Protein name:
Ankyrin repeat and sterile alpha motif domain-containing protein 1B ;
Alternative:
E2A-PBX1-associated protein (EB-1) ;Amyloid-beta protein intracellular domain-associated protein 1 (AIDA-1) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts with EPHA8 (By similarity). Isoform 2 interacts with COIL. Isoform 3 interacts with DLG4.
Function:
Isoform 3 can regulate global protein synthesis by altering nucleolar numbers.
Subcellular Location:
Isoform 3
Cell junction
synapse
postsynaptic cell membrane
postsynaptic density
Cell projection
dendritic spine
Nucleus
Nucleus
Cajal body
The synaptic localization requires DLG4 interaction. Translocation to the nucleus in response to stimulation of NMDA receptors (NMDARs) in a calcium-independent manner.
Protein Attributes:
50:
MGKDQELLEA | ARTGNVALVE | KLLSGRKGGI | LGGGSGPLPL | SNLLSIWRGP |
100:
NVNCTDSSGY | TALHHAALNG | HKDIVLKLLQ | FEASTNVADN | KGYFPIHLAA |
150:
WKGDVEIVKI | LIHHGPSHSR | VNEQNNENET | ALHCAAQYGH | SEVVAVLLEE |
200:
LTDPTIRNSK | LETPLDLAAL | YGRLRVVKMI | ISAHPNLMSC | NTRKHTPLHL |
250:
AARNGHKAVV | QVLLEAGMDV | SCQTEKGSAL | HEAALFGKVD | VVRVLLETGI |
300:
DANIKDSLGR | TVLDILKEHP | SQKSLQIATL | LQDYLEGVGR | SVVLEEEHAQ |
350:
EDTAQETRLS | SPAQSPSQKT | KSETVTGELS | KLLDEIKLCQ | EKDYSFEDLC |
400:
HTISDHYLDN | LSKISEEELG | KNGSQSVRTS | STINLSPGEV | EDEEEDPNSC |
450:
GPTGLWEALT | PCNGCRNLGF | PMLAQESYPK | KRNYPMEIVP | SASLDTFPSE |
500:
NENFLCELVD | TAVTKKPCSL | EIARAPSPRT | DNASEVAITA | PGTGHHRNSS |
550:
TGPTPDCSPP | SPDTALKNIV | KVIRPQPKQR | TSIVSSLDFQ | RMNHNQEYFE |
600:
ISTSTGCTSF | TSSPPVSPPT | SSVETTEIKN | EGAEHTDDLS | QQEDDEPPKE |
650:
YDAGQFAGLL | HGSSPACEAP | ENPFHLYGKR | NQGEDGQEEA | SLANSPLPFK |
700:
QTPIENNPEP | SVKKIKPKVV | SRTIFHKRSH | QLENHTIVGT | RMSRGGSRNG |
750:
DQWGVNPGGF | VERACTLGRI | RSLPKALIDM | HLSKNVSKSD | SDLIAYPSKD |
800:
KARVNWSKSS | TAERSSKDNS | ERTPSFTSEW | EEIDKIMNSI | DVGINSELEG |
850:
MNGEATRPRC | PVQTVGQWLE | SIGLPQYENH | LTANGFDNVQ | FMGSNVMEDQ |
900:
DLLEIGILNS | GHRQRILQAI | QLLPKMRPIG | HDGYHPTSVA | EWLDSIELGD |
950:
YTKAFLINGY | TSMDLLKKIW | ELELINVLKI | SLIGHRKRIL | ASLGDRLHED |
1000:
PPQKPPRSIT | LREPSGNHTP | PQLSPSLSQS | TYTTGGSLDV | PHIIMQGDAR |
1050:
RRRNENYFDD | IPRSKLERQM | AQTGDWGEPS | ITLRPPNEAT | ASTPVQYWQH |
1100:
HPEKLIFQSC | DYKAFYLGSM | LIKELRGTES | TQDACAKMRA | NCQKSTEQMK |
1150:
KVPTIILSVS | YKGVKFIDAA | NKNIIAEHEI | RNISCAAQDP | EDLSTFAYIT |
1200:
KDLKSNHHYC | HVFTAFDVNL | AYEIILTLGQ | AFEVAYQLAL | QARKGGHSST |
1250:
LPESFENKPS | KPIPKPRVSI | RKSVQIDPSE | QKTLANLPWI | VEPGQEAKRG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rat
Human
ELISA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
ELISA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
ELISA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
CLIA Kit for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Polyclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Monoclonal Antibody for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
Protein for Rat Ankyrin repeat and sterile alpha motif domain-containing protein 1B
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2 AND 3);FUNCTION;INTERACTION WITH DLG4;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;MUTAGENESIS OF 935-HIS--ARG-938;PROTEOLYTIC CLEAVAGE
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[
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[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
Brown Norway .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY (ISOFORM 3);SUBCELLULAR LOCATION