Protein name:
Aldehyde oxidase 1 ;
Alternative:
1.17.3.-;Azaheterocycle hydroxylase 1 ) ;
Organism:
Bovine (Bos taurus).
General Annotation
Function:
Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis.
Subcellular Location:
Cytoplasm
Protein Attributes:
50:
MEGGSELLFY | VNGRKVTEKN | VDPETMLLPY | LRKKLRLTGT | KYGCGGGGCG |
100:
ACTVMISRYN | PITKKIRHYP | ANACLTPICS | LYGAAVTTVE | GIGSTKTRIH |
150:
PVQERIAKCH | GTQCGFCTPG | MVMSLYTLLR | NHPEPTLTQL | NDALGGNLCR |
200:
CTGYRPIINA | CKTFCKTSGC | CQSKENGVCC | LDQGMNGLPE | FEEGNETSLK |
250:
LFSEEEFLPL | DPTQELIFPP | ELMTMAEKKT | QKTRIFGSDR | MTWISPVTLK |
300:
ELLEAKVKYP | QAPVVMGNTS | VGPDMKFKGI | FHPVIISPDR | IEELSVVNYT |
350:
DNGLTLGAAV | SLAEVKDILA | NVTRKLPEEK | TQMYHALLKH | LETLAGPQIR |
400:
NMASLGGHIV | SRHPDSDLNP | LLAVGNCTLN | LLSKEGRRQI | PLNEQFLRKC |
450:
PSADLKPEEI | LISVNIPYSR | KWEFVSAFRQ | AQRQQNALAI | VNSGMRVCFG |
500:
KGDGIIRELS | IAYGGVGPTT | ILANNSCQKL | IGRPWNEEML | DAACRLILDE |
550:
VSLPGSAPGG | RVEFKRTLIV | SFLFKFYLEV | SQILKGMDLV | HYPSLASKYE |
600:
SALEDLHSRH | YWSTLKYQNA | DLKQLSQDPI | GHPIMHLSGI | KHATGEAIYC |
650:
DDMPVVDREL | FLTFVTSSRA | HAKIVSIDVS | AALSLPGVVD | ILTGEHLPGI |
700:
NTTFGFLTDA | DQLLSTDEVS | CVGQLVCAVI | ADSEVQARRA | AQQVKIVYQD |
750:
LEPVILTIEE | AIQNKSFFEP | ERKLEYGNVD | EAFKMVDQIL | EGEIHMGGQE |
800:
HFYMETQSML | VVPKGEDREI | DVYVSAQFPK | YIQDITASVL | KVSANKVMCH |
850:
VKRVGGAFGG | KVTKTGVLAA | ITAFAANKHG | RPVRCILERG | EDILITGGRH |
900:
PYLGKYKAGF | MNDGRILALD | MEHYNNAGAF | LDESLFVIEM | GLLKLENAYK |
950:
FPNLRCRGWA | CRTNLPSNTA | LRGFGFPQAG | LITEACITEV | AAKCGLPPEK |
1000:
VRMINMYKEI | DQTPYKQEIN | TKNLTQCWKE | CMATSSYTLR | KAAVEKFNSE |
1050:
NYWKKKGLAM | VPLKYPIGLG | SVAAGQAAAL | VHIYLDGSVL | VTHGGIEMGQ |
1100:
GVHTKMIQVV | SRELRMPLSS | IHLRGTSTET | IPNTNPSGGS | VVADLNGLAV |
1150:
KDACQTLLKR | LKPIISKNPK | GTWKDWAQAA | FNESISLSAT | GYFRGYESNI |
1200:
NWETGEGHPF | EYFVYGAACS | EVEIDCLTGA | HKNIRTDIVM | DVGYSINPAL |
1250:
DVGQIEGAFI | QGMGLYTIEE | LNYSPQGVLY | TRGPNQYKIP | AICDIPMELH |
1300:
ISFLPPSENS | NTLYSSKGLG | ESGIFLGCSV | FFAIHDAIRA | ARQERGLPGP |
1339:
LRLNSPLTPE | KIRMACEDKF | TKMIPRDEPG | SYVPWSVPI
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Rabbit
Rat
Bovine
Human
ELISA Kit for Bovine Aldehyde oxidase 1
ELISA Kit for Bovine Aldehyde oxidase 1
ELISA Kit for Bovine Aldehyde oxidase 1
ELISA Kit for Bovine Aldehyde oxidase 1
ELISA Kit for Bovine Aldehyde oxidase 1
CLIA Kit for Bovine Aldehyde oxidase 1
CLIA Kit for Bovine Aldehyde oxidase 1
CLIA Kit for Bovine Aldehyde oxidase 1
CLIA Kit for Bovine Aldehyde oxidase 1
CLIA Kit for Bovine Aldehyde oxidase 1
Polyclonal Antibody for Bovine Aldehyde oxidase 1
Polyclonal Antibody for Bovine Aldehyde oxidase 1
Polyclonal Antibody for Bovine Aldehyde oxidase 1
Polyclonal Antibody for Bovine Aldehyde oxidase 1
Polyclonal Antibody for Bovine Aldehyde oxidase 1
Monoclonal Antibody for Bovine Aldehyde oxidase 1
Monoclonal Antibody for Bovine Aldehyde oxidase 1
Monoclonal Antibody for Bovine Aldehyde oxidase 1
Monoclonal Antibody for Bovine Aldehyde oxidase 1
Monoclonal Antibody for Bovine Aldehyde oxidase 1
Protein for Bovine Aldehyde oxidase 1
Protein for Bovine Aldehyde oxidase 1
Protein for Bovine Aldehyde oxidase 1
Protein for Bovine Aldehyde oxidase 1
Protein for Bovine Aldehyde oxidase 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Purification, cDNA cloning, and tissue distribution of bovine liver aldehyde oxidase."
Calzi M.L.
,
Raviolo C.
,
Ghibaudi E.
,
de Gioia L.
,
Salmona M.
,
Cazzaniga G.
,
Kurosaki M.
,
Terao M.
,
Garattini E.
J. Biol. Chem.270:31037-31045(1995)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 43-48; 187-218 AND 538-573;FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;HOMODIMER;BLOCKAGE OF N-TERMINUS
tissue :
Liver .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Uterus .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION OF PARALOGS