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Index > Protein center > AOX1(Gene name) > Bovine
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  • AOX1 (Gene name),
  • Aldehyde oxidase 1 (Protein name ),  AOXA_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AOX1(AO);
    Protein name:
    Aldehyde oxidase 1;
    Alternative:
    1.17.3.-;Azaheterocycle hydroxylase 1);
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Homodimer.
    Function:
    Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    1339
    Sequence:
    50:
    MEGGSELLFY | VNGRKVTEKN | VDPETMLLPY | LRKKLRLTGT | KYGCGGGGCG | 
    100:
    ACTVMISRYN | PITKKIRHYP | ANACLTPICS | LYGAAVTTVE | GIGSTKTRIH | 
    150:
    PVQERIAKCH | GTQCGFCTPG | MVMSLYTLLR | NHPEPTLTQL | NDALGGNLCR | 
    200:
    CTGYRPIINA | CKTFCKTSGC | CQSKENGVCC | LDQGMNGLPE | FEEGNETSLK | 
    250:
    LFSEEEFLPL | DPTQELIFPP | ELMTMAEKKT | QKTRIFGSDR | MTWISPVTLK | 
    300:
    ELLEAKVKYP | QAPVVMGNTS | VGPDMKFKGI | FHPVIISPDR | IEELSVVNYT | 
    350:
    DNGLTLGAAV | SLAEVKDILA | NVTRKLPEEK | TQMYHALLKH | LETLAGPQIR | 
    400:
    NMASLGGHIV | SRHPDSDLNP | LLAVGNCTLN | LLSKEGRRQI | PLNEQFLRKC | 
    450:
    PSADLKPEEI | LISVNIPYSR | KWEFVSAFRQ | AQRQQNALAI | VNSGMRVCFG | 
    500:
    KGDGIIRELS | IAYGGVGPTT | ILANNSCQKL | IGRPWNEEML | DAACRLILDE | 
    550:
    VSLPGSAPGG | RVEFKRTLIV | SFLFKFYLEV | SQILKGMDLV | HYPSLASKYE | 
    600:
    SALEDLHSRH | YWSTLKYQNA | DLKQLSQDPI | GHPIMHLSGI | KHATGEAIYC | 
    650:
    DDMPVVDREL | FLTFVTSSRA | HAKIVSIDVS | AALSLPGVVD | ILTGEHLPGI | 
    700:
    NTTFGFLTDA | DQLLSTDEVS | CVGQLVCAVI | ADSEVQARRA | AQQVKIVYQD | 
    750:
    LEPVILTIEE | AIQNKSFFEP | ERKLEYGNVD | EAFKMVDQIL | EGEIHMGGQE | 
    800:
    HFYMETQSML | VVPKGEDREI | DVYVSAQFPK | YIQDITASVL | KVSANKVMCH | 
    850:
    VKRVGGAFGG | KVTKTGVLAA | ITAFAANKHG | RPVRCILERG | EDILITGGRH | 
    900:
    PYLGKYKAGF | MNDGRILALD | MEHYNNAGAF | LDESLFVIEM | GLLKLENAYK | 
    950:
    FPNLRCRGWA | CRTNLPSNTA | LRGFGFPQAG | LITEACITEV | AAKCGLPPEK | 
    1000:
    VRMINMYKEI | DQTPYKQEIN | TKNLTQCWKE | CMATSSYTLR | KAAVEKFNSE | 
    1050:
    NYWKKKGLAM | VPLKYPIGLG | SVAAGQAAAL | VHIYLDGSVL | VTHGGIEMGQ | 
    1100:
    GVHTKMIQVV | SRELRMPLSS | IHLRGTSTET | IPNTNPSGGS | VVADLNGLAV | 
    1150:
    KDACQTLLKR | LKPIISKNPK | GTWKDWAQAA | FNESISLSAT | GYFRGYESNI | 
    1200:
    NWETGEGHPF | EYFVYGAACS | EVEIDCLTGA | HKNIRTDIVM | DVGYSINPAL | 
    1250:
    DVGQIEGAFI | QGMGLYTIEE | LNYSPQGVLY | TRGPNQYKIP | AICDIPMELH | 
    1300:
    ISFLPPSENS | NTLYSSKGLG | ESGIFLGCSV | FFAIHDAIRA | ARQERGLPGP | 
    1339:
    LRLNSPLTPE | KIRMACEDKF | TKMIPRDEPG | SYVPWSVPI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Aldehyde oxidase 1
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    ELISA Kit for Bovine Aldehyde oxidase 1
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    ELISA Kit for Bovine Aldehyde oxidase 1
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    ELISA Kit for Bovine Aldehyde oxidase 1
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    Packing:
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    CLIA Kit for Bovine Aldehyde oxidase 1
    Cat.:
    U5988r
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    Please sign in first.
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    Packing:
    96T
    CLIA Kit for Bovine Aldehyde oxidase 1
    Cat.:
    U5988m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Aldehyde oxidase 1
    Cat.:
    U5988b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Aldehyde oxidase 1
    MSDS:
    Please sign in first.
    CLIA Kit for Bovine Aldehyde oxidase 1
    Cat.:
    U5988h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Aldehyde oxidase 1
    Polyclonal Antibody for Bovine Aldehyde oxidase 1
    Polyclonal Antibody for Bovine Aldehyde oxidase 1
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Aldehyde oxidase 1
    Cat.:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Aldehyde oxidase 1
    Monoclonal Antibody for Bovine Aldehyde oxidase 1
    Monoclonal Antibody for Bovine Aldehyde oxidase 1
    Monoclonal Antibody for Bovine Aldehyde oxidase 1
    Monoclonal Antibody for Bovine Aldehyde oxidase 1
    Monoclonal Antibody for Bovine Aldehyde oxidase 1
    Protein for Bovine Aldehyde oxidase 1
    Protein for Bovine Aldehyde oxidase 1
    Protein for Bovine Aldehyde oxidase 1
    Protein for Bovine Aldehyde oxidase 1
    Protein for Bovine Aldehyde oxidase 1

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    References
    1. 1.
      "Purification, cDNA cloning, and tissue distribution of bovine liver aldehyde oxidase."
      Calzi M.L. , Raviolo C. , Ghibaudi E. , de Gioia L. , Salmona M. , Cazzaniga G. , Kurosaki M. , Terao M. , Garattini E.
      J. Biol. Chem.270:31037-31045(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 43-48; 187-218 AND 538-573;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;HOMODIMER;BLOCKAGE OF N-TERMINUS
      tissue: Liver.
    2. 2.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Hereford.
      tissue: Uterus.
    3. 3.
      "Structure and evolution of vertebrate aldehyde oxidases: from gene duplication to gene suppression."
      Kurosaki M. , Bolis M. , Fratelli M. , Barzago M.M. , Pattini L. , Perretta G. , Terao M. , Garattini E.
      Cell. Mol. Life Sci.70:1807-1830(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PARALOGS
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