
    1250:
    SRSVSMISVA | SSEDSCHTTV | TTPRPPVEYD | SDFMLESSES | QMSFSQSPFL | 
    1300:
    SIAKSPALHE | RELDSLADLP | ERIKPPYANR | LSTSHLRSSS | VEDVKLIISE | 
    1350:
    GRPTIEVRRC | SMPSVICEHT | KQFQTISEES | NQGSLLTVPG | DTSPSPKPEV | 
    1400:
    FSNVPERDLS | NVSNIHSSFA | TSPTGASNSK | YVSADRNLIK | NTAPVNTVMD | 
    1450:
    SPVHLEPSSQ | VGVIQNKSWE | MPVDRLETLS | TRDFICPNSN | IPDQESSLQS | 
    1500:
    FCNSENKVLK | ENADFLSLRQ | TELPGNSCAQ | DPASFMPPQQ | PCSFPSQSLS | 
    1550:
    DAESISKHMS | LSYVANQEPG | ILQQKNAVQI | ISSALDTDNE | STKDTENTFV | 
    1600:
    LGDVQKTDAF | VPVYSDSTIQ | EASPNFEKAY | TLPVLPSEKD | FNGSDASTQL | 
    1650:
    NTHYAFSKLT | YKSSSGHEVE | NSTTDTQVIS | HEKENKLESL | VLTHLSRCDS | 
    1700:
    DLCEMNAGMP | KGNLNEQDPK | HCPESEKCLL | SIEDEESQQS | ILSSLENHSQ | 
    1750:
    QSTQPEMHKY | GQLVKVELEE | NAEDDKTENQ | IPQRMTRNKA | NTMANQSKQI | 
    1800:
    LASCTLLSEK | DSESSSPRGR | IRLTEDDDPQ | IHHPRKRKVS | RVPQPVQVSP | 
    1850:
    SLLQAKEKTQ | QSLAAIVDSL | KLDEIQPYSS | ERANPYFEYL | HIRKKIEEKR | 
    1900:
    KLLCSVIPQA | PQYYDEYVTF | NGSYLLDGNP | LSKICIPTIT | PPPSLSDPLK | 
    1950:
    ELFRQQEVVR | MKLRLQHSIE | REKLIVSNEQ | EVLRVHYRAA | RTLANQTLPF | 
    2000:
    SACTVLLDAE | VYNVPLDSQS | DDSKTSVRDR | FNARQFMSWL | QDVDDKFDKL | 
    2050:
    KTCLLMRQQH | EAAALNAVQR | LEWQLKLQEL | DPATYKSISI | YEIQEFYVPL | 
    2062:
    VDVNDDFELT | PI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    SMR:
    MIM:
    Pfam:
    String:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ankyrin repeat domain-containing protein 12
    CLIA Kit for Human Ankyrin repeat domain-containing protein 12
    Polyclonal Antibody for Human Ankyrin repeat domain-containing protein 12
    Monoclonal Antibody for Human Ankyrin repeat domain-containing protein 12
    Protein for Human Ankyrin repeat domain-containing protein 12

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Recovery
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "GAC-1 protein containing ankyrin repeats."
      Ilyin G.P.
      Submitted (2000-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "ANKRD11 and ANKRD12 are novel 9kb genes encoding nuclear-located proteins with ankyrin domains."
      Powell J.A. , Settasatian C. , Lower K. , Callen D.F.
      Submitted (2003-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);VARIANT THR-171;SUBCELLULAR LOCATION
    3. 3.
      "Identification of a novel family of ankyrin repeats-containing cofactors for p160 nuclear receptor coactivators."
      Zhang A. , Yeung P.L. , Li C.-W. , Tsai S.-C. , Dinh G.K. , Wu X. , Li H. , Chen J.D.
      J. Biol. Chem.279:33799-33805(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);SUBCELLULAR LOCATION;INTERACTION WITH P160
    4. 4.
      Chen J.D.
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT ARG-906
      tissue: Testis.
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-484;VARIANT THR-171
    7. 7.
      "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Suyama M. , Kikuno R. , Hirosawa M. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:355-364(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1462-2062
      tissue: Brain.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-861;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Platelet.
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-149;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
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