AOX1 ELISA Kit for Rabbit(Oryctolagus cuniculus) | EIAab.comAOX1 ELISA Kit for Rabbit(Oryctolagus cuniculus)

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Index > Protein center > AOX1(Gene name) > Rabbit

AOX1 (Gene name),

Aldehyde oxidase 1 (Protein name ), AOXA_RABIT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

AOX1(AO);

Protein name:

Aldehyde oxidase 1;

Alternative:

Retinal oxidase;1.17.3.-;Azaheterocycle hydroxylase 1);Retinoic acid synthase;

Organism:

Rabbit (Oryctolagus cuniculus).

General Annotation

Sub Unit:

Homodimer.

Function:

Oxidase with broad substrate specificity, oxidizing aromatic azaheterocycles, such as N1-methylnicotinamide and N-methylphthalazinium, as well as aldehydes, such as benzaldehyde, retinal, pyridoxal, and vanillin. Plays a key role in the metabolism of xenobiotics and drugs containing aromatic azaheterocyclic substituents. Participates in the bioactivation of prodrugs such as famciclovir, catalyzing the oxidation step from 6-deoxypenciclovir to penciclovir, which is a potent antiviral agent. Is probably involved in the regulation of reactive oxygen species homeostasis. May be a prominent source of superoxide generation via the one-electron reduction of molecular oxygen. Also may catalyze nitric oxide (NO) production via the reduction of nitrite to NO with NADH or aldehyde as electron donor. May play a role in adipogenesis. Cannot use hypoxanthine and all-trans-retinol as substrate.

Subcellular Location:

Cytoplasm

Protein Attributes:

Sequence length:

1334

Sequence:

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1334:

PLTPEKIRMA | CEDKFTKMIP | RDKPGSYVPW | NVPV

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF01315

SMR:

P80456

STRING:

9986.ENSOCUP00000012025

UniGene:

Ocu.2359

Uniprot:

P80456

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ELISA Kit for Rabbit Aldehyde oxidase 1

Cat.:

E5988m

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96T

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ELISA Kit for Rabbit Aldehyde oxidase 1

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ELISA Kit for Rabbit Aldehyde oxidase 1

Cat.:

E5988r

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96T

ELISA Kit for Rabbit Aldehyde oxidase 1

Cat.:

E5988b

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96T

ELISA Kit for Rabbit Aldehyde oxidase 1

Cat.:

E5988h

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Packing:

96T

CLIA Kit for Rabbit Aldehyde oxidase 1

Cat.:

U5988r

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Packing:

96T

CLIA Kit for Rabbit Aldehyde oxidase 1

Cat.:

U5988m

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MSDS:

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Packing:

96T

CLIA Kit for Rabbit Aldehyde oxidase 1

Cat.:

U5988b

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MSDS:

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Packing:

96T

CLIA Kit for Rabbit Aldehyde oxidase 1

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CLIA Kit for Rabbit Aldehyde oxidase 1

Cat.:

U5988h

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96T

Polyclonal Antibody for Rabbit Aldehyde oxidase 1

Cat.:

P5988Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Aldehyde oxidase 1

Cat.:

P5988Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Rabbit Aldehyde oxidase 1

Monoclonal Antibody for Rabbit Aldehyde oxidase 1

Protein for Rabbit Aldehyde oxidase 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning of retinal oxidase/aldehyde oxidase cDNAs from rabbit and mouse livers and functional expression of recombinant mouse retinal oxidase cDNA in Escherichia coli."
Huang D.-Y. , Furukawa A. , Ichikawa Y.
Arch. Biochem. Biophys.364:264-272(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 857-884; 891-943 AND 1272-1293;FUNCTION;TISSUE SPECIFICITY
strain: Japanese white.
tissue: Liver.
2.

"Properties of rabbit liver aldehyde oxidase and the relationship of the enzyme to xanthine oxidase and dehydrogenase."
Turner N.A. , Doyle W.A. , Ventom A.M. , Bray R.C.
Eur. J. Biochem.232:646-657(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 203-231 AND 574-597;FUNCTION AS OXIDASE;COFACTOR
tissue: Liver.
3.

"Characteristic properties of retinal oxidase (retinoic acid synthase) from rabbit hepatocytes."
Tsujita M. , Tomita S. , Miura S. , Ichikawa Y.
Biochim. Biophys. Acta1204:108-116(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS OXIDASE;CATALYTIC ACTIVITY;SUBSTRATE SPECIFICITY;BIOPHYSICOCHEMICAL PROPERTIES;HOMODIMER;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;REACTION MECHANISM;BLOCKAGE OF N-TERMINUS;ENZYME REGULATION
4.

"In vitro oxidation of famciclovir and 6-deoxypenciclovir by aldehyde oxidase from human, guinea pig, rabbit, and rat liver."
Rashidi M.R. , Smith J.A. , Clarke S.E. , Beedham C.
Drug Metab. Dispos.25:805-813(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION AS AZAHETEROCYCLE OXIDASE;CATALYTIC ACTIVITY;ENZYME REGULATION;BIOPHYSICOCHEMICAL PROPERTIES
5.

"Structure and evolution of vertebrate aldehyde oxidases: from gene duplication to gene suppression."
Kurosaki M. , Bolis M. , Fratelli M. , Barzago M.M. , Pattini L. , Perretta G. , Terao M. , Garattini E.
Cell. Mol. Life Sci.70:1807-1830(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION OF PARALOGS

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