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Index > Protein center > AP1B1(Gene name) > Human
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  • AP1B1 (Gene name),
  • AP-1 complex subunit beta-1 (Protein name ),  AP1B1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    AP1B1(ADTB1;BAM22;CLAPB2);
    Protein name:
    AP-1 complex subunit beta-1;
    Alternative:
    Adaptor protein complex AP-1 subunit beta-1;Adapter-related protein complex 1 subunit beta-1;Beta-adaptin 1;Beta-1-adaptin;Golgi adaptor HA1/AP1 adaptin beta subunit;Clathrin assembly protein complex 1 beta large chain;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Adaptor protein complex 1 (AP-1) is an heterotetramer composed of two large adaptins (gamma-type subunit AP1G1 and beta-type subunit AP1B1), a medium adaptin (mu-type subunit AP1M1 or AP1M2) and a small adaptin (sigma-type subunit AP1S1 or AP1S2 or AP1S3).
    Function:
    Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
    Subcellular Location:
    Golgi apparatus Cytoplasmic vesicle clathrin-coated vesicle membrane Peripheral membrane protein Cytoplasmic side Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
    Protein Attributes:
    Sequence length:
    949
    Sequence:
    50:
    MTDSKYFTTT | KKGEIFELKA | ELNSDKKEKK | KEAVKKVIAS | MTVGKDVSAL | 
    100:
    FPDVVNCMQT | DNLELKKLVY | LYLMNYAKSQ | PDMAIMAVNT | FVKDCEDPNP | 
    150:
    LIRALAVRTM | GCIRVDKITE | YLCEPLRKCL | KDEDPYVRKT | AAVCVAKLHD | 
    200:
    INAQLVEDQG | FLDTLKDLIS | DSNPMVVANA | VAALSEIAES | HPSSNLLDLN | 
    250:
    PQSINKLLTA | LNECTEWGQI | FILDCLANYM | PKDDREAQSI | CERVTPRLSH | 
    300:
    ANSAVVLSAV | KVLMKFMEML | SKDLDYYGTL | LKKLAPPLVT | LLSAEPELQY | 
    350:
    VALRNINLIV | QKRPEILKHE | MKVFFVKYND | PIYVKLEKLD | IMIRLASQAN | 
    400:
    IAQVLAELKE | YATEVDVDFV | RKAVRAIGRC | AIKVEQSAER | CVSTLLDLIQ | 
    450:
    TKVNYVVQEA | IVVIKDIFRK | YPNKYESVIA | TLCENLDSLD | EPEARAAMIW | 
    500:
    IVGEYAERID | NADELLESFL | EGFHDESTQV | QLQLLTAIVK | LFLKKPTETQ | 
    550:
    ELVQQVLSLA | TQDSDNPDLR | DRGYIYWRLL | STDPVAAKEV | VLAEKPLISE | 
    600:
    ETDLIEPTLL | DELICYIGTL | ASVYHKPPSA | FVEGGRGVVH | KSLPPRTASS | 
    650:
    ESAESPETAP | TGAPPGEQPD | VIPAQGDLLG | DLLNLDLGPP | VSGPPLATSS | 
    700:
    VQMGAVDLLG | GGLDSLMGDE | PEGIGGTNFV | APPTAAVPAN | LGAPIGSGLS | 
    750:
    DLFDLTSGVG | TLSGSYVAPK | AVWLPAMKAK | GLEISGTFTR | QVGSISMDLQ | 
    800:
    LTNKALQVMT | DFAIQFNRNS | FGLAPATPLQ | VHAPLSPNQT | VEISLPLSTV | 
    850:
    GSVMKMEPLN | NLQVAVKNNI | DVFYFSTLYP | LHILFVEDGK | MDRQMFLATW | 
    900:
    KDIPNENEAQ | FQIRDCPLNA | EAASSKLQSS | NIFTVAKRNV | EGQDMLYQSL | 
    949:
    KLTNGIWVLA | ELRIQPGNPS | CTDLELSLKC | RAPEVSQHVY | QAYETILKN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    String:
    KEGG:
    MIM:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human AP-1 complex subunit beta-1
    ELISA Kit for Human AP-1 complex subunit beta-1
    ELISA Kit for Human AP-1 complex subunit beta-1
    ELISA Kit for Human AP-1 complex subunit beta-1
    CLIA Kit for Human AP-1 complex subunit beta-1
    CLIA Kit for Human AP-1 complex subunit beta-1
    CLIA Kit for Human AP-1 complex subunit beta-1
    CLIA Kit for Human AP-1 complex subunit beta-1
    Polyclonal Antibody for Human AP-1 complex subunit beta-1
    Polyclonal Antibody for Human AP-1 complex subunit beta-1
    Polyclonal Antibody for Human AP-1 complex subunit beta-1
    Polyclonal Antibody for Human AP-1 complex subunit beta-1
    Monoclonal Antibody for Human AP-1 complex subunit beta-1
    Monoclonal Antibody for Human AP-1 complex subunit beta-1
    Monoclonal Antibody for Human AP-1 complex subunit beta-1
    Monoclonal Antibody for Human AP-1 complex subunit beta-1
    Protein for Human AP-1 complex subunit beta-1
    Protein for Human AP-1 complex subunit beta-1
    Protein for Human AP-1 complex subunit beta-1
    Protein for Human AP-1 complex subunit beta-1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Characterization of a new member of the human beta-adaptin gene family from chromosome 22q12, a candidate meningioma gene."
      Peyrard M. , Fransson I. , Xie Y.-G. , Han F.-Y. , Ruttledge M.H. , Swahn S. , Collins J.E. , Dunham I. , Collins V.P. , Dumanski J.P.
      Hum. Mol. Genet.3:1393-1399(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B);VARIANT ALA-777
      tissue: Brain.
    2. 2.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM C);VARIANT ALA-777
    3. 3.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4);VARIANT ALA-777
      tissue: Lymph.
    5. 5.
      "Structure of the promoter and genomic organization of the human beta'-adaptin gene (BAM22) from chromosome 22q12."
      Peyrard M. , Pan H.-Q. , Kedra D. , Fransson I. , Swahn S. , Hartman K. , Clifton S.W. , Roe B.A. , Dumanski J.P.
      Genomics36:112-117(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-922;VARIANT ALA-777
    6. 6.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-318;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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