Protein name:
Ankyrin repeat and sterile alpha motif domain-containing protein 1B ;
Alternative:
E2A-PBX1-associated protein (EB-1) ;Amyloid-beta protein intracellular domain-associated protein 1 (AIDA-1) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Isoform 3 interacts with DLG4 (By similarity). Interacts with EPHA8. Isoform 2 interacts with COIL. Isoform 4 interacts with APP and EPHA8. Isoform 6 interacts with EPHA8.
Function:
Isoform 4 may play a role as a modulator of APP processing. Overexpression can down-regulate APP processing.
Subcellular Location:
Isoform 6
Nucleus
Protein Attributes:
50:
MGKDQELLEA | ARTGNVALVE | KLLSGRKGGI | LGGGSGPLPL | SNLLSIWRGP |
100:
NVNCTDSSGY | TALHHAALNG | HKDIVLKLLQ | YEASTNVADN | KGYFPIHLAA |
150:
WKGDVEIVKI | LIHHGPSHSR | VNEQNNENET | ALHCAAQYGH | SEVVAVLLEE |
200:
LTDPTIRNSK | LETPLDLAAL | YGRLRVVKMI | ISAHPNLMSC | NTRKHTPLHL |
250:
AARNGHKAVV | QVLLEAGMDV | SCQTEKGSAL | HEAALFGKVD | VVRVLLETGI |
300:
DANIKDSLGR | TVLDILKEHP | SQKSLQIATL | LQEYLEGVGR | STVLEEPVQE |
350:
DATQETHISS | PVESPSQKTK | SETVTGELSK | LLDEIKLCQE | KDYSFEDLCH |
400:
TISDHYLDNL | SKISEEELGK | NGSQSVRTSS | TINLSPGEVE | EEDDDENTCG |
450:
PSGLWEALTP | CNGCRNLGFP | MLAQESYPKK | RNYTMEIVPS | ASLDTFPSEN |
500:
ENFLCDLMDT | AVTKKPCSLE | IARAPSPRTD | NASEVAVTTP | GTSNHRNSST |
550:
GPTPDCSPPS | PDTALKNIVK | VIRPQPKQRT | SIVSSLDFHR | MNHNQEYFEI |
600:
NTSTGCTSFT | ASPPASPPTS | SVGTTEVKNE | GTNHTDDLSR | QDDNDPPKEY |
650:
DPGQFAGLLH | GSSPACESPE | NPFHLYGKRE | QCEKGQDEVS | LANSPLPFKQ |
700:
SPIENNSEPL | VKKIKPKVVS | RTIFHKKSNQ | LENHTIVGTR | STRSGSRNGD |
750:
QWVMNAGGFV | ERACTLGRIR | SLPKALIDMH | LSKSVSKSDS | DLIAYPSNEK |
800:
TSRVNWSESS | TAEHSSKGNS | ERTPSFTSEW | EEIDKIMSSI | DVGINNELKE |
850:
MNGETTRPRC | PVQTVGQWLE | SIGLPQYENH | LMANGFDNVQ | FMGSNVMEDQ |
900:
DLLEIGILNS | GHRQRILQAI | QLLPKMRPIG | HDGYHPTSVA | EWLDSIELGD |
950:
YTKAFLINGY | TSMDLLKKIW | EVELINVLKI | NLIGHRKRIL | ASLGDRLHDD |
1000:
PPQKPPRSIT | LREPSGNHTP | PQLSPSLSQS | TYTTGGSLDV | PHIIMQGDAR |
1050:
RRRNENYFDD | IPRSKLERQM | AQTGDWGEPS | ITLRPPNEAT | ASTPVQYWQH |
1100:
HPEKLIFQSC | DYKAFYLGSM | LIKELRGTES | TQDACAKMRA | NCQKSTEQMK |
1150:
KVPTIILSVS | YKGVKFIDAT | NKNIIAEHEI | RNISCAAQDP | EDLSTFAYIT |
1200:
KDLKSNHHYC | HVFTAFDVNL | AYEIILTLGQ | AFEVAYQLAL | QARKGGHSST |
1248:
LPESFENKPS | KPIPKPRVSI | RKSVDLLHAS | HTGQEPSERH | TEEALRKF
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
ELISA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
ELISA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Human Ankyrin repeat and sterile alpha motif domain-containing protein 1B
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Fetal brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 9 AND 10)
tissue :
Amygdala .
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3; 5; 7 AND 8)
tissue :
Brain .
tissue :
Hippocampus .
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 294-1248 (ISOFORM 1);INDUCTION;TISSUE SPECIFICITY
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 425-1192 (ISOFORM 1);FUNCTION;INTERACTION WITH APP;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
10.
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Cited for : INTERACTION WITH EPHA8
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : STRUCTURE BY NMR OF 813-947;SUBCELLULAR LOCATION;NUCLEAR LOCALIZATION SIGNAL